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  • 1
    Electronic Resource
    Electronic Resource
    Increased histidine decarboxylase (HDC) activity in human colorectal cancer: Results of a study on ten patients (1988)
    Springer
    Inflammation research 23 (1988), S. 357-360 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Following numerous reports of high histidine decarboxylase (HDC) activity in tumour-bearing animals, the present work was designed to determine the activity of this enzyme in normal and tumour tissues in a series of ten surgical patients with colorectal carcinoma. Significantly increased HDC activity, almost double that of normal tissues, was found in specimens from extirpated human tumours. These results, obtained under reliable sampling and measurement conditions indicated that changes in the enzymic activity of HDC may have a significant role in the development of colorectal tumour cells. Inhibition of the enzyme activity in human cancer subjects may retard or impede tumour growth and perhaps limit the spread of metastases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02142587
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Changes in histamine synthesis, tissue content and catabolism in human breast cancer (1989)
    Springer
    Inflammation research 27 (1989), S. 227-231 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The present study in 10 breast cancer patients supports the concept that newly synthetized, nascent histamine is involved in tumour growth. Histidine decarboxylase (HDC) activity is increased in mammary tumour tissue compared to healthy mammary gland-, skin- and muscle tissue in all but one patient studied. The newly formed histamine is probably not stored in the tumor tissue. Significantly decreased histamine concentrations were measured in parallel samples in the tumour tissue. Moreover, the preliminary results from urinary analysis of histamine and Nτ-methylhistamine in 3 of the 10 patients studied showed a significant decline after tumour extirpation compared to preoperative values.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02222247
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Laparoscopic ileal-loop conduit (1994)
    Springer
    Surgical endoscopy and other interventional techniques 8 (1994), S. 114-115 
    Details
    ISSN: 1432-2218
    Keywords: Laparoscopy ; Bladder cancer ; Bricker operation ; Ileal conduit ; Minimally invasive surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe our experience with a laparoscopic ileal-loop conduit technique for an elderly high-risk patient with bladder cancer. Four ports were used. The ileal segment was sectioned and isolated, ileal continuity was restored, and the ureter was implanted into the ileal segment conduit, extracorporeally. Conduit stoma was formed in one port. Operating time: 4 h. Recovery uneventful. The patient was discharged on the sixth postoperative day and is symptom-free at present and under radiotherapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00316621
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    New endoscopic surgery instrument: separator combined with sound for lavage and aspiration (1992)
    Springer
    Surgical endoscopy and other interventional techniques 6 (1992), S. 80-81 
    Details
    ISSN: 1432-2218
    Keywords: Laparoscopic surgery ; Surgical laparoscopic instruments
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Designed to make laparoscopy easier, this simple, multi-use instrument combines a separator with a sound for lavage and aspiration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02281087
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  • 5
    Electronic Resource
    Electronic Resource
    Common bile duct stones after laparoscopic cholecystectomy and its treatment (1994)
    Springer
    Surgical endoscopy and other interventional techniques 8 (1994), S. 1182-1185 
    Details
    ISSN: 1432-2218
    Keywords: Laparoscopic cholecystectomy ; Common bile duct stones ; Intravenous cholangiography ; Intraoperative cholangiography ; ERCP ; Transparietohepatic cholangiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In the present work we recount our experience in handling common bile duct stones (CBDS) in our first 100 cases of laparoscopic cholecystectomy. In the first 50 cases our diagnostic procedures involved the use of ultrasound exploration and intravenous cholangiotomography 48 h before laparoscopic surgery. We found three cases of residual CBDS. One of the cases was treated by means of ERCP. The other two cases were resolved by carrying out a transparietohepatic cholangiography after the ERCP procedure failed. After this experience, we changed our strategy, introducing the intraoperative cholangiography in the cases with an unclear diagnosis. With this new approach, no residual CBDS occurred in the following 50 cases. These findings demonstrate the following: (1) In our hands, intravenous cholangiography is not more effective than ultrasound exploration in resolving dubious cases. (2) These dubious cases are more effectively diagnosed by means of selective intraoperative cholangiography. (3) When CBDS is treated by transparietohepatic cholangiography it proves to be less uncomfortable for the patient than ERCP and, as we found, even more efficient in removing the stones, although our experience is based on only two cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00591046
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  • 6
    Electronic Resource
    Electronic Resource
    The evolution of postoperative ileus after laparoscopic cholecystectomy (1993)
    Springer
    Surgical endoscopy and other interventional techniques 7 (1993), S. 416-419 
    Details
    ISSN: 1432-2218
    Keywords: Postoperative ileus ; Laparoscopic cholecystectomy ; Sympathetic blockade
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Our study is prompted by the arrival of laparoscopic cholecystectomy in connection with the evolution of postoperative ileus (PI) and by its avoidance of the intraabdominal handling implied in conventional cholecystectomy. With this aim a prospective, controlled, randomized, and blind clinical trial was designed using 100 patients divided into five groups (n=20): I, conventional cholecystectomy (CC); II, CC + injection of 20 ml bupivacaine 0.5% into the mesentery root; III, CC + 7.5 mg propanolol i.v. and 0.5 mg neostigmine s.c., postoperatively until the first defecation; IV, II + III; and V, laparoscopic cholecystectomy. The shortest period of PI was observed in group V. This period increases notably in group IV (53 h), group II (72 h), and group III (84 h) relative to the control group with (89 h). This reduction in PI time runs parallel with an improvement in the patient's general state of well-being. We concluded that after laparoscopic cholecystectomy PI is nonexistent. Furthermore, this study confirms the correlation between the avoidance of intraabdominal manipulation and the evolution of postoperative ileus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00311733
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  • 7
    Electronic Resource
    Electronic Resource
    Erhöhung der Gallensäureabsorption nach totaler Dünndarmresektion bei der Ratte (1984)
    Springer
    Langenbeck's archives of surgery 363 (1984), S. 79-82 
    Details
    ISSN: 1435-2451
    Keywords: Bile salts ; Absorptive capacity ; Intestinal resection ; Increase of absorptive capacity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Gallensalze setzen den enterohepatischen Kreislauf fort. Die Cholsäure (Carboxylic14C), nach ihrer intravenösen Injektion verteilt sich im Niveau des Portalkreislaufes, Dünndarmwand, Inhalt des Dünndarms, Leber und Stuhl, welches als gutes Zeichen der Absorbierungskapazität der Epithelzellen des Darms betrachtet werden kann. In Ratten, bei denen eine totale Dünndarmresektion (60–80 cm) durchgeführt wurde, beobachtete man nach 7 Tagen eine bedeutende Verminderung der Absorbierung der Cholsäure. Trotzdem ist 30 Tage nach der Operation das Gewicht der Tiere sowie die radioaktiven Befunde gleich den Tieren der Kontrollgruppe, und zwar im Blut der Portalvene und der V. Cava, sowie im Darminhalt, Leber und Stuhl. In dieser Studie wurde eine Erhöhung der Absorbierungskapazität der Epithelzellen des Dünndarms beobachtet.
    Notes: Summary Bile salts undergo an enterohepatic circulation. The relative distribution of labelled cholic acid in portal blood, enterocytes, intestinal contents and feces, following intravenous injection of (carboxylic-14C) cholic acid, can be considered as an indication of the absorptive capacity of the epithelium cells. Seven days after a massive small intestinal resection (60–80 cm), the animal weight and the bile salt absorption were significantly decreased. Nevertheless, thirty days after the operation, weight and radioactivities reached the values found in the controls: in portal and cava blood, liver, intestinal contents and feces. An increase of the absorptive capacity of the intestinal epithelial cells was also observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01261056
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