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  • 1
    Electronic Resource
    Electronic Resource
    Magnetic field alignability of hot-rolled anisotropic Nd-Fe-B-Cu powders : The 5th Joint MMM−Intermag Conference (1991)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 70 (1991), S. 6360-6362 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have investigated alignability of anisotropic Nd-Fe-B powders in a magnetic field when they are resin bonded by compression moulding. A high-energy anisotropic powder of Cu-added Nd-Fe-B alloys, which was fabricated by packed rolling of melt-spun ribbons, is used for the present study. The result is compared with the alignability of conventional 2:17 type Sm-Co powder. For a Nd-Fe-B-Cu powder (iHc = 16 kOe), 90% of the saturated Br value was obtained at an aligning field as low as 2 kOe, whereas for a Sm-Co powder (iHc = 12 kOe), an aligning field of 13 kOe was required to obtain the 90% value. The good alignability of the Nd-Fe-B-Cu powder is attributed to a steep rise in the initial magnetization curve. It benefits radial orientation of the powder in ring magnets, for which limitations of the aligning field exist depending upon the size of the magnet. A maximum energy product of 15 MGOe has been obtained for radially oriented Nd-Fe-B-Cu bonded magnets.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.349942
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  • 2
    Electronic Resource
    Electronic Resource
    Cu-added Nd-Fe-B anisotropic powder for permanent magnet use : 35th annual conference on magnetism and magnetic materials (1991)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 69 (1991), S. 5832-5834 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A packed-rolling method has been applied to fabricating Nd-Fe-B anisotropic powder from melt-spun ribbons; the method involves packing the ribbon materials in a steel container under a vacuum and rolling the pack at around 700 °C. The hot-rolled materials, which form a bulk in a plate-shape, exhibited a strong deformation-induced magnetic anisotropy with the easy magnetization axis parallel to the plate-thickness direction. The anisotropic powders can be obtained by pulverizing the hot-rolled materials. Hot rolling to an 82% reduction in ribbon thickness produced the following magnetic properties: iHc = 12.3 kOe, Br = 12.3 kG, and (BH)max = 36.8 MGOe for a conventional Nd14Fe80B6 alloy. We have found that additions of Cu increase the coercive force up to 19 kOe and result in a remarkable improvement in thermal stability of the anisotropic powders. The result is interpreted in terms of the suppression of grain growth by Cu additions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.347841
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  • 3
    Electronic Resource
    Electronic Resource
    A field-reversal mechanism in a reversed-field pinch (1995)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 2 (1995), S. 1182-1191 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A field-reversal mechanism in a reversed-field pinch (RFP) is studied through a three-dimensional resistive compressible magnetohydrodynamic (MHD) simulation of the single- and multiple-helicity modes. As the magnetic Reynolds number increases, the m=1 fluctuating magnetic field grows exponentially and extends radially, and then the flow begins to form the vortex structure around the core of the plasma. This radial flow acts such as to push out the toroidal magnetic field. As the dynamo electric field induced by this interaction increases near the core of the plasma, the toroidal magnetic field at the wall decreases toward the negative value and the toroidal magnetic field reverses. As a result, it is found that the field reversal is achieved by the single-helicity evolution of the m=1 mode alone, without the (m=0; n≠0) modes, and the interaction of the radial flow and the toroidal magnetic field is the most dominant source for the dynamo action on the field-reversal process. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.871396
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  • 4
    Electronic Resource
    Electronic Resource
    Status of ion sources for the Heavy Ion Medical Accelerator HIMAC : Proceedings of the 6th international conference on ion sources (1996)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 67 (1996), S. 962-964 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The Heavy Ion Medical Accelerator in Chiba (HIMAC) at National Institute of Radiological Sciences (NIRS) is the first heavy-ion accelerator complex dedicated to cancer therapy. HIMAC is equipped with two kinds of ion sources. The PIG ion source is an indirectly heated cathode type, which is operated with a very low-duty factor. The ECR ion source has a single closed ECR zone with 10 GHz microwaves. Both sources realize good stability and reproducibility with easy operation, and satisfy the requirements for radiotherapy. They have been successfully used for clinical trials since June of 1994, and several tens of cancer patients have already been treated with 290–400 MeV/u carbon beams. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1146784
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  • 5
    Electronic Resource
    Electronic Resource
    ErbB-2, a c-erbB-2-coded protein, is expressed in metastatic cells of adenocarcinoma of endometrium, cervix and ovaries (1995)
    Suite 500, 5th Floor, 238 Main Street, Cambridge Massachusetts 02142, USA : Blackwell Science Inc.
    International journal of gynecological cancer 5 (1995), S. 0 
    Details
    ISSN: 1525-1438
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Ten cases of gynecologic malignancies, including three endometrial, two ovarian and four cervical carcinomas, were studied for the expression of a 185 kDa protein (ErbB-2), coded by a proto-oncogene, c-erbB-2, in primary lesions as well as in metastatic lesions. Positive immunoreactivity was observed in all primary adenocarcinomas but not from squamous cell carcinomas. Many adenocarcinoma cells in distant metastatic sites or in tertiary lymph nodes were strongly stained for ErbB-2. These metastatic cells also showed an expression of proliferating cell nuclear antigen (PCNA). Detection of ErbB-2 mRNA by a reverse-transcription polymerase chain reaction showed that the transcription occurred exclusively in adenocarcinomas. To our knowledge, this is the first report demonstrating ErbB-2 expression in distant metastatic lesions of gynecologic cancers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1525-1438.1995.05060411.x
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  • 6
    Electronic Resource
    Electronic Resource
    New method of hot rolling for fabricating anisotropic Pr-Fe-B-based magnets (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 54 (1989), S. 1597-1598 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A unique method of hot rolling is described which fabricates high performance plate-shaped magnets from a cast Pr17Fe76.5B5Cu1.5 alloy. A flat ingot of the alloy with fine-scale columnar grains of a Pr2Fe14B phase is prepared by chill casting. The ingot is hot rolled in such a way that the roll pressure is applied perpendicular to the preferential growth direction of the columnar grains. A maximum energy product of 25.3 MG Oe has been obtained by this method.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.101391
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  • 7
    Electronic Resource
    Electronic Resource
    Effects of silicon and aluminum additions on magnetic properties of rapidly quenched Nd-Fe-B permanent magnets (1988)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 63 (1988), S. 3507-3509 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The effects of Si and Al on magnetic properties of melt-spun Nd-Fe-B base alloy permanent magnets were studied. The addition of Si to the Nd-Fe-B base alloy improves magnetic properties: it especially increases the maximum energy product (BH)max up to 20 MG Oe, remanence Br over 9 kG, and decreases intrinsic coercive force iHc. The addition of Si also increases Curie temperature and decreases reversible temperature coefficient. The combined addition of Si and Al spreads wheel surface velocity ranges to obtain (BH)max〉15 MG Oe and Br〉9 kG compared to the addition of Si only. The origin of high performance is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.341165
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  • 8
    Electronic Resource
    Electronic Resource
    Status of the HIMAC pulsed Penning source : The 8th international conference on ion sources (2000)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 71 (2000), S. 972-974 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Since 1994 at the National Institute of Radiological Sciences HIMAC, the NIRS Penning ionized-gauge ion source (PIGIS) has so far been used for radiotherapy with carbon beams and for basic research with several ion species. The source can produce beams from H2 to Fe with a charge-to-mass ratio of between 1/7 and 1/2. It is a hot-cathode type with a filament, of which the lifetime is on the order of a week and the cathode on the order of 1 month, under a low-duty pulsed operation (≤0.5%) synchronized to the ring operation. This PIGIS can produce highly charged ions: for example, 1 e mA of Ar7+ or 500 eμ A of Si5+ ions (by sputtering) under the typical arc power of 5 kW in peak. This article describes the present status of the NIRS-PIGIS. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1150362
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  • 9
    Electronic Resource
    Electronic Resource
    Serum Level of Interleukin-4 in Patients with Perennial Allergic Rhinitis During Allergen-Specific Immunotherapy (1996)
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Scandinavian journal of immunology 43 (1996), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Interleukin-4 (IL-4) may play a central role in the IgE synthesis system, the development of Th-2-like cells, and co-ordination as well as the persistence of airway inflammatory process in allergic disorders. Therefore, IL-4 plays a key role in airway allergic disorders. This study aimed at investigating the serum concentrations of IL-4 in patients with perennial allergic rhinitis, with special reference to the possible changes and the clinical relevance following long-term immunotherapy. The study has demonstrated that the serum level of IL-4 in allergic rhinitis patients before immunotherapy is significantly higher than that in non-atopic individuals. However, the serum IL-4 level in allergic rhinitis patients did not decrease following anti-allergic medications but significantly decreased following immunotherapy. The percentage decrease in IL-4 was correlated significantly with the percentage decrease in specific IgE antibodies following long-term immunotherapy. Immunotherapy also significantly decreased specific IgE antibodies, but this reduction in specific IgE antibodies was not significantly correlated with the clinical improvement. In contrast, the percentage decrease in serum IL-4 was significantly correlated with the percentage decrease in symptomatic scores. The authors interpret these data to mean that immunotherapy alters T-cell cytokine profiles in the long-term, and a decline of IL-4 following immunotherapy could modulate not only production of specific IgE antibodies but also inflammatory cellular events, leading to symptomatic relief in allergic rhinitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3083.1996.d01-269.x
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  • 10
    Electronic Resource
    Electronic Resource
    Serum Level of Soluble Interleukin-2 Receptor in Patients with Seasonal Allergic Rhinitis (1997)
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Scandinavian journal of immunology 45 (1997), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The rate of release of the soluble form of interleukin-2 receptor (soluble IL-2R) reflects T cell activation in vivo. Since T lymphocytes play a central role in respiratory allergic disorders, the measurement of serum levels of soluble IL-2R may be useful in analysing the disease state of allergic disorders. The study has aimed at investigating the seasonal changes in serum soluble IL-2R in 81 patients with seasonal allergic rhinitis due to Japanese cedar pollens, with special reference to the effect of anti-allergic pharmacotherapy and immunotherapy. Serum samples were obtained twice from each patient, before and during the pollen season, and all the serum samples were simultaneously used for determination of soluble IL-2R and cedar pollen-specific immunoglobin E (IgE). Seasonal elevation in soluble IL-2R was not associated with the good clinical outcome but was associated with the poor clinical outcome, irrespective of pharmacotherapy or immunotherapy. Additionally, successful immunotherapy suppressed seasonal elevation of serum soluble IL-2R more strongly than successful pharmacotherapy, and seasonal increase rates in soluble IL-2R were inversely correlated with the duration of immunotherapy. Seasonal increase rates in soluble IL-2R were significantly correlated with seasonal increase rates in specific IgE in both the medication group and the immunotherapy patients. These results may suggest that seasonal changes in serum soluble IL-2R may serve as an indicator for clinical outcome of seasonal allergic rhinitis, that the magnitude of T cell activation could affect specific IgE production, and that T cell activation could be gradually modulated as immunotherapy proceeds. In conclusion, seasonal changes in serum soluble IL-2R may serve as an objective indicator for clinical outcome of seasonal allergic rhinitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3083.1997.d01-392.x
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