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  • 1
    Electronic Resource
    Electronic Resource
    Allergic contact dermatitis from pentylene glycol in an emollient cream, with possible co-sensitization to resveratrol (2003)
    Oxford, UK : Munksgaard International Publishers
    Contact dermatitis 48 (2003), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0536.2003.00073.x
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  • 2
    Electronic Resource
    Electronic Resource
    Somaclonal variation versus chemically induced mutagenesis in tomato (Lycopersicon esculentum L.) (1987)
    Springer
    Theoretical and applied genetics 74 (1987), S. 733-738 
    Details
    ISSN: 1432-2242
    Keywords: Tomato ; Somaclonal variation ; Chemical mutagenesis ; Mutants
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A comparison was made of the type and frequency of mutational events found in the progeny of tomato plants regenerated after one passage in vitro with those induced by chemical mutagenesis with ethyl methane sulphonate. Several mutants were recovered in the progeny of regenerated and mutagenized plants of two cultivars of tomato. They can be grouped into the following categories: seedling lethality, male sterility, resistance to Verticillium, short stature, change in number of lateral shoots or in leaf shape. The results indicate that the two sources of variability differ in their effect, changing the spectrum and frequency of the mutants as well as, at least in some cases, their pattern of segregation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00247550
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  • 3
    Electronic Resource
    Electronic Resource
    Autopsy rate in younger and older hospitalized patients (1986)
    Springer
    European journal of epidemiology 2 (1986), S. 151-157 
    Details
    ISSN: 1573-7284
    Keywords: Autopsy ; Clinico pathological correlations ; Elderly
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A retrospective study of the autopsy rate of the clinico-pathological correlations was made in a group of inpatients. The trend of autopsy rate was observed in all impatients died in a university hospital during a nine year period (from 1975 to 1983). The agreement between the clinical and pathological death diagnosis was retrospectively controlled in 294 consecutive patients died and submitted to autopsy in the same hospital during a 6 month period (from January to June 1983). The results show that: 1) In the oldest (〉 60 yrs) patients, the autopsy rate trend was significantly reduced from 1975 to 1983, whereas the hospital admissions and the mortality rate increased. 2) In the youngest subjects (〈 60 yrs), the autopsy rate trend, the hospital admissions and the mortality rate did not significantly change from 1975 to 1983. 3) In all the years considered, the autopsy rate was significantly reduced in the oldest class (p 〉 0.01). 4) The agreement between the clinical and pathological diagnosis was observed in 83% of cases in the 〈 60 years class and in 63°% of cases in the 〉 60 yrs class (p 〉 0.001). 5) The association of main disease with other diseases was significantly more frequent in the 〉 60 yrs class with respect to the 〈 60 yrs class (p 〈 0.01). It has been concluded that the autopsy, expecially in the elderly, is absolutely necessary for a better quality control of the clinical diagnosis and of the medical care.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00157027
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  • 4
    Electronic Resource
    Electronic Resource
    B12-unresponsive methylmalonic aciduria in a female infant (1980)
    Springer
    Journal of inherited metabolic disease 3 (1980), S. 91-92 
    Details
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02312536
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  • 5
    Electronic Resource
    Electronic Resource
    Recurrent comatose state with red urine in a female infant (1982)
    Springer
    Journal of inherited metabolic disease 5 (1982), S. 21-22 
    Details
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01799809
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  • 6
    Electronic Resource
    Electronic Resource
    A case of pseudovitamin D deficiency-like rickets in an infant treated with 1,25-dihydroxycholecalciferol. Preliminary note (1978)
    Springer
    Journal of inherited metabolic disease 1 (1978), S. 183-185 
    Details
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01805593
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  • 7
    Electronic Resource
    Electronic Resource
    Accurate lymph-node detection in colorectal specimens resected for cancer is of prognostic significance (1999)
    Springer
    Diseases of the colon & rectum 42 (1999), S. 143-154 
    Details
    ISSN: 1530-0358
    Keywords: Colorectal cancer ; Lymph node ; Pathology ; Prognosis ; Local recurrence ; Metastasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: Lymph-node involvement is the most important prognostic factor in colorectal cancers. Many staging systems adopted node status as a parameter of tumor classification. However, the number of identified and positive glands varies across articles, depending on specimen examination. There is a consistent risk of substaging tumors and undertreating patients. Aim of this study was to investigate the prognostic significance of different pathologic methods. METHODS: Eight hundred one patients who underwent curative resection of colorectal cancer entered the study and were divided into two groups. In Group 1 the specimen was “en bloc” fixed, and nodes were identified by sight and palpation. In Group 2 the mesentery of the excised specimen was dissected away from the bowel, stretched, and pinned to cork board. The mesenteric segment surrounding the origin of principal vessels was divided from the segment surrounding the colic vessels. All specimen segments were fixed, node identification being performed by sight and palpation. Examined and positive nodes were recorded, and metastatic rate and incidence was calculated in the two groups. Patients were classified with used of different staging systems. Survival rates were calculated, related to tumor stage, and compared statistically. Pathologic procedures were included in a multivariate analysis. RESULTS: A significantly higher number of detected and positive nodes and metastatic rate (37.5vs. 30.2 percent;P〈0.05) were observed in Group 2; 45.2 percent of Group 2 and 25.3 percent of Group 1 cases had more than three positive nodes (P〈0.05). In Group 2 several patients shifted from earlier to more advanced stages compared with Group 1 cases. Five-year and ten-year survival rates were significantly higher (P=p.pr) in Group 2 (81.5 and 77.2 percent) than in Group 1 (76.7 and 61.5 percent), mostly in patients with TNM Stage N0. Survival analysis related to Astler and Coller's and Tang's classifications confinrmed such features. Higher rates of local recurrences and distant metastases were found in Group 1, particularly if related to node status (P〈0.05). Multivariate analysis demonstrated the pathologic method is an independent prognostic factor. CONCLUSIONS: This study demonstrates the prognostic impact of specimen examination. Inaccurate methods could downstage the tumor and exclude the patient from adjuvant therapies, with detrimental effects on the outcome of the case.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02237119
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  • 8
    Electronic Resource
    Electronic Resource
    Ethical issues concerning potential global climate change on food production (1992)
    Springer
    Journal of agricultural and environmental ethics 5 (1992), S. 113-146 
    Details
    ISSN: 1573-322X
    Keywords: climate change ; food ; agriculture ; ethics ; technologies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Philosophy
    Notes: Abstract Burning fossil fuel in the North American continent contributes more to the CO2 global warming problem than in any other continent. The resulting climate changes are expected to alter food production. The overall changes in temperature, moisture, carbon dioxide, insect pests, plant pathogens, and weeds associated with global warming are projected to reduce food production in North America. However, in Africa, the projected slight rise in rainfall is encouraging, especially since Africa already suffers from severe shortages of rainfall. For all regions, a reduction in fossil fuel burning is vital. Adoption of sound ecological resource management, especially soil and water conservation and the prevention of deforestation, is important. Together, these steps will benefit agriculture, the environment, farmers, and society as a whole.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01966356
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  • 9
    Electronic Resource
    Electronic Resource
    Paraneoplastic syndrome in the course of Hodgkin disease. Case report (1989)
    Springer
    Neurological sciences 10 (1989), S. 207-210 
    Details
    ISSN: 1590-3478
    Keywords: Hodgkin disease ; paraneoplastic syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Viene descritto il caso di una paziente affetta da Morbo di Hodgkin, colpita da sindrome paraneoplastica di inusuale estensione, con interessamento sia del SNC che del SNP. Con la gravità del quadro clinico contrasta la modestia delle alterazioni neuropatologiche osservate. Vengono brevemente discussi i problemi eziologici e clinici delle sindromi paraneoplastiche interessanti il SN.
    Notes: Abstract A woman with Hodgkin disease presented a neoplastic syndrome of unusual magnitude affecting both the CNS and PNS. The severity of the clinical pattern contrasted strongly with the paucity of neuropathological findings. The report is followed by a brief discussion of the etiological and clinical problems of paraneoplastic syndromes affecting the nervous system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02333621
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