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Cutaneous Rhizopus in an Immunosuppressed Patient (2005)

Ravis, S. ; Frankel, S. ; Elgart, G.

Oxford, UK; Malden, USA : Blackwell Publishing Ltd/Inc.

Journal of cutaneous pathology 32 (2005), S. 0

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ISSN: 1600-0560

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: The patient is an eight-year-old white male with a prior history of a small bowel transplant secondary to gastroschisis and a history of chronic rejection. He was admitted to the hospital to rule out rejection of his second small bowel transplant. During the admission he developed painful erythematous plaques with necrosis and hemorrhagic bullae on his left knee and left neck. Dermatology was consulted and biopsies and tissue cultures were obtained. On H&E there were multiple thick walled non-septate hyphae and the GMS stain showed right angle irregular branching hyphae with an affinity for blood vessels. A further work-up for disseminated disease was negative. The patient was diagnosed with cutaneous mucormycosis. The patient underwent extensive surgical debridement and was started on Ambisone and treated for six months with resolution. Primary cutaneous mucormycosis is a rare opportunistic deep fungal infection. It is the most acute and fatal of all fungal infections. There are multiple associated conditions including immunosuppression. This disease can be controlled with early diagnosis and a combination treatment plan. There are only a few reported cases in the pediatric population.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.0303-6987.2005.320fz.x

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