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Analysis of haemoperfusion columns for evaluation of treatment of phenobarbital overdosage (1980)

Wolff, Frederik A. ; Smit, Nicole D.

Springer

Archives of toxicology 43 (1980), S. 233-235

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ISSN: 1432-0738

Keywords: Haemoperfusion ; Drug extraction ; Phenobarbital ; Drug overdose

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract A simple procedure for the extraction of phenobarbital from charcoal haemoperfusion columns is presented. This method enables to evaluate the efficacy of treatment of poisoned patients with haemoperfusion. The applicability of this procedure is tested with four columns which were used in the treatment of two patients with severe phenobarbital intoxication. When an appropriate internal standard and solvent are used, this method is applicable for any drug.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00297589

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