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  • 1
    Electronic Resource
    Electronic Resource
    Untersuchungen über die Hämostase uteriner Blutungen durch Protaminsulfat und Toluidinblau (1956)
    Springer
    Archives of gynecology and obstetrics 188 (1956), S. 123-133 
    Details
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Es wird über Therapieversuche mit den Heparinantagonisten Protaminsulfat und Toluidinblau bei uterinen Blutungen berichtet. Der hämostyptische Erfolg ist unabhängig vom Schleimhautbild der Uterusmucosa, ein hormoneller Effekt damit unwahrscheinlich. Dafür spricht unter anderem, daß sich durch Vorgabe der Medikamente vor der zu erwartenden Periode die Menstruationsblutung nicht unterdrücken ließ. Im Gegensatz zu den bisherigen Vorstellungen der Verhinderung einer vorhandenen Hyperheparinämie, die wir bei Menstruationen und uterinen Blutungen mit modernen gerinnungsphysiologischen Methoden nicht feststellen konnten, wird als Ursache der günstigen Wirkung eine Hemmung proteolytischer Vorgänge durch diese Stoffe in der Uterusmucosa angenommen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01007054
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  • 2
    Electronic Resource
    Electronic Resource
    Hemophilic arthropathy of the knee joint: static and dynamic Gd-DTPA — enhanced MRI (1995)
    Springer
    European radiology 5 (1995), S. 547-552 
    Details
    ISSN: 1432-1084
    Keywords: Hemophilia ; Knee joint ; Synovial proliferation ; MR studies ; Gadolinium ; Contrast enhancement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A total of 17 patients with hemophilic arthropathy of the knee joint were studied with static and dynamic MRI before and after an IV bolus injection of Gadolinium-DTPA (Gd-DTPA; 0.1 mmol/kg body weight). The T1-weighted spin-echo (SE) and gradient-echo (fast-field echo [FFE]) sequences were applied. The FFE sequences of eight consecutive scans carried out over a time interval of 160 s were used in order to determine the time to signal intensity (SI) curves of the synovial proliferations surrounding soft tissue, bone marrow, and joint effusion. After the administration of a contrast agent, synovial proliferations exhibited an increase on FFE and SE images of 47.7 % (SD ± 14.3 %) and 37.4 % (SD ± 11.2 %), respectively, whereas muscle and fatty tissue, tendons, bone marrow, and joint effusion revealed only a minor increase in SI. The gradient of SI (ratio SI/time) of pannus was 39.6 %/min (SD ± 7.7 %/min) and differed significantly (P 〈 0.001) from that of bone marrow, fatty tissue, muscle tissue, tendons, and joint effusion (P 〈 0.05). In contrast to synovial proliferations in rheumatoid arthritis, no differentiation between various pannus vascularities based on the degree of enhancement was possible. The Gd-DTPA-enhanced MRI studies delineate and quantify the synovial proliferations in hemophilic arthropathy. Dynamic studies in hemophilic arthropathy do not provide qualitative assessment of the inflammatory process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00208351
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  • 3
    Electronic Resource
    Electronic Resource
    A Simple Model for Describing the Nonlinear Transmission Dynamics of ZnS〈sub〉x〈/sub〉Se〈sub〉1-x〈/sub〉/ZnS〈sub〉y〈/sub〉Se〈sub〉1-y〈/sub〉(x〉y) Waveguide Structures (1995)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 182-184 (Feb. 1995), p. 231-234 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/01/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.182-184.231.pdf
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  • 4
    Electronic Resource
    Electronic Resource
    Buchbesprechungen (1990)
    Springer
    Journal of molecular medicine 68 (1990), S. 773-773 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01647247
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  • 5
    Electronic Resource
    Electronic Resource
    Fasziitis bei granulomatöser Myositis — eine atypische Manifestation einer Sarkoidose? (1990)
    Springer
    Journal of molecular medicine 68 (1990), S. 335-341 
    Details
    ISSN: 1432-1440
    Keywords: Fasciitis ; Granulomatous myositis ; Sarcoidosis ; Muscular imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report about two female patients with a histopathological proven granulomatous myositis associated with a fasciitis. One patient showed noncaseating granulomas in the muscle fascia. She suffered from symmetrical contractures of the digital flexors and ankles. The second patient showed uveitis and polyneuropathy, too. In addition, increased activities of the angiotensinconverting-enzyme and lysozyme in the sera suggested that both cases represent a new form of sarcoidosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01649028
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  • 6
    Electronic Resource
    Electronic Resource
    Magnetic resonance imaging of skeletal muscles in idiopathic inflammatory myopathies of adults (1994)
    Springer
    Journal of neurology 241 (1994), S. 306-314 
    Details
    ISSN: 1432-1459
    Keywords: Myositis ; Skeletal muscles ; Magnetic resonance imaging ; Creatine kinase ; Electromyography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The purpose of the study was to describe typical MRI findings in various types of idiopathic inflammatory myopathies in adulthood and to correlate the MRI with histopathological and electromyographic findings, and the serum creatine kinase (CK) activity. A third goal was to assess the diagnostic value of the use of gadolinium-DTPA (Gd-DTPA). Fifty-eight patients (35 women, 23 men), aged 21–83 years (median age 59 years), suffering from idiopathic myositides (13 with acute and 45 chronic diseases; 25 with polymyositis, 14 with dermatomyositis, 8 with granulomatous and 11 with inclusion body myositides) were examined with MRI. Seventeen of them received an intravenous infusion of Gd-DTPA. Histopathological and MRI findings of 21 muscles of 18 patients were compared. MRI of skeletal muscles showed abnormal signal intensities in 56 (96.6%) of the 58 patients. MRI abnormalities were found more often than elevated CK activity (P 〈 0.001). The hyperintensity of T2-weighted images was more conspicuous than on T1-weighted images in 26 (44.8%) patients, indicating oedema-like abnormalities. MRI of 50 (86.2%) patients showed fat replacement. In acute myositides, oedema-like abnormalities were more often visible and in muscle lipomatosis less often visible than in chronic diseases (P 〈 0.05 each). In dermatomyositis oedema-like abnormalities were more and lipomatosis less frequent than in the other types of myositis (P 〈 0.005) and correlated with the acuteness of the disease. In 3 of 17 patients in whom contrast-enhanced T1-weighted images were obtained in addition to plain T1- and T2-weighted images, T2-weighted images were more sensitive in the detection of oedema-like abnormalities than the contrast-enhanced T1-weighted images. In no patient was the opposite true. Thus, contrast-enhanced T1-weighted images did not provide more information than T2-weighted images. Nine patients with poly-, dermato- and inclusion body myositis showed clearly asymmetrical findings. Imaging of the thighs and legs was of similar sensitivity. The different types of myositides showed typical but not specific distributions of the mesenchymal abnormalities in MRI. The findings indicate that MRI of skeletal muscles in myositides can visualize the presence and distribution of oedema-like abnormalities and intramuscular lipomatosis and is suitable for the assessment of the chronicity and severity of the disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00868438
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  • 7
    Electronic Resource
    Electronic Resource
    Magnetic resonance imaging of normal and pathological white matter maturation (1988)
    Springer
    Pediatric radiology 18 (1988), S. 183-189 
    Details
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Fifty children between 3 months postnatal and 16 years of age were examined by means of a 1.5 T superconductive magnet, run at 0.35 and 1.0 T. The myelination was studied qualitatively and quantitatively (relaxation times, proton densities, image contrast). With increasing age, a decrease of T1 and proton density of white matter was found, which was complete at one year of age. In regions with a slow progression of myelination, gray/white matter contrast showed an increase up to the end of the first decade. Pathological white matter maturation was diagnosed either as an abnormal transformation of myelin (characterized by abnormal relaxation values), or as a deficient or delayed myelin formation (in comparison with age-matched controls).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02390391
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  • 8
    Electronic Resource
    Electronic Resource
    Sonography and MRI of experimental muscle injuries (1997)
    Springer
    Archives of orthopaedic and trauma surgery 116 (1997), S. 357-361 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract After sonographical examination with a 7.5-MHz linear array scanner, we created an experimental muscle injury of known sitze and location on 28 New Zealand white rabbits by stabbing them with a scalpel in the supraspinatus muscle. The changes in the healing process were followed and documented by sonography and magnetic resonance imaging (MRI) before and 2, 5, 11, 14, 36 and 64 days after injury. The changes in sonography and MRI followed a regular course. Ultrasound revealed an echo-poor area after injury with ever increasing echogenicity from the 14th day. Strong reflexes were found after 2 months. MRI showed few changes, only a slight increase of signal intensity, but a characteristic curve of calculated T2-times (a program of the MRI software). The interpretation of the sonographical picture in histopathological terms remained limited. The development of a hematoma and of fibrous scars can be followed up by sonography, but it is not possible to determine the point of time after injury very accurately. Nevertheless, sonography is a method of great value in the diagnosis of muscle injuries and, given certain limits, in the follow-up of the healing process, too. The significance of MRI can be increased by calculations with the implemented software, as in our study calculated T2-times produced a characteristic curve reflecting the shift of fluids after muscle injury.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00433990
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Sonography and MRI of experimental muscle injuries (1997)
    Springer
    Archives of orthopaedic and trauma surgery 116 (1997), S. 357-361 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract After sonographical examination with a 7.5-MHz linear array scanner, we created an experimental muscle injury of known sitze and location on 28 New Zealand white rabbits by stabbing them with a scalpel in the supraspinatus muscle. The changes in the healing process were followed and documented by sonography and magnetic resonance imaging (MRI) before and 2, 5, 11, 14, 36 and 64 days after injury. The changes in sonography and MRI followed a regular course. Ultrasound revealed an echo-poor area after injury with ever increasing echogenicity from the 14th day. Strong reflexes were found after 2 months. MRI showed few changes, only a slight increase of signal intensity, but a characteristic curve of calculated T2-times (a program of the MRI software). The interpretation of the sonographical picture in histopathological terms remained limited. The development of a hematoma and of fibrous scars can be followed up by sonography, but it is not possible to determine the point of time after injury very accurately. Nevertheless, sonography is a method of great value in the diagnosis of muscle injuries and, given certain limits, in the follow-up of the healing process, too. The significance of MRI can be increased by calculations with the implemented software, as in our study calculated T2-times produced a characteristic curve reflecting the shift of fluids after muscle injury.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00433990
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Changes of sonographic, magnetic resonance tomographic, electromyographic, and histopathologic findings within a 2-month period of examinations after experimental muscle denervation (1998)
    Springer
    Archives of orthopaedic and trauma surgery 117 (1998), S. 228-234 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study compares sonographical, histopathological, magnetic resonance imaging (MRI), and electromyographical (EMG) findings following acute muscle denervation. We performed an experimental denervation of the supraspinatus and infraspinatus muscles on 35 New Zealand white rabbits by segment resection of the suprascapular nerve. The sonographical appearance of the supraspinatus muscle was followed and documented at short time intervals within a 2-month follow-up period. The sonographical, histopathological, and MRI changes due to denervation suggest a regular pattern. Apart from the reduction of the muscle diameter, there were considerable sonographical signs of denervation with an increase of echointensity and inhomogenicity of echotexture that appeared on day 14 after injury, and progressed continuously with time. MRI revealed a remarkable increase in signal intensity 3 weeks after denervation and reproducible T2 times. Pathological spontaneous activity on EMG could also be detected from day 14 after injury. Conventional histopathological staining methods (H & E, NADH, ATPase, basic and acid phosphatase) confirmed denervation and absence of reinnervation. The first nonspecific histopathological changes were seen 11 days after denervation in the form of moderately atrophic fibers. Typical histopathological signs of denervation appeared 3 weeks after nerve dissection. In summary, EMG, ultrasound, MRI, and histopathology each showed first abnormalities after about 2 weeks. In addition to EMG, sonography and MRI can document the course of muscle atrophy and mesenchymal abnormalities in neurogenic muscle lesions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004020050234
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