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  • 1
    Electronic Resource
    Electronic Resource
    Pallidonigroluysian degeneration with iron deposition: a study of three autopsy cases (1993)
    Springer
    Acta neuropathologica 86 (1993), S. 609-616 
    Details
    ISSN: 1432-0533
    Keywords: Symptomatic Parkinson's disease ; Pallidonigroluysian degeneration ; Basal ganglia ; Iron
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In the basal ganglia of three autopsy cases of pallidonigroluysian degeneration, we found marked iron deposition, a finding which has not been mentioned previously in the literature. Besides severe astrogliosis and neuronal loss in the pallidum, Luysian body and nigra, granular deposits of brown pigments were found in the neuropil, microglias, oligodendrocytes and astrocytes in three such the nuclei and the striatum. These brown pigments proved histochemically to be iron. Our histochemical semiquantitative study showed a significantly stronger reation for iron in the degenerated nuclei in these three cases than in control cases comprising non-degenerative and the other degenerative diseases. Quantitative study with inductively coupled emission spectrometry also demonstrated a markedly higher iron content in the globus pallidus and the striatum in comparison with the control cases. The possibility is discussed that iron deposition plays a role in generating the lesions of pallidonigroluysian degeneration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00294300
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  • 2
    Electronic Resource
    Electronic Resource
    Accelerator for ion beams using triangle-shaped accelerated waves (1986)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 57 (1986), S. 2935-2939 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: An accelerator for ion beams has been designed and constructed in which ions collectively undergo acceleration in the wells of a train of triangle-shaped potential waves moving with a constant acceleration. The accelerator mentioned above is planned for investigating the conditions necessary for acceleration of ions with a mass distribution, such as cluster ions, which will be available in future fusion reactors. The method and the circuits for generations of propagating accelerated waves are described and the structure of the accelerator with an acceleration space 120 cm long is mentioned. A result is reported on a preliminary experiment for acceleration of an argon ion beam, which shows that the accelerator works well.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1139020
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  • 3
    Electronic Resource
    Electronic Resource
    PLATELET-DERIVED GROWTH FACTOR B-CHAIN COMPRISES THE MAJOR PART OF ENHANCED RELEASED MITOGEN FROM AORTIC ENDOTHELIAL CELLS OF STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 22 (1995), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The present study was conducted to analyse the release and production of mitogen in cultured aortic endothelial cells of stroke-prone spontaneously hypertensive rats (SHRSP), for the further understanding of the role of arterial endothelial cells in the genesis of vascular lesions in hypertension.2. The cultured aortic endothelial cells derived from SHRSP increased released mitogens were compared with those from control Wistar-Kyoto rats (WKY) with respect to cultured vascular medial smooth muscle cells and fibroblasts.3. Biochemical analyses determined that the major part of mitogen released from aortic endothelial cells of both SHRSP and controls was the platelet-derived growth factor B-chain.4. Further northern analyses revealed that the transcripts of PDGF B-chain were constitutively accumulated three- to fourfold in quiescent aortic endothelial cells from SHRSP, compared with those from WKY through passages 2 to 5.5. However, the half-lives of the transcripts after actinomy cin D treatment were 1.12 h (s.d. = 0.14, n= 4) and 1.28 h (s.d. = 0.08, n= 3), in SHRSP and in WKY, respectively, showing no significant difference.6. These suggest that the increased accumulated transcripts of PDGF B-chain in SHRSP are due to an enhanced trans-criptional rate. These enhanced release and production of PDGF-B chain in arterial endothelial cells, which may be induced under chronic hypertensive conditions, is suggested to contribute to the genesis of vascular lesion in hypertension, through the stimulation of vascular smooth muscle cell proliferation and hypertrophy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1995.tb02848.x
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  • 4
    Electronic Resource
    Electronic Resource
    Phenylethanoid glycosides from Plantago depressa
    Amsterdam : Elsevier
    Phytochemistry 32 (1993), S. 975-977 
    Details
    ISSN: 0031-9422
    Keywords: Plantaginaceae ; Plantago depressa ; phenylethanoid glycosides ; β-oxoacteoside.
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0031-9422(93)85238-M
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  • 5
    Electronic Resource
    Electronic Resource
    Phenolic compounds from Plantago asiatica
    Amsterdam : Elsevier
    Phytochemistry 29 (1990), S. 3627-3631 
    Details
    ISSN: 0031-9422
    Keywords: Plantaginaceae ; Plantaginis Herba ; Plantago asiatica ; ^1^3C NMR ; enzyme inhibitory activity. ; hellicoside ; phenolic compound ; phenylpropanoid glycoside
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0031-9422(90)85289-R
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  • 6
    Electronic Resource
    Electronic Resource
    Viscous properties of calcium carbonate filled polymer melts (1979)
    Springer
    Rheologica acta 18 (1979), S. 635-639 
    Details
    ISSN: 1435-1528
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Zusammenfassung Es wurden die viskosen Eigenschaften von Polyäthylen-und Polystyrol-Schmelzen untersucht, die mit Kalziumkarbonat-Teilchen gefüllt waren. Für die relative Viskositätη r, wie sie in einer vorangegangenen Veröffentlichung definiert worden war, ergab sich bei Schubspannungen unterhalb 105 dyn/cm2 ein asymptotischer Wert(η r)l. Dieser war bei den mit Kalziumkarbonat gefüllten Schmelzen höher als bei Schmelzen, die bis zur gleichen Volumenkonzentrationφ mit Glaskugeln oder Glasballons gefüllt waren. Die (η r) l —φ-Abhängigkeit ließ sich durch eine Gleichung nachMaron und Pierce mitφ 0 = 0,44 beschreiben. Es wurde jedoch geschlossen, daß der hohe(η r)l-Wert der mit Kalziumkarbonat gefüllten Schmelzen auf eine scheinbare Zunahme vonφ zurückzuführen ist, verursacht durch eine feste Polymerschicht auf der Teilchenoberfläche. Unter Annahme kugelförmiger Teilchen mit einem Durchmesser von 2 µm ließ sich die zugeordnete Schichtdicke zu 0,17 µm abschätzen. Die mittels der Casson-Beziehung geschätzte Fließspannung ergab eine exponentielleφ-Abhängigkeit.
    Notes: Summary The viscous properties of calcium carbonate filled polyethylene and polystyrene melts were examined. The relative vircosityη r defined in the previous paper gave an asymtptotic value(η r)l in the range of the shear stress below 105 dyne/cm2.(η r)l of the calcium carbonate filled system was higher than that of the glass beads or glass balloons filled system at the same volume fraction of the fillerφ. Maron-Pierce equation withφ 0 = 0.44 was able to approximate the(η r)l — φ relationship. However, it was deduced here that the high value of(η r)l of calcium carbonyl filled system was due to the apparent increase ofφ and this increase was attributed to the fixed polymer layer formed on the powder particle. By assuming the particle as a sphere with a diameter of 2 µm, the thickness of the fixed polymer layer was estimated as about 0.17 µm. The yield stress estimated from the Casson's plots increased exponentially withφ.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01520361
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  • 7
    Electronic Resource
    Electronic Resource
    Viscosity of particle filled polymer melts (1978)
    Springer
    Rheologica acta 17 (1978), S. 149-155 
    Details
    ISSN: 1435-1528
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Zusammenfassung Viskositäten von Polymerschmelzen, die mit Teilchen gefüllt worden waren, wurden bei mittleren Schergeschwindigkeiten bestimmt. Als Teilchen wurden Voll- und Hohlkugeln aus Glas, sowie sog. „silas balloons“, als Polymere Polyäthylen und Polystyrol verwendet. Die Fließkurven für verschiedene Füllstoffkonzentrationen wurden überlagert. Die relative Viskosität, definiert als das Verhältnis der Viskositäten von gefülltem und ungefülltem Polymer bei gleicher Schubspannung, besitzt einen asymptotischen Wert selbst für hoch gefülltes Material. Die Beziehung zwischen relativer Viskosität und Füllstoff-Volumenkonzentration läßt sich durch eine vonMaron undPierce oder eine vonMooney abgeleitete Gleichung beschreiben. Nur die Teilchengrößenverteilung hat bei einer definierten Füllstoffkonzentration einen Einfluß auf die relative Viskosität. Fließspannungen werden abgeschätzt und dafür in einem Konzentrationsbereich zwischen 0,1 und 0,5 ein exponentieller Anstieg gefunden.
    Notes: Summary Viscosities of particle filled polymer melts were measured at fairly low shear rate. Particles were glass beads, glass balloons, and silas balloons. Polymers were polyethylene and polystyrene. Flow curves were superimposed with respect to concentration of filler. The relative viscosity defined as the ratio of viscosity of filled polymer to that of unfilled polymer at the same shear stress is obtained as an asymptotic value even for highly filled material. The relation between relative viscosity and volume fraction of filler was represented by the equations derived byMaron andPierce orMooney. Only the distribution of particle size had influence on relative viscosity at a defined filler concentration. Yield stresses were estimated, and found to increase exponentially in the range of volume fraction from 0.1 to 0.5.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01517705
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