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  • 1
    ISSN: 1432-0533
    Keywords: Key words Huntington's disease ; Human brain ; Thalamus ; Nuclei centromedianus-parafascicularis ; Neurone number
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The centromedian-parafascicular complex represents a nodal point in the neuronal loop comprising striatum – globulus pallidus – thalamus – striatum. Striatal neurone degeneration is a hallmark in Huntington's disease and we were interested in estimating total neurone and glial number in this thalamic nuclear complex. Serial 500-μm-thick gallocyanin-stained frontal sections of the left hemisphere from six cases of Huntington's disease patients (three females, three males) and six age- and sex-matched controls were investigated applying Cavalieri's principle and the optical disector. Mean neurone number in the controls was 646,952 ± 129,668 cells versus 291,763 ± 60,122 in Huntington's disease patients (Mann-Whitney U-test, P 〈 0.001). Total glial cell number (astrocytes, oligodendrocytes, microglia, and unclassifiable glial profiles) was higher in controls with 9,544,191 ± 3,028,944 versus 6,961,989 ± 2,241,543 in Huntington's disease patients (Mann-Whitney U-test, P 〈 0.021). Considerable increase of fibrous astroglia within the centromedian-parafascicular complex could be observed after Gallyas' impregnation. Most probably this cell type enhanced the numerical ratio between glial number and neurone number (glial index: Huntington's disease patients = 24.4 ± 8.1; controls = 15.0 ± 5.2; Mann-Whitney U-test, P 〈 0.013). The neurone number in the centromedian-parafascicular complex correlated negatively, although statistically not significantly, with the striatal neurone number. This lack of correlation between an 80% neuronal loss in the striatum and a 55% neurone loss in the centromedian-parafascicular complex points to viable neuronal circuits connecting the centromedian-parafascicular complex with cortical and subcortical regions that are less affected in Huntington's disease.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Studia geophysica et geodaetica 42 (1998), S. 224-231 
    ISSN: 1573-1626
    Keywords: dynamo ; geodynamo ; dynamo experiment ; mean-field dynamo theory ; α-effect
    Source: Springer Online Journal Archives 1860-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences , Physics
    Notes: Abstract At the Forschungszentrum Karlsruhe an experiment is in preparation which it is hoped, in view of the geodynamo and other cosmic dynamos, that a homogeneous dynamo will be demonstrated and investigated. This experiment is discussed within the framework of mean-field dynamo theory. Results are presented concerning kinematic cylindrical mean-field dynamo models reflecting some features of the experimental device, as well as results of detailed calculations of the α-effect that apply to arbitrarily high magnetic Reynolds numbers. On this basis estimates of the excitation conditions of the dynamo are given and predictions concerning the geometrical structure of the generated magnetic fields are made.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 565 (1988), S. 91-105 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Sulfur Dioxide as Ligand and Synton. VII. Phosphane Sulfur Dioxide Nickel (0) and Palladium (0) ComplexesSynthesis and properties of phosphane sulfur dioxid d10-metal complexes of the types ML2(SO2)2, ML2(SO2), and ML3(SO2) (M = Ni(0), Pd(0); L = t-phosphane) are described. In dependence on the phosphane coligands nickel(0) complexes with η1-planar, η1-pyramidal and η2-S.O. (side on) coordinated SO2 are formed. In the case of the palladium(0)-SO2 complexes hithero prepared the dominating coordination mode is the η1-pyramidal one.
    Notes: Synthese und Eigenschaften von Phosphan-Schwefeldioxid-d10-Metallkomplexen der Typen ML2(SO2)2, ML2(SO2) und ML3(SO2) (M = Ni(0), Pd(0); L = t-Phosphan) werden beschrieben. In Abhängigkeit der Phosphan-Coliganden entstehen Nickel(0)-SO2-Komplexe mit η1-planar, η1-pyramidal und η2-S.O (side on) koordiniertem SO2. Dagegen dominiert im Falle der bislang dargestellten Palladium(0)-SO2-Komplexe die η1-pyramidale Koordinationsgeometrie.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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