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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 132 (1985), S. 264-268 
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    International Journal of Radiation Applications & Instrumentation. Part 43 (1992), S. 1431-1435 
    ISSN: 0883-2889
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2307
    Keywords: Arginase ; Gastric cancer ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract High levels of arginase have been detected in gastric adenocarcinoma. To examine the hypothesis that this is due to macrophage infiltration into the tumour, we localized the cellular distribution of arginase by immunohistochemical staining. We examined gastric adenocarcinomas and their corresponding normal tissues (n=45), leiomyomas (n=2), leiomyosarcomas (n=3), human gastric adenocarcinoma cell lines (n=3), and benign gastric ulcers (n=4) by the avidin-biotin-peroxidase complex technique. Macrophages with strong arginase immunoreactivity were observed infiltrating both gastric normal and cancer tissues. No arginase immunoreactivity was observed in normal mucosal gland, muscular and serosal tissues or benign gastric ulcers. The immunoreactivity of arginase was positive but heterogeneous in most specimens of gastric adenocarcinoma (62.2%) and was absent from gastric intestinal metaplasia, leiomyomas and leiomyosarcomas. Among the 28 neoplasms with arginase immunoreactivity, scattered immunoreactivity was also noted in adjacent dysplastic glands in 12 (42.8%) specimens. Arginase immunoreactivity was observed in all three gastric cancer cell lines. Arginase is present in the cytoplasm but not in the nucleus. These data suggest that the high arginase levels in adenocarcinoma cancer tissues originate largely from cancer cells.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 355 (1981), S. 546-546 
    ISSN: 1435-2451
    Keywords: Gastroduodenal diseases in advanced age ; Alterschirurgie ; Magen ; Duodenal ; Erkrankungen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 116 über 80jährige Patienten mit gastroduodenalen Erkrankungen, davon 60 mit Carcinom und 43 mit Ulcus wurden behandelt. Bei 65% der Patienten mit Careinom und 97% mit Ulcus handelte es sich bereits um ein kompliziertes Krankheitsbild. über 80% der Carcinompatienten waren im fortgeschrittenen Stadium. Die längste Überlebenszeit bei Stadium I war über 10 Jahre und im Stadium 11 7 Jahre. Noteingriff wurde bei 44 Patienten vorwiegend Ulcuspatienten durchgeführt mit einer Letalität von 54,5%. 92% aller Patienten hatten Begleiterkrankungen. Die Letalität betrug bei mehr als 3 Begleiterkrankungen über 50%.
    Notes: Summary Of a total of 116 patients over 80 years old with gastroduodenal diseases, surgery was performed on 60 with carcinoma and 43 with ulcers; 65% of the patients with carcinomas and 97% with ulcers already had related complications. Over 80% of patients with carcinomas were in advanced stages. The longest survival time in stage I was over 10 years and in stage II, 7 years. Emergency operations were carried out on 44 patients, mostly those with an ulcer, with a mortality of 54.5%. Accompanying diseases were found in 92% of all patients. If there were more than three accompanying diseases, mortality increased to over 50%.
    Type of Medium: Electronic Resource
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