Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Evaluation of risk factors for the development of nephropathy in patients with IDDM: insertion/deletion angiotensin converting enzyme gene polymorphism, hypertension and metabolic control (1997)
    Springer
    Diabetologia 40 (1997), S. 327-331 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Diabetic nephropathy ; risk factors ; ACE polymorphism ; glycaemic control ; hypertension.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Diabetic nephropathy represents a major complication in patients with insulin-dependent diabetes mellitus (IDDM). Intervention trials using angiotensin-converting enzyme (ACE) inhibitors have pointed towards the important pathogenetic role of the renin-angiotensin system. Recently an insertion/deletion (I/D) polymorphism for the gene encoding the ACE has been described, the deletion type being associated with higher plasma ACE levels. As the intrarenal renin-angiotensin system might also be activated in this setting, we determined the ACE genotype together with other risk factors for the development of diabetic nephropathy in 122 patients with IDDM from a single centre with (n = 63) and without (n = 59) nephropathy. Long-term glycaemic control was evaluated using mean HbA1c values from the last 10 years. The two patient group were comparable with regard to duration of diabetes and glycaemic control as assessed by current HbA1c values. However, mean long-term HbA1c values were significantly higher in patients with diabetic nephropathy as was systemic blood pressure. The DD genotype was more prevalent in patients with renal disease. In the subgroup of patients who had had diabetes for more than 20 years (n = 90), the DD genotype was even more frequent in patients with nephropathy, and blood pressure and long-term HbA1c values were also higher in patients with renal disease. Logistic regression analysis revealed long-term glycaemic control, blood pressure and the ACE genotype to be independent risk factors for the prevalence of diabetic nephropathy. [Diabetologia (1997) 40: 327–331]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250050682
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Pleurale und pulmonale Veränderungen im Rahmen der rheumatoiden Arthritis (1996)
    Springer
    Der Radiologe 36 (1996), S. 637-645 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Rheumatoide Arthritis ; Lungenveränderungen ; Thoraxröntgen ; Computertomographie ; Thorax ; Key words Rheumatoid arthritis ; Pulmonary alterations ; Radiography ; chest ; Computed tomography ; Thorax
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Pulmonary complications caused by rheumatoid arthritis are a clinically relevant aspect of this chronic arthropathy. Those complications can involve all parts of the thorax, including the lung parenchyma, the pleura, and the thoracic cage. The most common complications are necrobiotic nodules, pleural abnormalities, Caplan's syndrome, parenchymal fibrosis, bronchiolitis obliterans, and iatrogenic damage of lung the parenchyma. This article reviews pulmonary abnormalities induced by rheumatoid arthritis and their clinical and radiological findings. In addition, the role of different imaging modalities in the diagnostic work-up of pulmonary complications caused by rheumatoid arthritis is discussed.
    Notes: Zusammenfassung Lungenveränderungen im Rahmen der rheumatoiden Arthritis stellen einen klinisch bedeutsamen Aspekt dieser in Schüben verlaufenden chronischen Arthropathie dar. Die mit dem Bestehen einer rheumatoiden Arthritis verbundenen pulmonalen Veränderungen können alle anatomischen Teile des Lungenparenchyms, die Pleura sowie Teile des knöchernen Thorax betreffen. Die wichtigsten thorakalen Veränderungen im Rahmen der rheumatoiden Arthritis sind die nekrobiotischen Rheumaknoten, pleurale Veränderungen, das Caplan-Syndrom, die Lungenfibrose, die Bronchiolitis obliterans und medikamentös induzierte Lungenveränderungen. Der vorliegende Artikel beschreibt das Spektrum der Lungenveränderungen, die im Rahmen der rheumatoiden Arthritis vorkommen. Hierbei werden die klinischen und radiologischen Charakteristika dieser Veränderungen vorgestellt. Die Bedeutung der verschiedenen bildgebenden Methoden im diagnostischen Algorithmus wird diskutiert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050122
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...