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  • 1
    Electronic Resource
    Electronic Resource
    Activité et agressivité chez des ouvrières deMyrmica laevinodis Nyl. (Hymenoptere, Formicides) modification en fonction du groupement et de l'expérience individuelle (1979)
    Springer
    Insectes sociaux 26 (1979), S. 354-363 
    Details
    ISSN: 1420-9098
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Summary 1- The behaviour of workers ofMyrmica laevinodis confronted by an intruder (a worker ofMyrmica ruginodis) varies from individual to individual in small groups. A certain proportion of workers (about 50%) do not respond, others (30%) approach the intruder without violence, the remaining (20%) react more or less violently. Successive tests showed an increase in violence whilst the proportion of ants that attacked the intruder changed little. 2- When the ants were rearranged into 4 groups according to their activity and aggressivity, the aggressivity (number of bites achieved) of individuals altered so that the percentage of aggressive workers resembled that in the original groups. 3- When the ants were restored to their original groups we observed (a) an increased level of aggressivity; (b) a tendency for an individual to retain the rank of aggressivity if adopted in (2), whilst a large pool of ants remained non-aggressive throughout.
    Notes: Resume 1- Face à un intrus (une ouvrière deMyrmica ruginodis), des ouvrières âgées deMyrmica laevinodis, vivant en petits groupes, ont un comportement qui varie d'un individu à l'autre. Une partie des animaux reste inactive (environ 50%) tandis que certains se déplacent vers l'intrus sans l'attaquer (30%) et d'autres attaquent plus ou moins violemment (20%). La répétition des tests provoque une augmentation de l'agressivité des attaquants alors que leur nombre ne varie pas. 2- Le regroupement des individus en fonction de leur activité et de leur agressivité entraîne une régulation de ces comportements tendant à faire apparaître dans chaque groupe les différents types d'individus précédemment caractérisés. Cette régulation s'accompagne d'un remaniement du classement des individus — basé sur le nombre de morsures — dans les groupes les plus agressifs. 3- Lors de la reconstitution des groupes initiaux, on note: a) un niveau d'agressivité élevé, qui se maintient au fil des tests; b) une tendance à la stabilisation des rangs adoptés par les animaux lors de leur regroupement (cf, 2 ci-dessus), tandis que demeure un pool important d'individus constamment non agressifs et donc stables.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02223554
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  • 2
    Electronic Resource
    Electronic Resource
    Der cytochemisch ermittelte Leukosetyp als prognostischer Parameter bei unreifzelligen Leukosen (1974)
    Springer
    Journal of molecular medicine 52 (1974), S. 134-137 
    Details
    ISSN: 1432-1440
    Keywords: Acute leukaemia ; classification ; effect of therapy ; prognosis ; Unreifzellige Leukosen ; Klassifizierung ; Therapieeffekt ; Prognose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Komplette Remissionen und Überlebenszeiten von 81 Patienten mit unreifzelligen (akuten) Leukosen wurden zwischen Gruppen, die nach cytochemischen Kriterien ermittelt worden waren, verglichen. Die Klassifizierung erfolgte nach den Ergebnissen von PAS-, Peroxydase-und Esterase-Reaktionen. Eine signifikant höhere Rate an kompletten Remissionen und längere Überlebenszeiten wurden bei den Leukosen vom PAS-Typ im Vergleich zu allen anderen Formen festgestellt. Bei Erwachsenen und Kindern unterschied sich dieser Leukosetyp in der Remissionsrate nicht. Hieraus wird die Forderung abgeleitet, daß Erwachsene mit Leukosen vom PAS-Typ dieselbe intensive Behandlung erfahren sollten wie Kinder.
    Notes: Summary 81 cases of acute leukaemia were classified according to cytochemical criteria. PAS, peroxidase and esterase reactions were used for classification. Rates of complete remissions and duration of survival after diagnosis in the different groups were compared. A significant higher rate of complete remissions and longer duration of survival was detected in PAS type leukaemias compared to all the other types in adults. There was no significant difference in the remission rates between PAS type leukaemias in children and adults treated for at least 7 days. These results lead to the conclusion that adults with this type of acute leukaemia should receive the same treatment as children do.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01620751
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  • 3
    Electronic Resource
    Electronic Resource
    Observations sur le développement larvaire de Nyctiphanes couchii (Crustacea: Euphausiacea) au laboratoire (1973)
    Springer
    Marine biology 22 (1973), S. 159-166 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Résumé 1. Les larves de Nyctiphanes couchii (Bell) ont été élevées au laboratoire, à partir des stades calyptopis II et III, en utilisant des régimes alimentaires animaux végétaux et mixtes. 2. N. couchii se nourrit par prédation et par filtration dès la phase calyptopis. 3. L'étude a permis de recueillir des informations sur l'ontogénèse des larves (développement des appendices, formation des photophores, réduction du nombre d'épines du telson). 4. La vitesse de croissance peut atteindre 0,13 mm par jour, en moyenne, dans les lots nourris de nauplii d'Artemia salina. 5. La durée du stade calyptopis III est de 3,7 jours, en moyenne, et celle des stades furcilia est généralement comprise entre 3 et 4 jours, sous nos conditions d'élevage. La durée des stades tend à s'allonger lorsque les larves vieillissent. 6. Les régimes alimentaires à base d'algues permettent une croissance plus faibe que les nauplii d'A. salina et provoquent und allongement des intermues et de l'ontogénèse. Un apport limité de nauplii d'A. salina produit des effects comparables.
    Notes: Abstract Larvae of Nyctiphanes couchii (Bell) were reared in the laboratory from the second and third calyptopis stages; they were fed animal, algal and mixed diets. Data are presented on larval morphology, growth and moulting rates. It is demonstrated that N. couchii is capable of filter-feeding and of capturing prey from the calyptopis phase onwards. The influence of diet on larval development is discussed: algal diets induce a slower growth rate than that achieved by feeding with Artemia salina nauplii alone, and increase the length of intermoult periods and of ontogenesis. A limited supply of A. salina nauplii has similar effects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00391779
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  • 4
    Electronic Resource
    Electronic Resource
    Observations sur le développement larvaire de Meganyctiphanes norvegica (Crustacea: Euphausiacea) au laboratoire (1974)
    Springer
    Marine biology 26 (1974), S. 45-56 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Larvae of Meganyctiphanes norvegica (M. Sars), caught with a plankton net, were reared in the laboratory from the calyptopis phase onwards, under different temperature and trophic conditions. Eyestalk ablation was performed on the first furciliae. Data are presented on growth, moulting rate and ontogenesis of the larvae as a function of the varying experimental conditions, and on larval morphology, pigmentation and diet. Recent modifications of larval nomenclature in euphausiids are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00389085
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  • 5
    Electronic Resource
    Electronic Resource
    Evidence that expression of SpαI/65 hereditary elliptocytosis is compounded by a genetic factor that is linked to the homologous α-spectrin allele (1990)
    Springer
    Human genetics 〈Berlin〉 85 (1990), S. 627-630 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Many cases of hereditary elliptocytosis (HE) result from mutated spectrin α-chains. It has repeatedly been observed that the amount of a mutant α-chain is different in various affected individuals, resulting in clinical pictures of variable severity. The different levels are thought to result from different percentages of the αspectrin allele in trans. Such percentages, in turn, could be under genetic control. We tested this hypothesis in a large Algerian family with SpαI/65 HE. In an informative sibship, we found three persons with a distinctly high level of expression of the SpαI/65 variant, suggesting the existence, in trans, of a low percentage α-allele. The α-spectrin gene haplotype associated with the latter was constantly − +−, based on the XbaI, PvuII and MspI polymorphic sites. In contrast, a basal level of expression of the SpαI/65 variant in the same sibship indicated, in trans, the existence of a normal percentage α-allele. The haplotype corresponding to this other α-allele was + − +. Study of another generation of the family showed, however, that the − + − haplotype could also be linked to a normal percentage α-allele. These results are consistent with the view that the expression level of αI/65 spectrin (and of other types of α-variants) is compounded by a genetic factor that is linked to the normal α-allele in trans. The low percentage allele itself remains silent in the simple heterozygous state.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00193587
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  • 6
    Electronic Resource
    Electronic Resource
    A Systematic investigation of the dc electrical conductivity of rare-earth doped ceria (1989)
    Springer
    Applied physics 49 (1989), S. 225-232 
    Details
    ISSN: 1432-0630
    Keywords: 66.30 ; 61.70 ; 82.45
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The dc electrical conductivity of rare-earth doped ceria has been measured as a function of temperature (300–600 K) and composition (0.05–15 mol% M2O3) on using the complex impedance technique. Five dopants have been selected, yttrium and the lanthanides Yb, Gd, Nd, and La. For all of them, the variations of the activation energy versus dopant concentration are similar and characterized by the existence of a minimum. This peculiar property can be understood if attractive interactions between immobile dopant ions and mobile oxygen vacancies are taken into account. From an analysis of the experimental results, it is concluded that this interaction extends at least to third or fourth nearest neighbors depending on the size and the electronic configuration of the dopant ion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00616848
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  • 7
    Electronic Resource
    Electronic Resource
    Pharmacokinetics and bioavailability of diacetolol, the main metabolite of acebutolol (1981)
    Springer
    European journal of clinical pharmacology 19 (1981), S. 287-292 
    Details
    ISSN: 1432-1041
    Keywords: diacetolol ; acebutolol ; bioavailability ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics and bioavailability of diacetolol, the principal metabolite of acebutolol, were studied in 6 healthy subjects. Plasma concentrations were determined following a single intravenous injection of diacetolol 100 mg and three oral doses of diacetolol 100, 400 and 800 mg, in random order. The average oral bioavailability of diacetolol was F: 0.302±0.052 (100 mg), 0.363±0.052 (400 mg) and 0.426±0.068 (800 mg); the differences are not significant. The mean plasma half-life of the terminal phase, 7.94±0.26 h after intravenous administration, was significantly higher than after oral administration 12.27±1.00 h (100 mg), 12.82±1.59 h (400 mg) and 13.05±1.22 h (800 mg) (p〈0.02 to 0.05); the mean urine half-lives of the terminal phase were not significantly different. Renal clearance of diacetolol 10.2±0.81·h−1 represented about two-thirds of total body clearance 15.9±1.21·h−1. The results suggest either a first-pass effect or incomplete absorption of diacetolol after oral administration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00562806
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  • 8
    Electronic Resource
    Electronic Resource
    Pharmacokinetics in man of acebutolol and hydrochlorothiazide as single agents and in combination (1983)
    Springer
    European journal of clinical pharmacology 24 (1983), S. 801-806 
    Details
    ISSN: 1432-1041
    Keywords: acebutolol ; hydrochlorothiazide ; kinetics ; drug combination ; interaction ; diacetolol ; healthy subjects ; renal clearance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of acebutolol and hydrochlorothiazide (HCT) alone or in combination were studied in 12 healthy subjects in a cross over study. Acebutolol and diacetolol (the main metabolite) in plasma and urine were determined by HPLC and hydrochlorothiazide by GLC. The main pharmacokinetic parameters of acebutolol did not differ significantly: AUC 4492±272 µg l−1 h given alone versus 4118±354 µg l−1 h with HCT, half-life (7,69±0,32 h vs 8,10±0,72 h) and renal clearance (13,1±0,5 lh−1 vs 13,8±0,9 lh−1), respectively. There was no difference in diacetolol pharmacokinetics. HCT values were not significantly different: AUC 784±48 µg l−1 h given alone and 720±42 µg l−1 h with acebutolol, t1/2 (4,79±0,37 h vs 4,73±0,43 h). The renal clearance was slightly higher when HCT was given with acebutolol (26,2±2,6 vs 20,3±2,11 h−1,p〈0,05). This increase, observed during the first four hours, was probably due to competition between the drugs for binding to red blood cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00607091
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  • 9
    Electronic Resource
    Electronic Resource
    Evaluation of energetic particle parameters in the near-Earth magnetotail derived from flux asymmetry observations (1998)
    Springer
    Annales geophysicae 16 (1998), S. 283-291 
    Details
    ISSN: 0992-7689
    Keywords: Flux asymmetry ; Net flux intensity ; GEOS 2 ; Energetic particles
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract The flux asymmetries measured by spectrometers on board spacecraft contain information on particle parameters. The net flux intensity (NFI) method provides a tool to evaluate these parameters. The NFI method is valid when both the spin period of the spacecraft and the time resolution of the particle spectrometers are much shorter than the characteristic time-scale of the particle flux variations. We apply the NFI analysis to the flux asymmetry measurements made by GEOS 2 at the nightside geosynchronous orbit in the late substorm growth phase. The cross-tail current of energetic ions, their pressure gradient and average drift velocity, as well as a field-aligned flows are investigated. Current disruption at substorm onset and the –convection surge” mechanism during dipolarization of the magnetic field are directly observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00585-998-0283-7
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  • 10
    Electronic Resource
    Electronic Resource
    ULF wave measurements onboard the Interball auroral probe (1998)
    Springer
    Annales geophysicae 16 (1998), S. 1105-1116 
    Details
    ISSN: 0992-7689
    Keywords: Magnetospheric physics ; Auroral phenomena ; Plasma waves and instabilities ; Interball Auroral probe
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract The IESP experiment implemented onboard the Interball auroral probe measures the six components (3B, 3E) of the waves in the ULF range: 0.1–10 Hz and from time to time 0–30 Hz. Two different kinds of waves have been observed in the auroral region at altitudes between 10 000 and 20 000 km: (1) electrostatic emissions which consist of quasi-monochromatic structures with frequencies above the oxygen gyrofrequency, superimposed on a wide band signal interpreted as a Doppler broadening, (2) electromagnetic wide band spectrum fluctuations. These emissions are interpreted as current-driven electromagnetic or electrostatic ion cyclotron waves. The electromagnetic/electrostatic character is controlled by the plasma parameter βi and by the O+ concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00585-998-1105-7
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