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  • 1
    Electronic Resource
    Electronic Resource
    Development of a new modular titanium femoral prosthesis consisting of a head and shaft component. Indications, operation and optimization of the tapered socket connection (1999)
    Springer
    European journal of orthopaedic surgery & traumatology 9 (1999), S. 13-18 
    Details
    ISSN: 1432-1068
    Keywords: Modular femoral prosthesis ; Fretting ; Taper socket ; Cementless
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs décrivent une nouvelle prothèse fémorale modulaire associant une prothèse conventionnelle et un clou centro-médullaire. La prothèse est constituée d’une pièce céphalique et d’une partie diaphysaire fixées ensemble par un cône morse. Chaque pièce est modulaire selon les besoins en longueur et en diamètre. L’antéversion de la pièce céphalique est libre. Les pièces diaphysaires ont une courbure sagittale anatomique et sont creuses, permettant l’utilisation d’un guide centro-médullaire. Les pièces diaphysaires longues peuvent être verrouillées. Les pièces céphalique et diaphysaire sont en alliage de titane et la pièce diaphysaire a une surface grenaillée dans sa partie proximale. Le cône morse a été optimisé par l’adjonction d’une rainure qui a diminué l’usure par abrasion lors des tests de fatigue. Aucun démontage de la jonction intraprothétique et aucune fracture dé tige n’a été rencontrée lors de c es tests. La technique opératoire n’offre aucune particularité. Cent vingtquatre prothèses ont été implantées depuis 1990, principalement pour des fractures du col fémoral et des changements de prothèses totales de hanche. Les résultats cliniques sont en cours d’investigation. D’autres indications plus rares ont été choisies : pseudarthrose per-trochantérienne, fracture sur coxarthrose, chirurgie métastatique. Cette prothèse permet un ancrage diaphysaire stable dans les pertes de substance de l’extrémité supérieure du fémur, et autorise ainsi la repousse osseuse dans cette zone, spontanée ou après greffe osseuse, et la fixation proximale secondaire. L’optimisation du cône morse a permis de diminuer de façon considérable l’usure par abrasion. La modularité de la prothèse permet de s’adapter à toutes les morphologies et toutes les situations cliniques.
    Notes: Summary The development and clinical indications of a new modular femoral endoprosthesis consisting of a head and shaft component is discribed. Components are available in different lengths and diameters and therefore can be joined individually depending on the patients anatomy and surgery required. Both parts are joined by a unique optimized taper socket with a groove, avoiding fretting and corosion. Fatigue tests showed no loosening of the tapered connection and no prosthesis fracture. The advantage of this new modular prosthesis is diaphyseal stabilization, if necessairy by two distal interlocking screwes. Indications are revisions, pertrochanteric femoral and neoplastic fractures if cementless bridging of boney defects in the calcar region must be achieved. Further indications are femoral neck fraktures and coxarthrosis if stable diaphyseal fixation is required. The material and surface structure as well as the philosophie of the distal fixation are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02427763
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  • 2
    Electronic Resource
    Electronic Resource
    Relationships between the thyroid and somatotropic axes in steers II: Effects of thyroid status on plasma concentrations of insulin-like growth factor I (IGF-I) and the IGF-I response to growth hormone
    Amsterdam : Elsevier
    Domestic Animal Endocrinology 10 (1993), S. 71-85 
    Details
    ISSN: 0739-7240
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0739-7240(93)90013-2
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  • 3
    Electronic Resource
    Electronic Resource
    Influence of thyroid status regulation and Synovex-S^R implants on growth performance and tissue gain in beef steers
    Amsterdam : Elsevier
    Domestic Animal Endocrinology 9 (1992), S. 173-180 
    Details
    ISSN: 0739-7240
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0739-7240(92)90030-2
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  • 4
    Electronic Resource
    Electronic Resource
    Extrathyroidal thyroxine-5'-monodeiodinase activity in cattle
    Amsterdam : Elsevier
    Domestic Animal Endocrinology 1 (1984), S. 279-290 
    Details
    ISSN: 0739-7240
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0739-7240(84)90014-6
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  • 5
    Electronic Resource
    Electronic Resource
    Evidence that bovine growth hormone treatment increases the rate of extrathyroidal 5'-monodeiodinase activity in cattle
    Amsterdam : Elsevier
    Domestic Animal Endocrinology 7 (1990), S. 125-134 
    Details
    ISSN: 0739-7240
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0739-7240(90)90019-V
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  • 6
    Electronic Resource
    Electronic Resource
    High rate of post-therapeutic resistance after failure of macrolide–nitroimidazole triple therapy to cure Helicobacter pylori infection: impact of two second-line therapies in a randomized study (2002)
    Oxford UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 16 (2002), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The optimal second-line treatment after failed Helicobacter pylori therapy has not been established.〈section xml:id="abs1-2"〉〈title type="main"〉Aims:To ascertain whether quadruple therapy or triple therapy with omeprazole, clarithromycin and amoxicillin is the superior re-treatment after triple therapy containing a macrolide and a nitroimidazole, and to determine the impact of microbial in vitro resistance.〈section xml:id="abs1-3"〉〈title type="main"〉Methods:Patients after failed triple therapy were randomly allocated to one of two 1-week second-line treatments: omeprazole, 40 mg, clarithromycin, 500 mg, and amoxicillin, 1 g, all b.d.; or omeprazole, 20 mg b.d., bismuth subsalicylate, 600 mg q.d.s., metronidazole, 400 mg t.d.s., and tetracycline, 500 mg q.d.s. Post-therapeutic Helicobacter pylori status was assessed by 13C-urea breath test at least 4 weeks after treatment.〈section xml:id="abs1-4"〉〈title type="main"〉Results:The study was terminated after including 84 patients. H. pylori cure rates differed significantly: omeprazole–clarithromycin–amoxicillin: intention-to-treat, 43%; per protocol, 50%; omeprazole–bismuth subsalicylate–metronidazole–tetracycline: intention-to-treat, 68%; per protocol, 69%. The frequencies of resistance after first-line therapy were: metronidazole, 90%; clarithromycin, 71%; both combined, 68%. For clarithromycin resistance, H. pylori cure with omeprazole–clarithromycin–amoxicillin was 30% vs. 83% for clarithromycin susceptibility.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusions:Omeprazole–bismuth subsalicylate–metron- idazole–tetracycline was superior to omeprazole–clarithromycin–amoxicillin, but both therapies yielded unsatisfactory results. The high rate of post-therapeutic dual resistance has a negative impact on omepraz- ole–clarithromycin–amoxicillin, and probably also on omeprazole–bismuth subsalicylate–metronidazole–tetracycline, and limits the choice for second-line treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2002.01173.x
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  • 7
    Electronic Resource
    Electronic Resource
    Antigen stool test for assessment of Helicobacter pylori infection in patients with upper gastrointestinal bleeding (2003)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 17 (2003), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : Re-bleeding of Helicobacter pylori-associated peptic ulcer disease is reduced by H. pylori eradication.Aim : To validate a non-invasive test, the Premium Platinum HpSA™ stool test, in patients with upper gastrointestinal bleeding.Methods : Stool samples of consecutive patients with relevant bleeding from gastric or duodenal ulcers or erosions were collected at initial endoscopy and during the following week. Samples were assessed using the HpSA™ test. H. pylori status was defined by three biopsy-based reference methods: culture, rapid urease test and histology. It was positive if culture was positive or if rapid urease test and histology were positive.Results : One hundred and fourteen patients (mean age, 66 years) were included. In accordance with the definition, 56 (49%) were H. pylori positive. The sensitivity and specificity of the first stool sample were 84% and 90%, respectively. The respective values for two samples from consecutive days were 91% and 86%. In comparison with a serum immunoglobulin G antibody enzyme-linked immunoabsorbent assay, the HpSA™ test showed superior specificity.Conclusions : The diagnostic accuracy, in particular the sensitivity, of the HpSA™ stool test is reduced by upper gastrointestinal bleeding. The positive predictive value of 89%, however, justifies the initiation of eradication therapy on the basis of a positive stool test. A negative test result should be confirmed by a further diagnostic method.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2003.01548.x
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  • 8
    Electronic Resource
    Electronic Resource
    Thoracoscopic enucleation of benign tumors of the esophagus under simultaneous flexible esophagoscopy (2000)
    Springer
    Surgical endoscopy and other interventional techniques 14 (2000), S. 1146-1148 
    Details
    ISSN: 1432-2218
    Keywords: Key words: Esophageal tumor — Thoracoscopy — Esophagoscopy — Benign tumor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Benign tumors of the esophagus are very rare, accounting for only 0.1–2% of all esophageal tumors. Conventional treatment consists of thoracotomy adapted to the location of the tumor, followed by enucleation of the lesion. This approach, however, involves major surgery. Minimally invasive surgery represents a viable therapeutic alternative, in particular for benign tumors. Methods: In four patients with a benign tumor of the esophagus, we carried out thoracoscopic enucleation under simultaneous esophagoscopy. Results: Using this combination of endoscopic procedures, the tumors were removed reliably and safely. Two of the lesions were intramural leiomyomas, and two were intramural myxoid cysts. Conclusion: This combination of endoscopic procedures represents a minimally invasive approach with correspondingly minor surgical trauma. Using simultaneous esophagoscopy and transillumination (diaphanoscopy) of the esophageal wall, the safety and accuracy of the dissection is increased, and the risk of mucosal perforation minimized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004640000258
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  • 9
    Electronic Resource
    Electronic Resource
    The interface of laser-deposited Fe/Ag multilayers: evidence for the “subsurface growth mode” during pulsed-laser deposition and examination of the bcc–fcc transformation (1999)
    Springer
    Applied physics 69 (1999), S. S459 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 81.15.Fg; 68.55.-a; 68.35.Rh
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. One of the most significant features of pulsed-laser deposition (PLD) in vacuum as compared to conventional deposition methods is that a significant number of ions are deposited with a high kinetic energy of about 100 eV. Using Fe/Ag multilayers, we show that the deposition of energetic particles during PLD leads to implantation into the existing film. The film growth can be described by a growth mode in which the material does not grow on top, but rather within the topmost few monolayers of the already deposited film. To examine this “subsurface growth”, in situ resistance measurements and electron diffraction experiments were performed. Resistance measurements show a drop in conductance after beginning a new Fe layer, an effect attributed to implantation and alloying at the interface. Electron diffraction experiments allow the observation of the structural change from fcc-Ag to bcc-Fe and vice versa. These experiments are interpreted by the use of a Bain transformation to describe a homogeneous transformation between the two structures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390051438
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  • 10
    Electronic Resource
    Electronic Resource
    Study of laser-deposited metallic thin films by a combination of high-resolution ex situ and time-resolved in situ experiments (1999)
    Springer
    Applied physics 69 (1999), S. S455 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 68.55.-a
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. Laser-deposited metallic alloys and multilayers were studied in detail by a combination of high-resolution ex situ and time-resolved in situ experiments. The purpose of these experiments is to better understand the special properties of laser-deposited metallic films in comparison with conventionally prepared thin films. During deposition, thickness, resistance, and electron diffraction (THEED) experiments show that the film surface is resputtered, local mixing at the interfaces of multilayers on a nanometre scale occurs, and metastable phases up to large film thicknesses are formed. After deposition, a compressive stress of 1–2 GPa was measured using four-circle diffractometry, and growth defects were observed on an atomic scale by electron microscopy (HRTEM) and field ion microscopy (FIM). The obtained structural details of the metallic films can be explained by an implantation model for the laser deposition process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390051437
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