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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 19 (2004), S. 0 
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The goal of this study was to compare the lateral inhibition and the habituation in the human auditory cortex, two important physiological effects during auditory processing that can be reliably measured by means of magnetoencephalography when recording auditory evoked fields. Applying 40-Hz amplitude-modulated stimuli allowed us to record simultaneously the slow transient evoked and the steady-state fields and thus to characterize the lateral inhibition and the habituation effect in primary and non-primary auditory cortical structures. The main finding of the study is that the lateral inhibition effect of non-primary auditory areas as measured on the major component of the slow transient auditory evoked field (N1) is significantly stronger than the corresponding habituation effect. By contrast, this effect was not observed for the 40-Hz steady-state fields, characterizing the activation of the primary auditory cortex in humans. The results might be interpreted as (i) evidence that the inhibition mediated by lateral connections is stronger than the habituation of excitatory neurons in the non-primary auditory cortex and (ii) the processing hierarchy in the human auditory cortex is demonstrated by the different behaviour of lateral inhibition and habituation in primary and non-primary auditory cortical structures.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 21 (2005), S. 0 
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The auditory evoked response is known to be changed by a preceding sound. In this study we investigated by means of magnetoencephalography how a preceding notch-filtered noise (NFN) with different bandwidths influences the human auditory evoked response elicited by the following test stimulus. We prepared white noise (WN) and four NFNs which were derived from WN by suppressing frequency regions around 1 kHz with 1/8-, 1/4-, 1/2- and 1-octave bandwidths. Stimulation for 3 s with this set of noises resulted in differences in responsiveness to a 1-kHz test tone presented 500 ms after the offset of the noises. The N1m response to the 1-kHz test tone stimulus was at a minimum when the preceding NFN had 1/4-octave stop-band frequencies as compared with 1/8-, 1/2- and 1-octave NFN and WN. This N1m decrement is explained by the imbalanced neural activities caused by habituation and lateral inhibition in the auditory system. The results contribute to understanding of the inhibitory system in the human auditory cortex.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0165-1781
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A brief telephone interview was used to obtain information about the amount of phantom-limb pain in 65 upper-limb ampu- tees. This information served as the sole basis for the selection of a representative sample of 13 subjects with widely varying degrees of ...
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1573-6792
    Keywords: High-temperature superconductor ; Thin-film ; SQUID ; Biomagnetism ; Diagnostics ; Magnetoencephalography ; Auditory evoked fields
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have developed high-critical-temperature radio-frequency Super conducting QUantum Interference Devices (SQUIDs) with step-edge grain-boundary Josephson junctions and large flux focusers. These planar devices were fabricated from epitaxial YBa2Cu3O7 films and operated in the magnetometer and first-order gradiometer configurations while immersed in liquid nitrogen. At the temperature of 77K, we have attained a magnetic field resolution for the magnetometer better than 200 fT/Hz1/2 down to less than 1 Hz, i.e., over the low signal frequency range important for medical diagnostics. The results to date show a high promise for biomagnetic diagnostics. For the first time, we recorded the evoked responses from human brains using a high-temperature magnetometer and a first-order electronic gradiometer channel simultaneously. These results were obtained in a magnetically shielded room. An improvement in the magnetic field resolution by another order of magnitude is possible and probable.
    Type of Medium: Electronic Resource
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