Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 554 (1979), S. 1-22 
    ISSN: 0005-2736
    Keywords: (Electron microscopy) ; Membrane protein ; Membrane structure ; Phase separation ; Picture analysis
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 84 (1978), S. 508-514 
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Macmillan Magazines Ltd.
    Nature 400 (1999), S. 544-547 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The observation that clusters of neutral H2O () or SO2 (ref. 5) molecules, on impact with essentially any solid surface, can decay efficiently into positively and negatively charged fragments has defied explanation, not least because the kinetic energy ...
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    ISSN: 0196-9781
    Keywords: ''Incretin'' deficiency ; Conscious Beagle dog ; Entero-insular axis of insulin ; Oral and intravenous glucose administration ; Pancreas atrophy ; Pancreatic duct occlusion ; Somatostatin ; VIP ; VIP is no ''incretin''
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    ISSN: 0014-5793
    Keywords: Anoxia ; Heart cell ; K"A"T"P channel ; Patch clamp
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 5 (1981), S. 721-724 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Le cancer gastrique précoce est défini par un carcinome dont la localisation est limitée à la muqueuse et la sous muqueuse. En fonction de cette définition on peut considérer 2 types de carcinome le cancer muqueux et le cancer sous muqueux. L'existence ou non de métastases ganglionnaires n'est pas à prendre en considération dans la définition. Les progrès les plus marqués dans la détection du cancer de l'estomac ont été faits au Japon depuis 1960. Dès maintenant, près de 30% de tous les malades qui présentènt un cancer de l'estomac sont traités à un stade précoce dans ce pays. Cependant, en Europe, des progrès ont été également atteints. Avant la pratique de l'endoscopie le taux des cancers traités à un stade précoce était inférieur à 3%. Depuis lors il s'est élevé à 6% dans la plupart des pays européens et a même atteint 16% dans notre formation hospitalière. Le diagnostic de cancer précoce est établi le plus souvent par endoscopie. Le taux de fiabilité de la gastroscopie est d'environ 92% (Rösch) et atteint même 98% lorsque l'endoscopie est compétée par la biopsie. En raison du fait que le cancer de l'estomac est multifocal dans plus de 10%, l'endoscopiste doit systématiquement rechercher une seconde ou une troisième localisation au niveau de la totalité de l'estomac. Pour établir fermement le diagnostic de cancer en présence d'une ulcération, de multiples prélèvements doivent être effectués aussi bien au niveau du fond que des bords de l'ulcération. Les lésions ulcéreuses malignes pouvant régresser de temps en temps et même cicatrisées les prélèvements doivent être faits en présence de lésions cicatricielles. Lorsque les lésions revêtent un type polypöide, une large excision est nécessaire pour établir le diagnostic. Dans quelques cas choisie, elle représente une méthode thérapeutique.
    Notes: Abstract In the last 10 years, 130 patients with early gastric carcinoma were operated on at the Surgical University Clinic of Erlangen. The ulcerous type was the most frequent (85%) and had the best prognosis with a 5-year survival rate of 87% excluding operative mortality, and 100% when agecorrected.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 259 (1998), S. 233-245 
    ISSN: 1617-4623
    Keywords: Key words Simple sequence repeat ; Linkage map ; Single-strand hybridisation ; Triplex affinity capture ; Enriched library
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Solanum tuberosum L. DNA sequences containing simple sequence repeat (SSR) motifs were extracted from the EMBL database, cDNA and selectively enriched small-insert DNA libraries. Enrichment was achieved using either triplex affinity capture or single-strand hybridisation selection. One hundred and twelve primer pairs which successfully amplified products of the correct size from potato DNA were ultimately designed and synthesised. Ninety-eight of these revealed length polymorphisms in a panel of four diploid and two tetraploid clones, in agreement with the high information content of this class of markers which has been found in other species. All of the markers were assigned a quality score of 1–5 based on their potential usefulness. Eighty-nine loci from 65 of the primer pairs were located on two genetic linkage maps of potato by segregation analysis of the amplified alleles. Fifty-two of the SSRs were clearly single locus. The maps were aligned using 23 SSR primer pairs and 13 RFLP loci mapped in both populations. The markers described constitute a class which should replace Restriction Fragment Length Polymorphisms (RFLP) as the markers of choice for future genetic studies in potato. The sequences of the primers, together with other information on these markers are provided.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    ISSN: 1617-4623
    Keywords: Key wordsBeta vulgaris ; Functional genes ; Genetic mapping ; Heteroduplex analysis ; Single-strand conformation polymorphism (SSCP)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract To analyse genetic factors that potentially affect sugar quality and yield in Beta vulgaris, we designed primers based on 18 homologous ESTs and conserved regions of 32 heterologous ESTs encoding gene products that act in the Calvin cycle, the oxidative pentose phosphate cycle, photorespiration, synthesis, transport and degradation of sucrose, glycolysis, the citric acid cycle, nitrogen metabolism and osmoprotection. Data on the amplification of 54 gene homologues from B. vulgaris are presented. Among these are 35 homologues for which DNA sequence information from B. vulgaris is now available for the first time. For genetic mapping a PCR-based strategy using CAPS (cleaved amplified polymorphic sequence), DFLP (DNA fragment length polymorphism), SSCP (single-strand conformation polymorphism) and HD (heteroduplex) analysis was adopted. RFLP analysis was also used in some cases. The different techniques used for the detection of polymorphisms are evaluated with respect to their sensitivity and versatility. In all, 42 functional genes have been assigned to the nine linkage groups of sugar beet.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 5 (1981), S. 269-273 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé L'article analyse 117 duodénopancréatectomies pour pancréatite chronique, 49 partielles et 68 totales. La mortalité opératoire a été 8.2% pour les résections partielles et de 20.6% pour les totales. Les opérés ont été suivis pendant 6 1/2 années: 76% des résections partielles et 63% des totales ont continué à boire autant d'alcool qu'avant l'intervention. Avant pancréatectomie totale, 42% des malades étaient diabétiques; après cette opération, tous avaient un diabète, difficile à équilibrer à l'insuline dans 75% des cas qui ont souffert d'épisodes répétés de choc hypoglycémique. La mortalité tardive a été de 20.4% après duodénopancréatectomie partielle et de 19.1% après résection totale. Après pancréatectomie totale, 50% des décès tardifs ont été dus aux accidents d'hypoglycémie. A la fin de la période de follow-up, la survie du groupe pancréatectomie totale est de 11% inférieure à celle des résections partielles. La pancréactectomie totale n'est justifiée que chez les malades qui ont, avant l'intervention, un diabète exigeant l'administration d'insuline. Nous décrivons une nouvelle technique qui réalise, après résection de la tête du pancréas, une occlusion des canaux pancréatiques par injection d'une solution d'acides aminés à prise rapide, ce qui entraîne après quelques semaines une atrophie du pancréas exocrine. Cette technique a été utilisée chez 39 malades, avec 2.5% de décès et 7.6% de complications postopératoires. Nous estimons que cette nouvelle technique peut réduire nettement le risque opératoire de la duodénopancréatectomie partielle pour pancréatite chronique et améliorer les résultats à long terme.
    Notes: Abstract This is a report of 117 pancreaticoduodenectomies performed for chronic pancreatitis, of which 49 were partial and 68 were total. The operative mortality rate of partial pancreaticoduodenectomy was 8.2% and of total pancreatectomy was 20.6%. During a follow-up period of 6 1/2 years, 76% and 63% of the surgical patients, respectively, continued to drink alcohol as heavily as before. Prior to total pancreatectomy, only 42% of the patients had diabetes. After total extirpation of the organ, all had diabetes and 75% were very difficult to stabilize with insulin, experiencing repeated episodes of hypoglycemic shock. The additional late mortality rate was 20.4% following partial pancreaticoduodenectomy and 19.1% after total resection. After total pancreatectomy, 50% of the late deaths were due to hypoglycemia. After total pancreatectomy, 11% fewer patients were still alive at the end of the follow-up period than after partial pancreaticoduodenectomy. Total pancreatectomy is justified only in patients who already have diabetes requiring insulin. A new technique is described in which, following resection of the head of the pancreas, the duct system is occluded by injection of a rapidly hardening amino acid solution, leading to atrophy of the excretory pancreas within a few weeks. This procedure has been carried out in 39 patients with a mortality rate of 2.5% and postoperative complications in 7.6%. We believe that the immediate risk of partial pancreaticoduodenectomy in chronic pancreatitis can be decreased markedly and the late results improved by this new technique.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    ISSN: 1432-2242
    Keywords: Solanum spegazzinii ; Globodera rostochi ensis ; Nematode resistance ; QTL ; RFLP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We report the identification and mapping of two quantitative trait loci (QTLs) of Solanum spegazzinii BGRC, accession 8218-15, involved in resistance to the potato cyst-nematode Globodera rostochiensis pathotype Ro1, by means of restriction fragment length polymorphisms (RFLPs). For this purpose we crossed a susceptible diploid S. tuberosum with the resistant S. spegazzinii, and tested the F1 population for resistance to the Ro1 pathotype. Since the F1 segregated for the resistance, the S. spegazzinii parent was concluded to be heterozygous at the nematode resistance loci. For the mapping of the resistance loci we made use of RFLP markers segregating for S. spegazzinii alleles in the F1. One hundred and seven RFLP markers were tested in combination with four different restriction enzymes; 29 of these displayed a heterozygous RFLP pattern within S. spegazzinii and were used for mapping. Analysis of variance (ANOVA) was applied to test the association of the RFLP patterns of these markers with nematode resistance. Two QTLs involved in disease resistance to Globodera rostochiensis pathotype Ro1 were identified and mapped to chromosomes 10 and 11 respectively.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...