ISSN:
0009-2940
Keywords:
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Hydroxylamines in the Four-Component Condensation (Ugi Reaction), IIHydroxylamines undergo the title reaction in the presence of hydrazoic acid to give the expected 1,5-disubstituted tetrazoles. In the case of an unsubstituted NH2 group a N,N-disubstituted reaction product is obtained, whereas in the case of severe steric hindrance the corresponding (hydroxyalkyl)tetrazole is formed. A few of the tetrazoles obtained were converted to acylderivatives, some of which are susceptible to side-chain pyrolysis under relatively mild conditions.
Notes:
Auf Hydroxylamine wird die Tetrazol-Variante der Titelreaktion angewandt; bei Vorliegen freier NH2-Gruppen tritt doppelte Umsetzung ein, während stärkere sterische Hinderung lediglich zur Bildung entsprechender (Hydroxyalkyl)tetrazole führt. Einige Produkte werden als Acylderivate charakterisiert, von denen ein Teil bei relativ niedriger Temperatur einer Seitenketten-Pyrolyse unterliegt.
Additional Material:
4 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19741070918
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