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Readiness to recover in adolescent anorexia nervosa: prediction of hospital admission (2005)

Ametller, L. ; Castro, J. ; Serrano, E. ; [et al.]

Oxford, UK : Blackwell Publishing

The @journal of child psychology and psychiatry 46 (2005), S. 0

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ISSN: 1469-7610

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine , Psychology

Notes: Objectives: To determine if motivation to change in anorexia nervosa during treatment is a predictor of hospitalisation in adolescent patients.Method: The Anorexia Nervosa Stages of Change Questionnaire (ANSOCQ), the Eating Disorders Inventory-2 (EDI-2) and the Beck Depression Inventory (BDI) were administered to a group of 70 anorexia nervosa patients (mean age 15.6 years). They were all receiving treatment at a specialised Eating Disorder Unit and were at different points in the treatment programme. Admission during 6–9 month follow-up was recorded in 63 of these patients who had been admitted to the Unit. The other 7 patients were contacted by phone to determine if they had been hospitalised in another unit during the follow-up period.Results: Patients who needed hospital admission during follow-up had higher mean scores at first evaluation on some of the EDI-2 scales and on the BDI, lower ANSOCQ scores and were more likely to have been outpatients at first evaluation. In the logistic regression analysis a low ANSOCQ score and being an outpatient at first evaluation were shown to be independent predictors of hospitalisation during follow-up.Conclusions: Low motivation to change, depressive symptomatology and some EDI-2 scales are related to the necessity of hospital admission in adolescent patients with anorexia nervosa.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1469-7610.2004.00360.x

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2

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Etiology and prevalence of subclinical mastitis in the Manchega sheep at mid-late lactation

de la Cruz, M. ; Serrano, E. ; Montoro, V. ; [et al.]

Amsterdam : Elsevier

Small Ruminant Research 14 (1994), S. 175-180

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ISSN: 0921-4488

Keywords: Etiology ; Prevalence ; Sheep ; Somatic cell ; Subclinical mastitis

Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1016/0921-4488(94)90108-2

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3

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Subharmonic instability taking into account higher harmonics (1994)

Serrano, E. ; Carrascosa, M. ; Agulló-López, F. ; [et al.]

Woodbury, NY : American Institute of Physics (AIP)

Applied Physics Letters 64 (1994), S. 658-660

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ISSN: 1077-3118

Source: AIP Digital Archive

Topics: Physics

Notes: It is shown that a large number of higher harmonics are needed for determining a region of subharmonic instability. For the examples calculated, the final result is qualitatively similar to that obtained considering only the imposed interference pattern.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.111080

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4

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Nasal nitric oxide is increased in allergic rhinitis (1997)

ARNAL, J.-F. ; DIDIER, A. ; RAMI, J. ; [et al.]

Oxford, UK : Blackwell Publishing Ltd

Clinical & experimental allergy 27 (1997), S. 0

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ISSN: 1365-2222

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Background Nitric oxide (NO) plays a major role in the regulation of vascular tone and in non-specific host defence. The epithelium in the paranasal sinuses was recently identified as the major site of NO production in the upper airways.Objective To investigate NO status in allergic rhinitis, we compared the NO concentration in the nasal cavities of control subjects (n= 19) and in patients with allergic rhinitis (n= 36) with symptoms (WS, n= 17) or without symptoms (WOS, n= 19) on the day of the test.Methods NO concentration was measured using a chemiluminescent analyser aspiring from each nasal cavity at a sampling flow rate of 0.7L/min, before and 10min after administration of a nasal vasoconstrictor.Results The mean NO concentration (± se) in the control was 235 ± 11 ppb and 225 ± 9 ppb in the right and left nostrils respectively, and was decreased by 14% and 12% by the nasal vasoconstrictor (P 〈 0.001). The NO concentration in patients with allergic rhinitis was significantly higher in the right and left nostrils (382 × 20 ppb and 396 ± 28 respectively, P 〈 0.0001 versus control). All WOS patients demonstrated normal or increased NO concentrations in both nostrils, whereas two WS patients showed decreased NO concentrations in the left nostril. Inhalation of a nasal vasoconstrictor increased NO concentration by 6% and 27% in the right and left nostrils respectively in WS patients.Conclusion Nasal NO concentration is increased in patients with allergic rhinitis. Interestingly, patients without symptoms on the day of the test also showed a clear-cut increase in nasal NO production, which could reflect a permanent inflammation of the sinus mucosa.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1365-2222.1997.tb00719.x

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5

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Prevalence of nasal polyposis in France: a cross-sectional, case–control study (2005)

Klossek, JM. ; Neukirch, F. ; Pribil, C. ; [et al.]

Oxford, UK : Munksgaard International Publishers

Allergy 60 (2005), S. 0

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ISSN: 1398-9995

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Background: The prevalence of nasal polyposis (NP) has never been established in France due to the lack of diagnostic tools for population-based studies.Methods: Using a recently validated questionnaire/algorithm (90% specificity and sensitivity) in a population-based random sample, the present cross-sectional, case–control study allowed to determine NP prevalence and describe the principal aspects of NP epidemiology. A total of 10 033 subjects (≥18 years) were screened. After identification of subjects with NP and those without, another questionnaire was submitted to NP patients only for further data collection. Controls were individuals without NP, matched by gender and age to NP patients.Results: Nasal polyposis prevalence was 2.11% (95% CI 1.83–2.39). NP patients (n = 212, 45% males) were aged 49.4 ± 17.6 years. No gender preponderance was observed, but NP tended to increase with age. Mean duration of nasal symptoms was 22.4 ± 15.7 years. Among the 145 patients having already seen a doctor for their symptoms, 77.2% have been referred to a specialist, and 18.6% had a diagnosis of NP. Rhinorrhoea was reported by 39.9% of NP patients, blocked nose by 30.8%, and anosmia by 28.9%. Only 6.9% reported facial discomfort while 24.6% complained about general discomfort. Most NP patients (61.3%) had a pharmacological treatment, a nasal spray for the major part (76.9%).Conclusion: The present study provides valuable and reliable information on NP epidemiology in France; the collected information are in accordance with most published international data.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1398-9995.2005.00688.x

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6

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Nasal nitric oxide, the guardian of paranasal sinuses, is paradoxically increased by high doses of intravenous glucocorticoids (2005)

Degano, B. ; Têtu, L. ; Serrano, E. ; [et al.]

Oxford, UK : Munksgaard International Publishers

Allergy 60 (2005), S. 0

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ISSN: 1398-9995

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Background: High concentrations of nitric oxide (NO) originating from a type-2 nitric oxide synthase (NOS2) located within the paranasal sinuses are measured in nasal air in man. NO is believed to play a central role in nonspecific defense of paranasal sinuses. Glucocorticoids (GCs), a therapeutic often used for a wide range of diseases, is known to strongly downregulate NOS2.Aims of the study: To investigate the effect of very high intravenous doses of GCs on nasal NO in man.Methods: Nasal NO was measured in 15 patients without any history of allergy or chronic airway disorder who were treated for 3 days with a daily dose of 1000 mg methylprednisolone for an exacerbation of multiple sclerosis. Nasal NO was also measured in 30 matched control subjects.Results: In control subjects, the maximal value of nasal NO [mean (SE)] was 233 (8) part per billion (ppb), and did not differ from patients with multiple sclerosis [maximum value: 219 (13) ppb; left nostril: 214 (12) ppb; right nostril: 215 (12) ppb]. After GCs treatment, nasal NO increased in patients [maximum value: 250 (13) ppb (P 〈 0.0001); left nostril: 249 (12) ppb (P 〈 0.0001); right nostril: 244 (13) ppb (P 〈 0.0001)].Conclusions: We conclude that GCs do not decrease but even increase nasal NO.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1398-9995.2005.00880.x

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How should nasal symptoms be investigated in asthma? A comparison of radiologic and endoscopic findings (2004)

Raherison, C. ; Montaudon, M. ; Stoll, D. ; [et al.]

Oxford, UK : Munksgaard International Publishers

Allergy 59 (2004), S. 0

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ISSN: 1398-9995

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Background: To improve asthma control, the management of rhinosinusitis often leads the physician to perform sinonasal imaging and/or nasal endoscopy, but their respective contributions are still insufficiently understood.Objective: To evaluate the potential contribution of a symptoms questionnaire, sinus radiography (SR) and computed tomography (CT) scan to the diagnosis of nasal diseases in asthmatic patients when compared with ENT examination.Methods: A total of 124 patients completed a questionnaire on nasal symptoms administered by the chest physician. Then, they underwent ENT examination. On the same day, SR and CT scans were performed independently.Results: Patients (80.3%) had nasal symptoms during the month preceding the consultation. The ENT examination was normal in 8.1% (n = 10) and revealed rhinitis in 57.3% (n = 71), rhinosinusitis in 14.5% (n = 18) and nasal polyposis in 20.2% (n = 25). For rhinitis, the negative predictive value of bilateral nasal obstruction was 87.8%. Both SR and CT had low sensitivity and specificity. For rhinosinusitis, the negative predictive value of nasal symptoms varied from 85.4 to 95.2%. Sinus CT was at least as accurate as SR for the diagnosis of rhinosinusitis. In a multivariate analysis, only the CT scan (score ≥12) appeared to be significantly associated with the diagnosis of nasal polyposis.Conclusion: In asthmatic patients, physicians need to enquire systematically about the existence of nasal symptoms by using this simple questionnaire which is sensitive for rhinitis, and has good negative predictive value for excluding rhinosinusitis and nasal polyposis.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1398-9995.2004.00487.x

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8

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Ossification of the Appendicular Skeleton in the Spanish Ibex Capra pyrenaica Schinz, 1838 (Artiodactyla: Bovidae), with Regard to Determination of Age (2004)

Serrano, E. ; Gállego, L. ; Pérez, J. M.

Berlin, Germany : Blackwell Verlag GmbH

Anatomia, histologia, embryologia 33 (2004), S. 0

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ISSN: 1439-0264

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: We studied ossification macroscopically in 35 Spanish ibex (Capra pyrenaica) appendicular skeletons in order to establish the skeletochronology in both sexes of the species. The age of animals had been determined by means of horn segment counts, teeth replacement and cementum layer counts from first incisors and ranged from 〈1 to 12 years. Females showed a faster ossification process than males. Moreover, for each age or year class considered, regarding both sexes, different stages of epiphyseal fusion could be found. Therefore, if we try to use data from bone remains in population studies (e.g. differential mortality rates), determination of the ossification stage for ageing bone samples must be carried out with caution.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1439-0264.2004.00506.x

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Effectiveness of ribosomal fractions ofKlebsiella pneumoniae, Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and the membrane fraction ofKp (Ribomunyl) in the prevention of clinical recurrences of infectious rhinitis (1997)

Serrano, E. ; Demanez, J. P. ; Morgon, A. ; [et al.]

Springer

European archives of oto-rhino-laryngology and head & neck 254 (1997), S. 372-375

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ISSN: 1434-4726

Keywords: Recurrent infectious rhinitis ; Treatment ; Immunostimulant ; Ribosomes

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract A multicenter, double-blind, placebo-controlled study was conducted to investigate the efficacy of an immunostimulant, Ribomunyl, in the prevention of recurrences of infectious rhinitis in adults. This trial involved 327 patients (168 Ribomunyl treated and 159 placebo cases) with an average of 4.3 ± 1.8 rhinitis episodes per patient recorded during the year preceding the study. The main criterion of efficacy was the cumulative number of recurrences of infectious rhinitis during a 6-month follow-up period, as analyzed by standard tests. An additional analysis of relative risk of recurrences used multivariate failure for time data. Ribomunyl was effective throughout the study period, starting from the first month of treatment: a mean of 1.0 ± 1.1 recurrences was recorded in the Ribomunyl group as compared to 1.5 ± 1.4 recurrences in the placebo group; this indicated one-third fewer infections (P = 0.001). The protective effect of Ribomunyl on the relative risk for recurrences was estimated to be 0.58 by multivariate analysis (95% CI: 0.43–0.78,P = 0.0001). Analysis of secondary criteria also favored Ribomunyl: 38.5% less antibiotic courses per patient (0.8 ± 1.3 vs 1.3 ± 1.6;P = 0.002) and the number of days with antibiotics (5.6 ± 9.3 vs 9.1 ± 12.1;P = 0.002).

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01642553

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Coloplasty and free intestinal transplants in the treatment of extensive cancers of the pharyngo-oesophageal junction (1989)

Pessey, J. -J. ; Fourtanier, G. ; Chavoin, J. -P. ; [et al.]

Springer

European archives of oto-rhino-laryngology and head & neck 246 (1989), S. 384-387

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ISSN: 1434-4726

Keywords: Circular pharyngolaryngectomy ; Oesophageal stripping ; Coloplasty ; Free intestinal transplant

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The authors report their surgical experiences with 55 extensive tumours of the pharyngoesophageal junction. Thirty-three of these cases were managed by circular pharyngolaryngectomy, total oesophagectomy with stripping and left coloplasty, and 22 were treated with circular pharyngolaryngectomy with free intestinal transplants. A comparative study of the post-operative courses of the patients and their oncological and functional outcomes shows the advantages, disadvantages and indications of these two techniques.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00463601

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