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  • 1
    Electronic Resource
    Electronic Resource
    Reactions to Penicillamine: A Case of Cutis Laxa, Elastosis Perforans Serpiginosa and “Pseudo” Pseudoxanthoma (2005)
    Oxford, UK; Malden, USA : Blackwell Publishing Ltd/Inc.
    Journal of cutaneous pathology 32 (2005), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This patient was a 61-year-old white female who received several years of penicillamine therapy for the treatment of cystinuria. She subsequently developed penicillamine induced cutis laxa, elastosis perforans serpiginosa, and pseudoxanthoma elasticum like skin lesions. In addition, she suffered from numerous chronic bilateral lower extremity skin ulcerations. Her past medical history was also significant for end stage renal disease requiring hemodialysis and pulmonary fibrosis. She presented to the University of Miami Wound Care Center in 1/04 for treatment of her chronic ulcerations. On physical examination, the patient had multiple large hyperpigmented plaques with central ulcerations on her lower extremities. Some of the ulcers had overlying crust and others were covered with yellow fibrinous tissue. She also had generalized thickened, lax skin with multiple folds. On her neck, thighs, back and arms were violaceous, atrophic, serpiginous plaques with peripheral crusted erosions. A biopsy taken from the patients left thigh revealed dermal elastosis and the features of pseudo-pseudoxanthoma. Two additional biopsies taken from the left thigh demonstrated elastosis perforans serpiginosa. This case highlights multiple skin manifestations of penicillamine therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0303-6987.2005.320bw.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Cutaneous Rhizopus in an Immunosuppressed Patient (2005)
    Oxford, UK; Malden, USA : Blackwell Publishing Ltd/Inc.
    Journal of cutaneous pathology 32 (2005), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The patient is an eight-year-old white male with a prior history of a small bowel transplant secondary to gastroschisis and a history of chronic rejection. He was admitted to the hospital to rule out rejection of his second small bowel transplant. During the admission he developed painful erythematous plaques with necrosis and hemorrhagic bullae on his left knee and left neck. Dermatology was consulted and biopsies and tissue cultures were obtained. On H&E there were multiple thick walled non-septate hyphae and the GMS stain showed right angle irregular branching hyphae with an affinity for blood vessels. A further work-up for disseminated disease was negative. The patient was diagnosed with cutaneous mucormycosis. The patient underwent extensive surgical debridement and was started on Ambisone and treated for six months with resolution. Primary cutaneous mucormycosis is a rare opportunistic deep fungal infection. It is the most acute and fatal of all fungal infections. There are multiple associated conditions including immunosuppression. This disease can be controlled with early diagnosis and a combination treatment plan. There are only a few reported cases in the pediatric population.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0303-6987.2005.320fz.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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