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  • 1
    Electronic Resource
    Electronic Resource
    Epitope mapping and characterization of monoclonal antibodies to human protein C
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular 1161 (1993), S. 113-123 
    Details
    ISSN: 0167-4838
    Keywords: Blood coagulation ; Epitope mapping ; Monoclonal antibody ; Protein C
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-4838(93)90204-5
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Two autopsy cases with Pelizaeus-Merzbacher disease phenotype of adult onset, without mutation of proteolipid protein gene (2000)
    Springer
    Acta neuropathologica 99 (2000), S. 7-13 
    Details
    ISSN: 1432-0533
    Keywords: Key words Adult ; Myelin ; Pathology ; Pelizaeus-Merzbacher disease ; Proteolipid protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the autopsy cases of two brothers which are pathologically compatible with Pelizaeus-Merzbacher disease (PMD). Both patients had a late onset (at the ages of 29 and 42 years) and chronic neurological symptoms including tremor, ataxia and dementia. The T2-weighted magnetic resonance imaging of the younger brother demonstrated increased signal areas with sparing of small areas in the cerebral white matter. The postmortem examinations, obtained at the ages of 45 and 61 years, showed similar neuropathological findings. Histologically, a cardinal finding was a lack of myelin in large parts of white matter with the preservation of islands of intact myelin, resulting in a “tigroid” appearance. Only small amounts of sudanophilic material were present. The axons were relatively well preserved, but oligodendrocytes were numerically reduced. Ultrastructurally, myelin sheaths in the white matter were markedly thin. Immunohistochemistry showed that proteolipid protein (PLP) was reduced in the affected white matter. However, genetic studies did not reveal exonic mutations or duplications of the PLP gene. We conclude that the two cases are a rare type of dysmyelinating disorder with PMD phenotype of adult onset and could be caused by previously unrecognized abnormalities of the PLP gene or other genes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00007409
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Active site for hydrogenation on reduced V2O5/Al2O3 catalyst (1991)
    Springer
    Reaction kinetics and catalysis letters 43 (1991), S. 481-486 
    Details
    ISSN: 1588-2837
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Abstract Активные центры гидрогенизации C2H4, образующиеся при восстановлении катализатора V2O5/Al2O3, предварительно обработанного при 450°C, содержат как сильно кислые льюисовские центры, так и основные центры Al2O3. Полагали, что на центрах льюисовской кислоты с силой, превышающей необходимую для гидрогенизации, конкурентно протекает полимеризация C2H4.
    Notes: Abstract Active sites for C2H4 hydrogenation produced by reduction of V2O5/Al2O3 catalyst pretreated at 450°C were found to be composed of both strong Lewis acid sites associated with V4+ and basic sites of Al2O3. C2H4 polymerization concurrent with hydrogenation was assumed to occur on Lewis acid sites with higher acid strengths than those of the hydrogenation sites.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02064716
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    Paper (German National Licenses)
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