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  • 1
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A continuing theme of our laboraory, has been the understanding of human DNA polymerases at the structural level. We have purified DNA polymerases delta, epsilon and alpha from human placenta. Monoclonal antibodies to these polymerases were isolated and used as tools to study their immunochemical relationships. These studies have shown that while DNA polymerases delta, epsilon and alpha are discrete protiens, they must share common structural features by virtue of the ability of several of our monoclonal antibodies to exhibit cross-reactivity. A second approach we have taken is the molecular cloning of human DNA polymerase delta and epsilon. We have cloned the DNA polymerase delta cDNA, and this has allowed us to compare its primary structure to those of human polymerase alpha and other members of this polymerase family. Multiple sequence alignments have revealed that human DNA polymerase delta is also closely related to the herpes virus family of DNA polymerases. In situ hybridization has shown that the human DNA polymerase delta gene is localized to chromosome 19 q13.3–q13.4. In order to further determine the functional regions of the DNA polymerase δ structure we are currently expressing human pol δ inE. coli and baculovirus systems. Other work in our laboratory is directed toward examining the expression of DNA polymerase δ during the cell cycle.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A new method to improve the morphology and the microstructure of sputtered bismuth-substituted garnet films for optical storage is discussed. The method employs a high ramp up rate and recurrent annealing as well as quenching in an air environment, which results in smaller grain size, smoother surface, and less void volume in the garnet films than that from a conventional oven annealing. We have discovered that samples prepared with a more recurrent annealing only appeared as a single garnet phase, and the samples with a less recurrent annealing appeared as a garnet phase as well as DyFeO3 phase. We observed the microstructure of the annealed films with scanning electron microscopy (SEM). By applying the new method, the as-deposited films had been successfully crystallized to the (BiDy)3(FeGa)5O12 garnet phase with the grain size of about 300–400 A(ring). They exhibited excellent magneto-optical properties with a high coercive force about 1300 Oe and an effective Kerr angle of 1.5°. The crystallization process of as-deposited amorphous films as well as the structure, composition, and magnetic and magneto-optical properties of the crystallized garnet films were examined.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 57 (1985), S. 4046-4048 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Effects of helium ion double implantation on contiguous disk (CD) bubble devices have been examined by x-ray diffraction, FMR, and annealing techniques. The results were compared with static and dynamic performance of CD devices. Samples had a composition of Sm0.29Lu0.40Y1.42Ca0.89Fe 4.11Ge0.89O12 with stripe width 3 μm, Hc=143 Oe and were implanted with 190-keV helium at 4.5×1015 He+/cm2 and 100-keV helium at 3 ×1015 He+/cm2. X-ray diffraction curves show that He ion double implantation gives a more uniform strain profile with a main strain of 0.84% and a strain induced anisotropy field of 3100 Oe. FMR spectrum results show an implantation induced anisotropy field of 3185 Oe which is in good agreement with x-ray diffraction result. The main strain decreases linearly with the annealing temperature Ta extrapolating to zero at l000 °C. The implantation induced anisotropy field also decreases with Ta, but exhibits an excess of 600 Oe over the strain anisotropy field. This excess is attributed to the suppression of growth induced anisotropy by He ion implantation. The measurements of the bubble collapse field and propagation margin on a CD track with 12-μm period at 100 kHz show that annealing at temperatures higher than 300 °C causes the performance of CD devices to degrade very rapidly. The margin becomes narrow and the minimum drive field increases. Annealing above 500 °C will kill the device.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Chinese Astronomy and Astrophysics 7 (1983), S. 241-244 
    ISSN: 0275-1062
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 235 (1996), S. 1-7 
    ISSN: 1572-946X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract An alternative approach is proposed for the study of the non-cosmological redshifts. The approach is based on the radiation formulation of the tidal gravitation acceleration in geometrodynamics and the spacetime curvature around the massive objects. The resulting formalism can be used to study the object mass and the gravitation magnitude from the observed spectral lines with redshifts.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Advanced performance materials 2 (1995), S. 231-247 
    ISSN: 1572-8765
    Keywords: crack growth ; fatigue ; fracture mechanics ; life prediction ; weight functions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The paper presents a brief review of some of the major research activities on fatigue and fracture mechanics in recent years at the Beijing Institute of Aeronautical Materials. Attention is mainly given to the studies on weight function methods for analyses of two- and three-dimensional crack problems, fatigue crack growth under variable amplitude loading, small crack effects and a fracture-mechanics-based total fatigue life prediction method.
    Type of Medium: Electronic Resource
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