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  • 1
    Electronic Resource
    Electronic Resource
    An alternative approach to estimation of the brain perfusion index for measurement of cerebral blood flow using technetium-99m compounds (1999)
    Springer
    European journal of nuclear medicine 26 (1999), S. 1333-1339 
    Details
    ISSN: 1619-7089
    Keywords: Key words: Brain perfusion index ; Spectral analysis ; Graphical analysis ; Technetium-99m hexamethylpropylene amine oxime ; Technetium-99m ethyl cysteinate dimer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Cerebral blood flow (CBF) has been quantified non-invasively using the brain perfusion index (BPI) determined from radionuclide angiographic data generated by technetium-99m hexamethylpropylene amine oxime(99mTc-HMPAO) or technetium-99m ethyl cysteinate dimer(99mTc-ECD). The BPI is generally calculated using graphical analysis (GA). In the present study, BPI was measured using spectral analysis (SA), and its usefulness evaluated in comparison with GA. The BPI was calculated from the sum of spectral data obtained by SA. We applied this method to radionuclide angiographic data collected from the bilateral brain hemispheres of 20 patients with various brain diseases using 99mTc-HMPAO and from those of 20 patients using 99mTc-ECD. We also measured BPI using GA. The BPI values obtained by SA (BPIS) (x) and by GA (BPIG) (y) correlated closely (y=0.708x+0.038, r=0.945 for 99mTc-HMPAO and y=0.559x+0.093, r=0.931 for 99mTc-ECD). However, the BPIG values were underestimated by 22.9%±6.6% (mean±SD) for 99mTc-HMPAO and by 27.9%±7.5% for 99mTc-ECD as compared with the BPIS values. The extent of underestimation tended to increase with increasing BPIS values. These findings were considered to be a result of the BPIG values being affected by the first-pass extraction fraction of the tracer. We also compared the BPIS and BPIG values with those of CBF measured using N-isopropyl-p-[123I]iodoamphetamine (CBFIMP) in 16 patients (six for 99mTc-HMPAO and ten for 99mTc-ECD). Although both BPIS and BPIG values correlated significantly with the CBFIMP values, the correlation coefficient in BPIS was always better than that in BPIG (r=0.869 for 99mTc-HMPAO and r=0.929 for 99mTc-ECD in BPIS, r=0.629 for 99mTc-HMPAO and r=0.856 for 99mTc-ECD in BPIG). These results suggest that SA can provide a more reliable BPI for quantifying CBF using 99mTc-HMPAO or 99mTc-ECD than the conventional method using GA. Our method will be useful especially when using a tracer with a low first-pass extraction fraction and/or when performing activation studies using pharmacological intervention.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002590050591
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    MR arthrography of elbow: evaluation of the ulnar collateral ligament of elbow (1996)
    Springer
    Skeletal radiology 25 (1996), S. 629-634 
    Details
    ISSN: 1432-2161
    Keywords: Key words Elbow ; Ulnar collateral ligament ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Objective. The purpose of this study was to evaluate ulnar collateral ligament (UCL) injury of the elbow in throwing athletes by MRI and MR arthrography. Design. Ten elbows of throwing athletes were examined on both plain MRI and MR saline arthrography and the injuries subsequently surgically proven. Spin-echo (SE) T1-weighted and fast SE T2-weighted coronal images were obtained. Results. The UCL was unclear in all ten cases on T1-weighted MRI. In five cases an avulsion fracture was also found on T1-weighted MRI. On T2-weighted MRI, abnormal high-intensity areas were identified in or around the UCL. On T2-weighted MR arthrography images, extracapsular high-intensity areas, which represent extracapsular leakage, were found in four of five cases with avulsion fracture. At surgery, all these four cases showed avulsion fractures with instability; the other case had a fracture but it was stable and adherent to the humerus. On T2-weighted MR arthrography images, an extracapsular high-intensity area was found in one of the five cases without avulsion fracture. At surgery this patient had a complete tear of the UCL itself. Conclusion. MR arthrography provided additional information for evaluating the degree of UCL injury.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002560050149
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Mediastinal ultrasonography for the assessment of mediastinal lymph node metastases in lung cancer patients (1994)
    Springer
    Surgery today 24 (1994), S. 106-111 
    Details
    ISSN: 1436-2813
    Keywords: lung cancer ; ultrasonography ; mediastinoscopy ; computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using an ultrasonic probe inserted into the mediastinum during cervical mediastinoscopy, mediastinal ultrasonography (USM) was performed on 63 patients with lung cancer. The patients with a small peripheral mass of less than 2 cm in diameter, according to the chest X-ray results, and with mediastinal lymph nodes smaller than 1 cm in their short axes as determined by computed tomography (CT), were excluded from this study. An analysis of the areas under the receiver operating characteristic curves derived from CT and USM showed that USM was superior (P=0.043) to CT in terms of the diagnosis for mediastinal lymph node metastases, when the short axis dimension of mediastinal lymph nodes was employed for the diagnosis of metastases. The reason for this is that 97% of the mediastinal lymph nodes imaged by USM were located vertically along the body axis of the patient, and hence USM imaged the true short axis of the node in many cases. Our results indicate that USM is useful for performing a safe biopsy of lymph nodes during mediastinoscopy as well as for obtaining a clear imaging of the subcarinal nodes, which are inaccessible by normal cervical mediastinoscopy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02473390
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    Paper (German National Licenses)
    Fulltext
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