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  • 1
    Electronic Resource
    Electronic Resource
    Identification of Somatosensory Pathways by Focal-Cooling-Induced Changes of Somatosensory Evoked Potentials and EEG-Activity – an Experimental Study (1999)
    Springer
    Acta neurochirurgica 141 (1999), S. 647-654 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: Eloquent cerebral areas; intraoperative identification; cortical cooling; intraoperative monitoring; somatosensory evoked potentials; electroencephalography.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  Object. Function-preserving neurosurgery requires methods to identify functionally important CNS-areas intraoperatively. We investigated whether a combination of focal cerebro-cortical cooling and monitoring of somatosensory evoked potentials (SEP) is suited for this task, i.e. whether it is able to outline structures belonging to the somatosensory pathway.  Methods. In 17 Wistar rats the somatosensory cortex was focally cooled by 20°C below the initial tissue temperature for periods of five minutes. A cryoprobe with a tip diameter of 3 mm was used and tissue temperatures were measured below and at different distances to the cryoprobe. Tibial nerve evoked SEPs and EEG-spectra were recorded continuously.  Results. During cortical cooling the SEP-responses showed a marked delay and amplitude increase of the cortically generated components P13 and N18 and a small latency increase of the subcortically generated wave III. EEG-spectra were depressed mainly in the low frequency range. All cooling effects were reversible and in light- as well as electron-microscopic examinations no tissue damage was found.  Conclusions. Focal cooling of the cortex induces easily recognizable and reversible changes of the bio-electrical activity without causing any histological damage. Therefore the method seems suitable for identifying eloquent areas. It can be expected that clinical application of the cooling technique in combination with intraoperative electrophysiological monitoring will be helpful to further lower the risk of neurosurgical operations.  We propose that cooling mainly interferes with the synaptic transmission within the somatosensory cortex, because the observed amplitude increase can be explained by cold-induced depression of inhibitory cortical activity (disinhibition).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010050355
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  • 2
    Electronic Resource
    Electronic Resource
    Acute hydrocephalus as a late complication of hemispherectomy (1994)
    Springer
    Acta neurochirurgica 131 (1994), S. 253-259 
    Details
    ISSN: 0942-0940
    Keywords: Hemispherectomy ; hydrocephalus ; ICP recordings
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two cases of acute hydrocephalus 34 and 27 years after hemispherectomy are presented. Both were examined by intracranial pressure recordings and treated with shunting procedures. The recordings gave evidence of raised baseline values of intracranial pressure and showed pathological B-wave activity in over 80% of the recording time. The problem of free communication between the different compartments after hemispherectomy and different surgical approaches to solve the problem are discussed. Open surgery is not advocated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01808623
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Posterpräsentationen 54 (1983)
    Springer
    Archives of gynecology and obstetrics 235 (1983), S. 477-477 
    Details
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02428767
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    Paper (German National Licenses)
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