Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Biodegradable Porous PCL/HA Scaffolds for Bone Tissue Engineering (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 342-343 (July 2007), p. 77-80 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Poly ε-caprolactone(PCL)/hydroxyapatite(HA) composite scaffolds were fabricated byparticulate leaching and freeze drying routes with different HA content. Porosity was decreasedwith HA addition, while mean pore size was maintained at around porogen size regardless of HAcontent. Compressive modulus was increased with increasing HA content. In this study, theoptimum content of HA was around 40% in weight against PCL to obtain the highest compressivemodulus with keeping porosity above 85%. HA apparently enhanced proliferation of osteoblast-likeMG63 cells in PCL/HA composite scaffolds. Typical adhesion, migration and aggregationprocedure of MG63 cells were found on PCL, while spreading morphology only was found on HAeven at the early stage of adhesion without migration or aggregation
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.77.pdf
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Characterization of PCL/HA Composite Scaffolds for Bone Tissue Engineering (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 342-343 (July 2007), p. 109-112 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Porous and bioactive composite scaffolds based on poly ε-caprolactone(PCL) andhydroxyapatite(HA) were successfully fabricated by solvent casting and salt leaching method. Thescaffolds have interconnected pore structure with pore size ranging from 10μm to 500μm. The poresize of PCL scaffold and PCL/HA scaffold were similar to that of the salt particles. The pore wallsbecame thick and the small pores on the surface of macropores were formed as the HA increased.MTT assay showed that HA content did not affect initial cell attachment in both PCL scaffolds andPCL/HA scaffolds. The osteoblasts proliferated in both scaffolds, but the cell number was higher inthe PCL/HA composite scaffolds. It was found that the incorporation of hydroxyapatite enhancesbone cell proliferation rather than initial cell attachment in PCL/HA composite scaffolds. Theresults suggest that the PCL/HA composite scaffolds have a potential for the bone tissueengineering applications
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.109.pdf
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    In Vitro Evaluation of Poly ε-Caprolactone/Hydroxyapatite Composite as Scaffolds for Bone Tissue Engineering with Human Bone Marrow Stromal Cells (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 342-343 (July 2007), p. 369-372 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This study evaluated the potential of the PCL (poly [removed info]-caprolactone)/HA(Hydroxyapatite)composite materials as a scaffold for bone regeneration. For this, we fabricated scaffolds utilizingsalt leaching method. The PCL/HA composite scaffolds were prepared with various HA contents(20wt%, 40wt%, 60 wt %). To ensure the potential for the scaffolds, porosity tests were conductedalong with SEM observations. The porosity decreased with the increase of the contents of HAparticles. The porosity of the composite with the highest contents of HA was still adoptable (~85%).In addition, the PCL/HA composite scaffolds were evaluated for their ability of osteogenicdifferentiation with human bone marrow stromal cell (hBMSC) in vitro. Alkaline phosphatase(ALP) activity, markers for osteoblastic differentiation, and total protein contents were evaluated inhBMSCs following 14 days of cultivation. The addition of HA particles enhanced proliferation ofhBMSC during the test. Also, the differentiation ability of the cells was increased as HA particleswere added. In this study, we concluded that PCL/HA composite scaffolds has great potential as ascaffold for bone tissue engineering
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.369.pdf
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Evaluation of Bonding Stress for the Newly Suggested Bone Cement: Comparison with Currently Used PMMA through Animal Studies (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 342-343 (July 2007), p. 373-376 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: PMMA remains the most popular material of bone cement for orthopaedic surgeries.However, conventional PMMA bone cement still has some problems. For this, we suggested newcomposite material (BBC) consisting of hydroxyapatite (45%), chitosan (10%) and PMMA. Thepurpose of this study was to evaluate the bonding stress at the interface of PMMA with additivesand host bone using a rabbit model. After 6, 12 weeks of operation, the bonding stresses wereevaluated by measuring shear stress through push-out test. The results of the tests showed that after6 weeks the shear stress of the BBC was 2.65±0.29MPa and the PMMA was 1.21±0.31MPa(p〈0.05). However, after 12 weeks, there were no significant differences between BBC andconventional PMMA bone cement. In SEM analysis, bone surface of BBC showed higherroughness than that of conventional PMMA bone cement after push-out test. From the study weconducted, addition of HA particles and chitosan to conventional PMMA bone cement showedpromising results. The BBC has clinical potential of bone substitutes replacing conventionalPMMA
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.373.pdf
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Implant Surface Conditioning with Tetracycline-HCl: A SEM Study (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 361-363 (Nov. 2007), p. 849-852 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The increased surface roughness of dental implants has shown enhanced integration ofbone tissues to implant surfaces, but may be predisposed to an increased risk of pathogenic bacterialinfection and contamination with bacterial products. Tetracycline-HCl (Tc) treatment has beenregarded as a practical and effective chemical modality for decontamination and detoxification ofcontaminated implant surfaces. The purpose of this study was to examine if Tc treatment alters themicrostructures of the modified surface of dental implants. For this purpose, dental implants withpure titanium machined surface (MS), sandblasted, large grit, acid-etched surface (SLAS), oranodized surface (AS) were used. The surface of dental implants was rubbed for 30, 60, 90, 120, or150 sec with sponge pellets soaked in Tc solution (50mg/ml) and in distilled water for 0 and 150 secas the control group. The specimens were then routinely processed for scanning electronmicroscopy. The results show that Tc treatment did not change the surface of MS, SLAS, and AS
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.361-363.849.pdf
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...