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  • 1
    Electronic Resource
    Electronic Resource
    MR Imaging of Lhermitte-Duclos disease: report of two cases (1992)
    Springer
    European radiology 2 (1992), S. 269-2721 
    Details
    ISSN: 1432-1084
    Keywords: Brain neoplasm ; MR studies ; Magnetic resonance imaging ; Brain diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two cases of Lhermitte-Duclos of the cerebellum are presented. MRI was essential in the radiological diagnosis of both lesions by the demonstration, both on T1- and T2 weighted images of thickened cerebellar folia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00595844
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  • 2
    Electronic Resource
    Electronic Resource
    CT and MRI of lipomeningioma: case report and review of the literature (1994)
    Springer
    European radiology 4 (1994), S. 569-571 
    Details
    ISSN: 1432-1084
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A case of lipomeningioma, an uncommon variant of meningioma, is described. Typical radiological features of meningioma, such as broad implantation in the dura, strong contrast enhancement and dural tail were associated with characteristics pointing to fatty content: negative density (−80 HU) on CT as well as short T1 and T2 on MRI.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00226832
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    In vivo study of phagocytosis, intracellular survival and multiplication of Flavobacterium psychrophilum in rainbow trout, Oncorhynchus mykiss (Walbaum), spleen phagocytes (2001)
    Oxford UK : Blackwell Science Ltd
    Journal of fish diseases 24 (2001), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The intracellular behaviour of a Flavobacterium psychrophilum strain, ingested by spleen phagocytes of rainbow trout, Oncorhynchus mykiss, of different ages, was assessed in vivo. Three groups of rainbow trout weighing 1 g (aged 10 weeks), 25 g (aged 20 weeks) and 300 g (aged 15 months), respectively, were injected intraperitoneally with 1 × 106 cfu of a F. psychrophilum strain. It was found that only fry, aged 10 weeks, displayed clinical signs and suffered mortality. Bacteriological colony plating of different organs demonstrated that the spleen and to a lesser extent the kidney of only the fry were affected. The number of colony forming units per gram of spleen tissue increased with time. No bacteria were found in the trout aged 5 months and older. Light microscopical examination and epifluorescence microscopy revealed that the fry spleen phagocytes contained an increasing number of viable intracellular F. psychrophilum bacteria over time. Again, no bacteria were encountered in the phagocytes collected from older fish.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2761.2001.00322.x
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  • 4
    Electronic Resource
    Electronic Resource
    Further evidence for myelinated as well as unmyelinated fibre damage in a rat model of neuropathic pain (1992)
    Springer
    Experimental brain research 91 (1992), S. 73-78 
    Details
    ISSN: 1432-1106
    Keywords: Hyperalgesia ; Peripheral neuropathy ; Nerve histopathology ; Neuropathic pain ; Unmyelinated fibre ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A mononeuropathy, produced by ligation of the sciatic nerve in rats, has recently been proposed as an animal model of experimental pain and pain-related disorders (hyperalgesia and allodynia). We investigated quantitatively the morphological changes in myelinated and unmyelinated fibres of the sciatic nerves 2 weeks after ligation in rats exhibiting allodynia to thermal stimulation. There was a marked reduction in the number of large myelinated fibres distal to the ligature (711 ± 34 compared with 5315 ± 230 in normal nerves). We also found a significant loss of small myelinated fibres (2429 ± 109 compared with 3197 ± 308 in normal nerves), the remaining fibres of this type showing pathological properties. Finally, ultrastructural evidence of damage to unmyelinated fibres was found. The typical pattern of large clusters of normal unmyelinated axons was no longer present within most regions of the nerve. There was a significant reduction in the size of the unmyelinated fibres (0.41 μm ± 0.15 compared with 0.71 μm ± 0.08 in normal nerves), together with a twofold increase in their number per cluster. Hypotheses about the mechanism of thermal allodynia in this pain model therefore must take into account the fact that all fibre classes show pathological changes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00230014
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Extradural epidermoid tumor of the frontal bone (1991)
    Springer
    Neuroradiology 33 (1991), S. 349-351 
    Details
    ISSN: 1432-1920
    Keywords: Epidermoid cyst ; MR imaging ; Brain tumors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The radiologic findings in a case of an extradural diploic epidermoid tumor (ET) of the frontal bone, examined with plain X rays, CT and MRI, are reported. A head injury with traumatic inclusion of epidermis could have been the origin of the tumor. This report stresses the importance of the plain skull X ray in the diagnosis of extradural ET.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00587822
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  • 6
    Electronic Resource
    Electronic Resource
    Peripheral primitive neuroectodermal tumour of the cervix (2000)
    Springer
    Virchows Archiv 436 (2000), S. 68-73 
    Details
    ISSN: 1432-2307
    Keywords: Key words Cervix ; Peripheral primitive neuroectodermal tumour ; Ewing’s tumour pathology ; Immunohistochemistry ; Cytogenetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Peripheral primitive neuro-ectodermal tumours (PNET) of the cervix are very rare. Here, we report the clinical, pathological, immunohistochemical and genetic features of a case of a PNET located in the cervix. Hysterectomy revealed a cervical tumour. On microscopic examination, a vaguely lobular arrangement of uniformly appearing neoplastic cells, with round to oval nuclei, distinct nuclear membranes and a clear, moderately glycogen-rich cytoplasm was seen. Cells stained positive for LEU 7, S 100, monoclonal NSE and particularly for MIC2. Neurogenic differentiation was also seen by electron microscopic examination. The genetic hallmark of PNET, a 22q12 rearrangement was demonstrated by fluorescence in situ hybridisation experiments, supporting the diagnosis. Awareness of the existence of primary PNET of the cervix is important to avoid confusion with other tumours of the cervix.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00008201
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Neurovascular intact muscle transposition for anal sphincter repair (1995)
    Springer
    Diseases of the colon & rectum 38 (1995), S. 878-885 
    Details
    ISSN: 1530-0358
    Keywords: Dynamic anal sphincter repair ; Muscle fiber composition ; Muscle resting length ; Semitendinosus muscle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: To study muscle behavior for anal sphincter repair, radiologic, manometric, and histologic techniques in a dog animal model have been used. Special attention was given to the problem of resting length of the transposed muscle. METHODS: The semitendinosus muscle of the dog could be transposed successfully to create a new anal sphincter based on an intact neurovascular pedicle. The parallel-fibered muscle was split at its distal end and encircled around the anal canal. Manometry was performed intraoperatively and postoperatively. A sufficiently high basal and squeeze pressure had to be obtained intraoperatively to guarantee a final continent neosphincter. This could be realized by a progressive stretching of the muscle until maximum squeeze is reached. In one animal a pacemaker was implanted, and postoperatively a fixed sphincter stimulation protocol was started. Muscle biopsies of the normal anal sphincter and the neosphincter were taken. RESULTS: 1) Muscle transposition gave a high degree of continence in this experimental model, with a mean resting pressure of ±40 mmHg and a mean squeezing pressure of ±73 mmHg. 2) Electric stimulation of the neosphincter in one animal influenced the resting pressure but not the squeeze pressure. 3) Muscle fiber type composition changed toward a slow fiber type composition after transposition of the fast muscle and even more after stimulation. CONCLUSIONS: 1) Creation of a muscle cuff around the anal sphincter can substitute normal anal sphincter. 2) Adequate stretch of muscle fibers is essential for continence. 3) Electrical pacing helps preserve resting tension and subsequent continence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02049846
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    Paper (German National Licenses)
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