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  • Articles: DFG German National Licenses  (15)
  • 1995-1999  (15)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Der Radiologe 38 (1998), S. 15-22 
    ISSN: 1432-2102
    Keywords: Key words Crohn's disease • Ultrasound • Small bowel enema • Computed tomography ; Schlüsselwörter Morbus Crohn • Ultraschall • Enteroklysma • Irrigoskopie • Computertomographie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die vorliegende Übersichtsarbeit soll die Rolle bildgebender radiologischer Modalitäten bei der interdisziplinären Betreuung von Patienten mit Morbus Crohn (MC) diskutieren. Es wird ein Konzept vorgestellt, welches die unterschiedlichen Anforderungen an die bildgebende Diagnostik im Rahmen der Erstdiagnose, der Verlaufskontrolle sowie bei der Erfassung von Komplikationen eines MC definiert. Davon ausgehend wird versucht, für die einzelnen Fragestellungen die jeweils effektivste radiologische Abklärung vorzuschlagen. Mehrere Tabellen ermöglichen einen raschen und komprimierten Überblick der diagnostischen Problemstellungen im Rahmen einer schrittweisen Abklärung der Erkrankung. Im Rahmen der Erstdiagnostik soll die radiologische Dünndarmdarstellung bei der Differentialdiagnose (MC vs. Colitis ulcerosa) hilfreich sein und das genaue Ausmaß des Dünndarmbefalles eruieren. Im Rahmen der klinischen Verlaufskontrolle ist die Darmsonographie ideal zur Überwachung der Erkrankung sowie zur frühen Erfassung von Komplikationen geeignet. Bei geringstem Verdacht auf eine Komplikation sollte sofort eine CT durchgeführt werden.
    Notes: Purpose: This paper discusses the role of different imaging modalities in the diagnostic work-up of Crohn's disease (CD). Methods: We present a concept, which emphasizes different diagnostic aspects with regard to primary diagnosis, follow-up and assessment of complications of CD. The most effective imaging approach to various diagnostic problems of CD is discussed in detail. Discussion: With regard to the primary diagnosis barium studies should contribute to differentiate between CD and ulcerative colitis. Beyond that, these studies should evaluate location and extent of disease. During the follow-up bowel sonography provides staging of disease and enables the detection of complications at an early stage. CT is a valuable tool in the preoperative assessment of complications, such as fistulae and abscesses.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2102
    Keywords: Key words Laryngeal carcinoma • Laryngectomy • Complication • Videofluoroscopy • Pharynx • Aspiration ; Schlüsselwörter Larynxkarzinom • Laryngektomie • Komplikation • Videocinematographie • Pharynx • Aspiration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Durch die Verbesserung der larynxchirurgischen Techniken sowie auch die Entwicklung der adjuvanten Radiochemotherapie ist es meistens möglich, Larynxkarzinompatienten funktionserhaltenden Larynxteilresektionen zuzuführen und früher als inoperabel betrachtete Tumore durch eine totale Laryngektomie kurativ zu resezieren. Radiologische Untersuchungen, insbesondere Pharyngographie und Videocinematographie, sind die wichtigsten Methoden, um postoperative Komplikationen nachzuweisen. In der vorliegenden Übersicht wird die videocinematographische Untersuchungstechnik bei Verdacht auf postoperative Komplikation nach Larynxresektion erklärt. Weiterhin wird das typische radiologische Erscheinungsbild der Früh- und Spätkomplikationen, wie Fisteln, Hämatome, Aspiration, Strikturen, Hypertrophie des pharyngoösophagealen Sphinkters, Tumorrezidive und metachrone Zweittumore gezeigt. Die Videocinematographie ist die sensitivste Untersuchungsmethode, um gleichzeitig funktionelle Störungen des Schluckaktes und strukturelle Veränderungen nach Larynxresektionen nachweisen zu können.
    Notes: Summary In past decades, the surgical techniques for treating laryngeal carcinoma have been vastly improved. For circumscribed tumors, voice-conserving resections are possible and for extensive neoplasms, radical laryngectomy, sometimes combined with chemoradiation, has been developed. Postoperative complications regarding swallowing function are not uncommon. Radiologic examinations, especially pharyngography and videofluoroscopy, are most often used to evaluate patients with complications after laryngeal surgery. An optimized videofluoroscopic technique for evaluation of complications is described. The radiologic appearance of early and late complications, such as fistulas, hematomas, aspiration, strictures, dysfunction of the pharyngoesophageal sphincter, tumor recurrence, and metachronous tumors is demonstrated.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Der Radiologe 37 (1997), S. 197-204 
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Lebertransplantation ; Komplikation ; Radiologische Diagnostik ; Key words Liver transplantation ; Complications ; Radiological diagnosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Introduction: Orthotopic liver transplantation (OLT) has become an accepted treatment for end-stage liver disease. However, postoperative complications result in significant patient morbidity and mortality. Early detection and treatment of these complications is therefore of utmost importance. Materials and methods: We retrospectively reviewed the postoperative complications of the patients who underwent OLT at our institution. Duplex Doppler sonography and cholangiography were the primary imaging modalities in postoperative evaluation of the transplanted liver. Other important techniques were CT, MRI, and angiography, which may contribute to a reliable diagnosis of vascular or biliary complications. Results: Second to primary organ dysfunction, vascular complications are the most frequent cause of graft loss. Thrombosis of the hepatic artery is the most common and most serious vascular complication, with a reported incidence from 4 to 42 %. Bile duct sludge, leaks and strictures are frequent complications after liver transplantation, which can contribute to graft dysfunction. Biliary tract complications usually occur within the first 3 months and require interventional radiological or surgical therapy. Since liver transplant recipients undergo immunosuppressive therapy, they are at increased risk of developing late post-transplant malignancies, which are best depicted by US, CT or MRI. However, radiological diagnosis of lymphoproliferative disorder has to be confirmed by liver biopsy. Conclusion: Cholangiography and Duplex sonography are routinely used in the postoperative evaluation of patients with OLT. CT, MRI, and angiography are problem-solving tools in equivocal cases.
    Notes: Zusammenfassung Einleitung: Die orthotope Lebertransplantation hat sich zu einer etablierten Therapie bei Lebererkrankungen im Endstadium entwickelt. Der frühe Nachweis und die prompte Therapie eventueller Komplikationen sind für das Überleben des Patienten und des Organs entscheidend. Material und Methode: Es wurden im eigenen Krankengut die postoperativen Komplikationen nach OLT retrospektiv ausgewertet. Die Duplexsonographie und die Cholangiographie erwiesen sich als die primären Untersuchungsmethoden der Wahl zum Nachweis vaskulärer oder biliärer Komplikationen. CT, MRI und die Angiographie waren in Problemfällen wertvolle additive bildgebende Verfahren zur Diagnosesicherung. Ergebnisse: Nach der primären Organdysfunktion sind die vaskulären Komplikationen als häufigste Ursache für den Verlust des Spendeorgans anzuführen. Die Thrombose der A. hepatica ist die häufigste vaskuläre Komplikationen mit einer Inzidenz von 4–42 %. Galleleaks, -sludge und -strikturen sind häufige Komplikationen, die letztlich zu einer Dysfunktion des transplantierten Organs führen können. Biliäre Komplikationen treten gehäuft in den ersten 3 Monaten auf und erfordern eine interventionelle oder chirurgische Therapie. Da Patienten nach OLT einer immunsuppressiven Therapie unterliegen, sind sie einem erhöhten Risiko einen lymphoproliferativen Tumor zu entwickeln ausgesetzt. Diese Posttransplant-Tumore können mit US, CT und MRI ausgezeichnet abgegrenzt werden, erfordern jedoch eine Sicherung der Diagnose durch eine Feinnadelpunktion. Schlußfolgerung: Die postoperative Verlaufskontrolle und der Nachweis von Komplikationen nach OLT ist eine Domäne von Cholangiographie und Duplexsonographie. In Problemfällen kommen CT, MRI und Angiographie zum Einsatz.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 154 (1995), S. 640-642 
    ISSN: 1432-1076
    Keywords: Key words Recurrent suppurative ; thyroiditis ; Pyriform sinus fistula ; Childhood
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Acute suppurative thyroiditis is a rare disease, particularly in childhood. We present a case with recurrent acute suppurative thyroiditis due to a pyriform sinus fistula originating from the fourth branchial pouch. The typical symptoms of a piriform sinus fistula are recurrent left-sided pain and swelling of the neck with signs of acute bacterial inflammation. Diagnosis should be made by high resolution ultrasound, barium meal studies and endoscopic examination. During acute exacerbations treatment with antibiotics is indicated, but permanent cure can only be attained by complete fistulectomy.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 154 (1995), S. 109-111 
    ISSN: 1432-1076
    Keywords: Key words Achalasia ; Growth retardation ; Growth hormone test ; Growth hormone treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 15-year-old boy with achalasia of the oesophagus is described in whom growth retardation was the presenting and misleading symptom. Growth hormone (GH) and insulin-like growth factor-I secretion were decreased but GH therapy was unsuccessful. After pneumatic dilatation of the oesophageal sphincter catch up growth occurred.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 154 (1995), S. 640-642 
    ISSN: 1432-1076
    Keywords: Recurrent suppurative thyroiditis ; Pyriform sinus fistula ; Childhood
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Acute suppurative thyroiditis is a rare disease, particularly in childhood. We present a case with recurrent acute suppurative thyroiditis due to a pyriform sinus fistula originating from the fourth branchial pouch. The typical symptoms of a piriform sinus fistula are recurrent left-sided pain and swelling of the neck with signs of acute bacterial inflammation. Diagnosis should be made by high resolution ultrasound, barium meal studies and endoscopic examination. During acute exacerbations treatment with antibiotics is indicated, but permanent cure can only be attained by complete fistulectomy.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 156 (1997), S. 838-840 
    ISSN: 1432-1076
    Keywords: Key words: Insulin dependent diabetes mellitus ; Children ; Lispro insulin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We compared the postprandial blood glucose (BG)-levels following preprandial regular insulin or lispro insulin before and after eating in adolescents with diabetes. Lispro is a rapidly absorbed insulin analogue. Lispro insulin injected immediately before breakfast reduced the postprandial BG-rise significantly compared to the 20 min preprandially administered regular insulin (P〈0.01). Postprandial lispro injection resulted in similar BG values as the standard treatment with regular insulin 20 min preprandially. Conclusion Lispro insulin injected immediately before the meal leads to lower postprandial BG levels and seems to be an option for teenagers who use multiple preprandial insulin injections. Postprandial lispro administration could be a benefit in certain situations since it resulted in similar BG values to preprandial regular insulin.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 157 (1998), S. 802-805 
    ISSN: 1432-1076
    Keywords: Key words Insulin-dependent diabetes mellitus ; Cognitive function ; Attention ; Blood glucose level ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We compared the results of a computerized attention test (TOVA) in 38 children with insulin dependent diabetes mellitus in relation to various spontaneously occurring blood glucose levels. Testing was performed at the following blood glucose levels: 〈3.3 mmol/l (hypoglycaemia), 3.3–8.3 mmol/l (normoglycaemia) and 〉8.3 mmol/l (hyperglycaemia) . The attention (sum of errors and response time) varied significantly with the blood glucose level (P=0.002). The highest number of errors of omission and the longest response time was observed during the test run with hypoglycaemia. Age, sex, age at manifestation of the disease, metabolic control and the results of the intelligence test had no significant influence on these results. We found that attention in children with diabetes was significantly reduced compared to TOVA norms especially during mild hypoglycaemia (P〈0.001). Irrespective of the blood glucose levels, reaction time and the variability of the reaction time differed significantly between TOVA norms and diabetic children (P〈0.01). Conclusion In children with diabetes mellitus a significant reduction in attention was found at mild hypoglycaemia but as well at low normal blood glucose levels. Attention deficits due to transient lowering of blood glucose may therefore occur in diabetic children even before they are aware of hypoglycaemic symptoms.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 158 (1999), S. 362-366 
    ISSN: 1432-1076
    Keywords: Key words Type 1 diabetes ; Children ; Risk factors ; Case control ; Environmental
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this study was to investigate environmental risk factors in the development of type 1 diabetes mellitus in a population-based case-control study. Parents of all patients with manifestation of type 1 diabetes between 1989 and 1994 in Vienna were asked to complete a questionnaire (n = 114). Control children (n = 495), matched for age and sex, were randomly recruited from all schools in Vienna. Fathers of diabetic children were significantly older at the time their children were born than fathers of control children (P = 0.015). Children with diabetes were more likely to be second- or third-born children (P 〈 0.05) and fewer went to kindergarten than the control group children (P = 0.007). No significant difference in duration of gestation, percentage of delivery by caesarean section, birth weight or length was found. Neonatal jaundice was more often observed in the patient group (P = 0.038). Breast feeding was reported by 82.7% of mothers of diabetic children and by 81% of mothers of control children, and the duration of breast feeding was longer in patients than in controls (n.s.). Conclusion In our study, the development of type 1 diabetes mellitus was associated with higher paternal age and neonatal jaundice. No correlation could be found with dietary intake of cow's milk products in early infancy, vaccination and other environmental factors.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 156 (1996), S. 15-17 
    ISSN: 1432-1076
    Keywords: Key words Insulin dependent diabetes ; Austrian ; Young cohort ; Population based mortality
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract All Austrian patients with insulin dependent diabetes diagnosed between 1979 and 1990 and age at onset below 15 years were followed from manifestation until death or until 31 December 1990 by cross linking the diabetes registry data with the National Mortality database (death certificates). Out of the cohort consisting of 1185 cases, 6 had died during the study period, resulting in a standardized mortality ratio of 1.53 for the total cohort. Of the patients 50% died due to acute diabetic complications including 2 children at onset of the disease. The risk for premature death in this cohort of very young insulin dependent diabetes mellitus patients was only slightly increased. In comparison to previous studies it is rather low, but comparable to recent investigations in northern Europe. Conclusion Although the mortality of diabetic children and adolescents in Austria is only marginally higher than in nondiabetics, there are still deaths which should be preventable in this age group.
    Type of Medium: Electronic Resource
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