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  • 1
    Electronic Resource
    Electronic Resource
    Effect of iron deficiency anaemia and its treatment on sulphadimidine absorption (1987)
    Springer
    European journal of clinical pharmacology 33 (1987), S. 323-325 
    Details
    ISSN: 1432-1041
    Keywords: iron deficiency anaemia ; sulphadimidine ; absorption ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effect of iron deficiency anaemia and its treatment on the absorption of sulphadimidine has been investigated in adult patients. The absorption judged by total % of the dose excreted in urine and Cmax, tmax, AUC and Kabs in plasma, was not significantly different before and after iron therapy or correction of anaemia. However, sulphadimidine absorption by the anaemic patients was significantly greater than in normals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00637571
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of iron deficiency anaemia and its treatment on single dose phenytoin bioavailability (1993)
    Springer
    European journal of clinical pharmacology 45 (1993), S. 387-388 
    Details
    ISSN: 1432-1041
    Keywords: Iron deficiency anaemia ; Phenytoin ; bioavailability ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Iron deficiency is a common nutritional deficiency, which leads to structural functional and enzymatic changes in the body that may affect the pharmacokinetics of drugs. The present study in 7 normal volunteers and 8 adult male patients with irondeficiency anaemia (IDA) was done to investigate the effect of iron deficiency and its treatment with total dose iron (TDI) on the bioavailability of a single dose of phenytoin. Phenytoin bioavailability was investigated before and 3 and 28 days after TDI. The bioavailability parameters Cmax, tmax, AUC and 2 h phenytoin concentrations were not significantly different in anaemic patients as compared to normal volunteers before or after treatment, except for an increase in tmax 28 days after TDI treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00265961
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Visual evoked potentials in ataxia telangiectasia (1985)
    Springer
    Journal of neurology 232 (1985), S. 172-174 
    Details
    ISSN: 1432-1459
    Keywords: Evoked potentials, visual ; Ataxia telangiectasia ; Friedreich's ataxia ; Optic nerve ; Visual pathway
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Pattern reversal visual evoked potentials (VEPs) elicited in four patients with ataxia telangiectasia revealed normal results in two and absent responses in two. The pathogenesis of the VEP abnormalities is discussed. It is surmised that the VEP changes reflect progressive degeneration of the nerve fibres in the anterior visual pathway, as in Friedreich's ataxia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00313896
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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