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  • 1
    Electronic Resource
    Electronic Resource
    Kinetics of the Condensation of Anilines with Formaldehyde (1951)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 73 (1951), S. 1715-1717 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01148a085
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  • 2
    Electronic Resource
    Electronic Resource
    A novel missense mutation in exon 4 of the human coproporphyrinogen oxidase gene in two patients with hereditary coproporphyria (1997)
    Springer
    Human genetics 〈Berlin〉 99 (1997), S. 199-201 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Hereditary coproporphyria (HCP) is an autosomal dominant disease characterized by a deficiency of coproporphyrinogen oxidase. To date, four mutations of the gene have been reported. We report here another mutation in two Japanese families with HCP, which was revealed by analysis of polymerase chain reaction (PCR)-amplified DNA fragments of the gene by a direct-sequencing method. A point mutation, G to A, was found in exon 4 of the gene at position 538 of the cDNA from the reported putative translation initiation codon ATG. This mutation results in a glycine to arginine substitution at amino acid 180. Two carriers in the family were successfully diagnosed by detecting the mutation using restriction analysis of the PCR products.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004390050338
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  • 3
    Electronic Resource
    Electronic Resource
    Shading during the Early Grain Filling Period Does Not Affect Potential Grain Dry Matter Increase in Rice (2000)
    Springer
    Semigroup forum 92 (2000), S. 411-417 
    Details
    ISSN: 1432-2137
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: 10 ) has been believed to reduce potentiality of grain dry matter increase (GP) and decrease the final grain weight (GF). However, we suspect that assimilate shortage during DAY10 does not determine GF, if assimilate supply during the rest of the grain filling period (GPERIOD) meets subsequent requirements for realizing GP. Our objective was to determine if GP is in fact affected by shortage of assimilate supply caused by shading during DAY10. Plots of rice (Oryza sativa L.) grown under paddy field conditions were subjected to three strengths of shading for DAY10. After the shades were removed, the plots were divided into two groups. Plants in the first group were thinned to half the plant population density, while the second group was left at normal spacing. GF in the unthinned group was reduced depending on the strength of the shade, but weights in the thinned group almost reached those of nonshaded control plants, except in the most heavily shaded plots, where weights were slightly reduced. In pot experiments simulating crop stand, GF all reached those of control plants when the pots were exposed to abundant radiation after being subjected to heavy shading during either the early or mid-GPERIOD. These results suggest that rice plants are capable of recovering from early reduction in grain growth rate at least until the mid-GPERIOD, and shortage of available assimilate during DAY10 does not determine GP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/
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  • 4
    Electronic Resource
    Electronic Resource
    Capability of complement fixation of pemphigus antibodies in vitro (1977)
    Springer
    Archives of dermatological research 260 (1977), S. 1-6 
    Details
    ISSN: 1432-069X
    Keywords: Complement fixation ; Pemphigus antibodies ; Complement immunofluorescent staining ; Bullous diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mit Hilfe von dem kombinierten in vitro-Immunofluores-cenzkomplementfixationstest wurde in vitro-Bindung von Komplement durch Pemphigusantikörper untersucht. Drei Seren aus den 25 Seren von 22 Patienten mit Pemphigus zeigten positive Bindung von Komplement (K3), während die übrigen Seren negative Befunde zeigten. Die Spezifitätskontrolltests bestätigten, daß die positive Reaktionen spezifisch für Komplementfixation waren. Diese Komplementbindungsantikörper zeigten einen niedrigeren Titer als die korrespondierenden IgG-Antikörper und konnten nur im ausgedehnten Krankheitszustand gefunden werden. Diese Ergebnisse belegten, daß Pemphigusantikörper das Komplement in vitro fixieren. Jedoch gibt es Diskrepanzen zwischen in vivo-Komplementsvorkommen und in vitro-Komplementsbindung. Die genaue Rolle des Komplements bei der Pemphigusacantholyse muß noch weiter untersucht werden.
    Notes: Summary The capability of complement fixation of pemphigus antibodies was tested using combined in vitro complement immunofluorescent (IF) staining methods. Three sera out of 25 serum samples from 22 pemphigus patients revealed positive reactions, while all other sera gave negative results. Specificity control tests confirmed the positive reactions to be specific for complement staining. Complement fixing pemphigus antibodies were titrated lower than corresponding IgG antibodies and were demonstrable only in the extensive stage of the disease. Thus, the present work supplied evidence that pemphigus antibodies fix complement in vitro. However, the discrepancy still remains between the in vivo deposition of complement in most cases of pemphigus and in vitro capability of complement fixation in only few cases. More investigations should be needed to explain the exact role of complement in pemphigus acantholysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00558008
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  • 5
    Electronic Resource
    Electronic Resource
    Reply to the letter to the editor by Kumar, Beutner, Chorzelski, and Jablonska (1979)
    Springer
    Archives of dermatological research 264 (1979), S. 261-262 
    Details
    ISSN: 1432-069X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00431139
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    Paper (German National Licenses)
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