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  • 1
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. A multicentre trial was conducted to compare the efficacy and side-effects of an intramuscularly administered PGE2 analogue and vacuum aspiration in women with a delay of up to 21 days in the expected onset of menses. A total of 473 such women were randomly allocated to treatment with either 16-phenoxy-W-17, 18, 19, 20-tetranor PGE2 methyl sulfonylamide (three intramuscular injections of 0.5 mg at 3-h intervals) or vacuum aspiration, and the outcome of therapy assessed 1, 2 and 6–8 weeks later. Retrospective analysis of hCG levels indicated that 419 (88.6%) women had been pregnant at the time of treatment. With few exceptions, administration of the PGE2 analogue induced vaginal bleeding in both pregnant and non-pregnant women but the duration and subjectively perceived amount of bleeding were greater than after vacuum aspiration. Both treatments were equally effective. In pregnant women the overall frequency of complete abortion was 91% for prostaglandin treatment and 94% for vacuum aspiration. If non-pregnant women were included, the respective success rates (i.e. percentages of women not pregnant 2 weeks after treatment) were 92% and 95%. Gastrointestinal side-effects and lower abdominal pain requiring intramuscular analgesia were more common after prostaglandin therapy than following vacuum aspiration in both pregnant and non-pregnant women.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A single pessary containing 0·5 mg 16,16 dimethyl prostaglandin E2 p-benzaldehyde semicarbazone ester was used for cervical dilatation prior to vacuum aspiration in 124 first trimester nulliparae. Five hours after prostaglandin administration the cervix had dilated to 8 mm or more in 87 patients (70 per cent). The uterus was evacuated in these patients without mechanical dilatation of the cervix. In the remaining 37 patients the cervix had become soft and dilated 5 to 7 mm and further mechanical dilatation could be carried out easily. Side effects were minor and included vomiting in two patients, diarrhoea in one and transient pyrexia in two patients. There were no complications and no damage to the cervix or uterus during evacuation.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To determine the optimal dosage and dosing interval for the use of misoprostol administered vaginally for pre-operative cervical dilatation.Design Prospective double-blind randomised study.Setting Fertility Control Centre, National University Hospital, Singapore.Methods Women were randomly allocated to either the 200 μg or the 400 μg misoprostol group. Vacuum aspiration was performed at either three or four hours after the insertion of misoprostol tablets. Using Hegar's dilatator, degree of cervical dilatation before operation was measured. Other parameters assessed included the amount of additional dilatation required (if it was 〈 Hegar 8), pre-operative and intra-operative blood loss, and associated side effects.Results For the 200 μg misoprostol group, only seven (23.3%) achieved a dilatation of ≥ 8 mm compared with 29 women (96.7%) in the 400 μg misoprostol group. The odds ratio was 95.3 (95% CI 10.9–830.9) for 400 pg misoprostol for successful pre-operative cervical dilatation of ≥ 8 mm. The mean cervical dilatation for 400 μg and 200 μg misoprostol was 8.2 mm and 6.4 mm, respectively (P 〈 0.001). The use of 400 pg misoprostol with an evacuation interval of three hours appears to be the optimal dosage and evacuation time interval. Increasing the time interval beyond three hours did not confer any additional advantage on the rate of successful cervical dilatation but was instead associated with an increase in side effects such as vaginal bleeding, lower abdominal pain and the appearance of products of conception at the cervical os. However, besides vaginal bleeding, no significant differences in the frequency of these side effects were demonstrated.Conclusion This first report on the comparison of differing dosages and time intervals to determine the optimal dosage treatment schedule shows that the vaginal application of 400 μg misoprostol for at least three hours is optimal for pre-operative cervical dilatation before vacuum aspiration in first trimester nulliparae.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 106 (1999), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To determine the optimal evacuation time interval in the use of vaginal misoprostol for cervical priming before first trimester termination of pregnancy.Design Prospective double-blind randomised study.Setting Fertility Control Centre, National University Hospital, Singapore.Methods Sixty healthy nulliparous women requesting legal termination of pregnancy between 6 and 11 weeks of gestation were randomly allocated to either the 400 pg or 600 μg misoprostol group. Vacuum aspiration was performed after three hours in the 400 pg group and at the end of two hours in the women given 600 μg misoprostol. Using Hegar's dilator, degree of cervical dilatation before operation was measured. Other parameters assessed included the amount of additional dilatation required (if 〈 Hegar 8), pre-operative and intra-operative blood loss, and associated side effects.Results For the 600 pg group, only five women (16.7%) achieved a cervical dilatation of 2.8 nun, compared with 28 women (93.3%) in the 400 μg group. Using the 400 μg misoprostol group as a baseline, the odds ratio was 0.014 (95% CI 0.003–0.080) for 600 pg for successful pre-operative cervical dilatation of 2.8 mm. The mean cervical dilatation for 400 and 600 μg misoprostol was 8.1 mm and 6.6 mm, respectively (P 〈 0.001). Despite the shorter evacuation time interval of two hours, the 600 μg dose was associated with an increase in side effects such as vaginal bleeding, abdominal pain and a fever of 〉 38.°C. However, other than abdominal pain, no significant differences in the frequency of these side effects were shown.Conclusion Use of 400 μg misoprostol with a minimal evacuation time interval of three hours still appears the optimal dosage and evacuation time for cervical priming before fiist trimester termination of pregnancy.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 41 (1985), S. 1755-1758 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 51 (1995), S. 482-484 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1434-4475
    Keywords: Tetraazamacrocycles ; Cr(III), Fe(III) and Co(II) Complexes ; Magnetic measurements ; Diffuse reflectance spectra
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Kondensation von α-Diketonenen wie 2,3-Butandion oder Benzil mit 1,8-Diamino-3,6-diazaoctan in Gegenwart von Cr(III), Fe(III) und Co(II) resultiert in der Bildung von macrocyclischen Komplexen vom Typ [MLX2]X und [CoLX]X mit M=Cr(III), Fe(III), L=N4-Macrocyclus und X=NO 3 − oder Cl−. Die Komplexe wurden mittels Elementaranalyse, Leitfähigkeits-und magnetischen Messungen, Molekulargewichtsbestimmung und Infrarot- bzw. diffuser Reflexions-Spektren charakterisiert.
    Notes: Summary Template condensation of α-diketones such as 2,3-butanedione or benzil with 1,8-diamino-3,6-diazaoctane in the presence of Cr(III), Fe(III) and Co(II) results in the formation of macrocyclic complexes of the type [MLX2]X and [CoLX]X (where M=Cr(III), Fe(III), L=N4 macrocycle and X=NO 3 − or Cl−). The complexes have been characterized by elemental analyses, conductance and magnetic measurements, molecular weight determinations, infrared and diffuse reflectance spectral studies.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Monatshefte für Chemie 104 (1973), S. 1064-1070 
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Several newSchiff base derivatives of aluminium have been synthesized by the reaction of aluminium isopropoxide with theSchiff bases having the donor system, O−N−O. The reactions in 1∶1 and 2∶3 molar ratios [Al(OPr i)3:Schiff base] have yielded Al(OPr i)(SB) and Al2(SB)3 types of products [where SB−- represents the anion of theSchiff base andSBH2= (2-hydroxy-1-naphthylidene)-2-hydroxyethylamine, (2-hydroxy-1-naphthylidene)-3-hydroxy-1-propylamine, (2-hydroxy-1-naphthylidene)-1-hydroxy-sec.-butylamine and (o-hydroxyacetophenone)-3-hydroxy-1-propylimine, resp. In these resulting monoisopropoxy aluminiumSchiff base and dialuminium tris-Schiff base derivatives, the central aluminium atom appears to be penta-and tetracoordinated, resp., as indicated by their dimeric and monomeric states determined ebullioscopically. The infrared spectra of the resulting derivatives have also been recorded and tentative assignments have been made.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-0867
    Keywords: Liming ; B nutrition ; pea ; corn ; hot-water soluble B ; soil pH ; acid Alfisol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract A field experiment was conducted during 1986–87 on a sandy loam acid Alfisol of Barapani, Meghalaya, India to study the effect of liming on boron nutrition of pea and corn grown in a sequence. Lime and boron were applied to pea and their residual effect was studied on corn. Application of 1.5 kg B ha−1 significantly increased the pod and stover yield of pea. A sharp yield depression occurred at higher B rates. Liming accentuated B deficiency in the absence of B treatment and it cured toxicity arising from excess B supply. A combination of B at 1.5 kg ha−1 and lime at 3.0 t ha−1 was optimum for pea, but this level of B application was insufficient to meet B requirements of succeeding corn. With higher rates of B fertilization, the residual effect of B on corn yield was significant. Concentration of B in shoot, pod, grain and stover of crops increased with the rate of B application. With increasing liming rate, B concentration decreased. Addition of B increased the hot-water soluble B in soil. The availability of native and added B decreased sharply with increasing liming rate.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Plant cell, tissue and organ culture 1 (1981), S. 33-38 
    ISSN: 1573-5044
    Keywords: Bougainvillea ; clonal propagation ; shoot apex culture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Shoot apices ofBougainvillea glabra ‘Magnifica’ were induced to regenerate an average of ten shoots from their bases in response to BAP (0.5 mg/l) plus IAA (1.5 mg/l). All the isolated shoots from such cultures were rooted in a medium containing 0.1 mg/l each of IBA and 2,4,5-T and lacking BAP. Plantlets were then successfully grown in potted soil where they flowered normally.
    Type of Medium: Electronic Resource
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