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  • 1
    Electronic Resource
    Electronic Resource
    Muscle spindles in rheumatoid arthritis (1979)
    Springer
    Virchows Archiv 382 (1979), S. 191-200 
    Details
    ISSN: 1432-2307
    Keywords: Rheumatoid arthritis ; Muscle spindles ; Neuromuscular spindles ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Ultrastructural features of muscle spindles were studied in biopsy material from 100 patients suffering from classical rheumatoid arthritis. Thickening of the outer capsule, increased amount of extracellular ground substance within the inner capsule, and marked thickening of the basement membrane of capillary blood vessels supplying the muscle spindles were observed. Chronic inflammatory cells and macrophages were present within the spindles. Changes affecting the intrafusal muscle fibres were also seen. They were manifest as atrophy and degeneration of the intrafusal muscle fibres, absence of the specialised junctional complexes, and of the intercellular bridges, microladders and satellite cells. It is suggested that the changes affecting the intrafusal muscle fibres are probably secondary. Damage to the myelinated nerves was present, while the sensory and motor nerve endings were well preserved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01102874
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Muscle changes in rheumatoid arthritis (1977)
    Springer
    Virchows Archiv 373 (1977), S. 267-278 
    Details
    ISSN: 1432-2307
    Keywords: Rheumatoid arthritis ; Muscle changes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Muscle changes were studied in biopsy material obtained from 100 patients suffering from classical rheumatoid arthritis. The abnormalities consisted of denervation atrophy of type II muscle fibres, degenerative changes in the sarcoplasm including presence of nemaline rods, and changes within the interstitium: namely perivascular nodular myositis, lymphocytic accumulations, different stages of vasculitis and abnormalities within the intramuscular nerves and muscle spindles. The muscles examined were always severely affected. It is considered that the simultaneous presence of these abnormalities is suggestive of rheumatoid arthritis. The importance of histochemical studies is emphasized. The literature concerning muscle changes in rheumatoid arthritis is reviewed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00432241
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Microshunt histology in telangiectasias (1999)
    Springer
    The international journal of angiology 8 (1999), S. 98-101 
    Details
    ISSN: 1615-5939
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Telangiectatic spiders occur in 10–14% of the population. Recently, the most widely accepted theory of their origin is perforator incompetence and venous hypertension. In spite of that, various authors have suggested that arteriovenous (AV) shunts may contribute their etiology. Based on this theory, continuous wave, Doppler-drived biopsies were taken for histological examination. A total of 132 telangiectatic subjects were examined and in 91 cases, pulsatile sound of a tiny artery was detected over the spider. In 18 of the positive cases, a 2.5×1.5 cm specimen was excised for histology. In 16 of them, AV microshunt could be proved. According to this result it may be that AV microshunts have a role in the etiology and complication of sclerotherapy of some telangiectatic spiders.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01616823
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    Paper (German National Licenses)
    Fulltext
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