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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 145 (2001), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background The blocking action of botulinum toxin type A (BTX-A) on cholinergically innervated sweat glands has been used successfully to treat patients with focal hyperhidrosis. Objectives To investigate the long-term efficacy and safety of intradermal injections of BTX-A. Methods We performed an open-label study in 61 patients treated over a period of 3 years for axillary or palmar hyperhidrosis. A total dose of 400 mU BTX-A (Dysport®) was injected into both axillae or 460 mU BTX-A (Dysport®) into both palms. The injections were repeated after relapse. Objective quantification of sweat production was performed using digitized ninhydrin-stained sheets. Results Four weeks after BTX-A treatment the median reduction in sweat production was 71% compared with baseline (P 〈 0·001) in the axillary group and 42% (P = 0·005) in the palmar group. Subjective assessment of sweat production by the patients using a visual analogue scale (0, no sweating; 100, the most severe sweating) showed a significant reduction in both the axillary (P 〈 0·001) and palmar groups (P 〈 0·001). Secondary disturbances due to focal hyperhidrosis interfering with daily activities were markedly improved in both groups. The median time interval between the sets of injections was 34 weeks for axillary hyperhidrosis and 25 weeks for palmar hyperhidrosis. The treatment of palmar hyperhidrosis was complicated by transient but not disabling weakness of the small hand muscles in nine of 21 patients. Conclusions Repeated intradermal injections of BTX-A in patients with axillary and palmar hyperhidrosis are as effective as first treatments.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 145 (2001), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Barthel-Index ; Aktivitäten des täglichen Lebens ; Verhalten ; Kognition ; Mentale Funktion ; Keywords Activities of daily living ; ADL ; Barthel index ; Behaviour ; Cognitive functions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The Barthel Index (BI) is the most commonly used scale for assessing impairment of activities of daily living (ADL). For a global view of patients' abilities and the care needed in everyday neurorehabilitation practice, additional information about basic psychological and cognitive functions is essential. We therefore designed a new disability scale comprised of assessments of consciousness, approachability, orientation, memory, behaviour, emotions, communication, problem solving, perception, and behaviour at night. The scale shows exactly the same inner structure as the BI, with ten items and a score of up to 20 in steps from 0–100% (or 0–20 points). By a careful weighing of the items, the final score of the neuromental index (NMI) should create a clearer picture of both the disabilities and the needed resources. A second aim was to cover a broad range of patients including those in coma and coma remission states and those with only slight neuropsychological or behavioural symptoms. The NMI was examined with a group of 179 neurorehabilitation inpatients and proved to be highly valid, reliable, and practicable. It was designed to enable a global assessment of disability as well as the care resources needed, even in patients with different disability levels in ADL and psychological and cognitive functions.
    Notes: Zusammenfassung Der Barthel-Index (BI) ist die am weitesten verbreitete Beurteilungsskala für die Aktivitäten des täglichen Lebens. Für die Einschätzung von Fähigkeiten und Betreuungsaufwand im Alltag der Neurorehabilitation sind aber auch Störungen der psychischen und mentalen Grundfunktionen, die durch den BI nicht erfasst werden, von wesentlicher Bedeutung. Wir haben eine Skala erstellt, die Fähigkeitsstörungen in den Bereichen Bewusstsein, Kontaktfähigkeit, Orientierung, Verhalten, Emotion, Kommunikation, Gedächtnis, Problemlösung, Wahrnehmung und Nachtruhe einschließt und die in einer 0–100% Skalierung bzw. der Vergabe von 0–20 Punkten für die 10 Items die exakt gleiche Struktur wie der BI aufweist. Es wurde in der Erstellung der Items darauf Wert gelegt, dass der Summenscore die Fähigkeitsstörungen und den Betreuungsaufwand von komatösen bzw. Komaremissionspatienten (am unteren Skalenende) und Patienten mit geringen Vehaltens- oder neuropsychologischen Störungen (am oberen Skalenende) möglichst wirklichkeitsnahe abbildet. Der Neuromentalindex wurde an 179 Neurorehabilitationspatienten bezüglich seiner Testgütekriterien untersucht und erwies sich als in hohem Maß valide, reliabel und praktikabel.
    Type of Medium: Electronic Resource
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