Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    In vivo studies on basement membrane synthesis in diabetic and nondiabetic rats (1982)
    Springer
    Research in experimental medicine 181 (1982), S. 245-251 
    Details
    ISSN: 1433-8580
    Keywords: Diabetes ; Glomeruli ; Basement membrane synthesis ; Collagen synthesis ; Glucose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In rats with chronic diabetes, the synthesis of glomerular basement membrane was investigated in vivo by injection of3H-proline. Compared to the nondiabetic controls, the basement membrane synthesis was markedly raised. The formation of hydroxyproline as parameter for the synthesis of the collagen portion of the basement membrane increased to a somewhat greater extent than the incorporation of3H-proline. Hydroxyproline formation and proline incorporation showed a close correlation with the blood sugar level in the diabetic rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851197
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Glomerular basement membrane synthesis and serum concentration of type IV collagen in streptozotocin-diabetic rats (1984)
    Springer
    Diabetologia 26 (1984), S. 150-154 
    Details
    ISSN: 1432-0428
    Keywords: Basement membrane synthesis ; type IV collagen ; 7S collagen ; diabetes ; streptozotocin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Glomerular basement membrane synthesis was measured in vivo in diabetic rats at various times after streptozotocin injection. Simultaneously the type IV collagen concentration in serum was determined by a radioimmunoassay specific for the terminal cross-linking domain, 7S collagen. Basement membrane collagen synthesis and the 7S collagen levels were markedly raised in diabetic animals 18–34 days after streptozotocin injection and showed a significant correlation. The results suggest that the amount of serum 7S collagen reflects increased basement membrane synthesis in a diabetic situation. Both basement membrane collagen synthesis and serum 7S collagen concentration also show a positive correlation with the blood glucose levels of diabetic rats. This indicates that the degree of metabolic dysregulation influences basement membrane synthesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00281124
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...