Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Electronic Resource  (3)
Material
  • Electronic Resource  (3)
Years
  • 1
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The prevalence ofChlamydia trachomatis infection in a population of women with no symptoms of sexually transmitted disease was investigated. These women, aged 35–55 years, participated in a screening program for cervical cancer. With the use of a direct immunofluorescence method, 109 out of 2,470 smears tested were positive forChlamydia trachomatis, indicating an overall prevalence of 4.4%. No changes in prevalence were found when five-year cohorts of this group were analyzed, indicating that age-dependent changes or epidemiological factors do not result in a different (decreased) prevalence over the ages 35 to 55 years. The prevalence ofTrichomonas vaginalis and fungi, as detected by cytological screening, was lower than that observed forChlamydia trachomatis: 3.1 and 2.1%, respectively. Of the 109 smears positive forChlamydia trachomatis, 90 showed cervical cells with reactive changes (out of 1,490 smears with PAP II), whereas no cytological changes were found in 15 cases (out of 884 smears with PAP I). Changes suggestive of mild or moderate dysplasia were found in only four cases (out of 93 smears with PAP III). The results indicate thatChlamydia trachomatis is associated with reactive changes of endocervical cells and raise serious questions about whether prevention of possible secondary effects such as infertility and pelvic inflammatory disease can be achieved by a combined screening program for cervical cancer andChlamydia trachomatis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Infection 15 (1987), S. 125-127 
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Erwachsene syrische Hamster wurden auf intradermalem sowie auf oralem Infektionsweg nach lokaler Skarifizierung mit Herpes simplex-Virus Typ 1 (HSV-1) aus Mäusegehirn infiziert. Bei beiden Methoden wurden Symptome einer Beteiligung des Zentralnervensystems (ZNS) in der Periode zwischen fünf und 12 Tagen nach der Infektion beobachtet. Die ZNS-Beteiligung ist mit der intradermalen Infektion leichter auszulösen als durch Inokulation der Wangenschleimhaut. Mit einer Mindestdosis von 2 × 104 TCID50 Virus auf intradermalem Weg kann reproduzierbar eine Infektionsquote von mindestens 80% erreicht werden, was durch klinische Beobachtung leicht festzustellen ist. Deshalb ist eine serologische Überwachung der Immunreaktion für die Feststellung einer HSV-Infektion nicht erforderlich. Die Skarifizierung der Haut vor der Inokulation erwies sich als unabdingbar für die Auslösung einer intrazerebralen Infektion.
    Notes: Summary Adult Syrian hamsters were inoculated with a mouse brain passage of herpes simplex virus type 1 (HSV-1) along an intradermal and an oral route after local scarification. For both routes, clinical symptoms of central nervous system (CNS) involvement were seen in the period between five and 12 days post infection. Compared with the route via the buccal mucosa, CNS involvement by intradermal infection is easier to establish. With a minimum dose of 2 × 104 TCID50 virus via the intradermal route, an infection rate of 80% or more can be obtained reproducibly and detected simply by clinical observation without need of a survey of the humoral immune response. Scarification of the skin prior to inoculation was found to be essential for establishment of the CNS infection.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Adhärenz von Bakterien infolge spezifischer Oberflächeneigenschaften ist möglicherweise ein pathogenetischer Faktor in der Entwicklung der bakteriellen Endokarditis. Bestimmte Bakterientypen sind selektiv bevorzugt an der Entstehung dieser Erkrankung beteiligt. Es kann angenommen werden, daß Adhärenz und pathogene Mechanismen in Wechselwirkung treten, was sich auf die Entstehung der Endokarditis fördernd oder hemmend auswirken könnte. Beispiele einer solchen Interaktion, die zur Pathogenese der bakteriellen Endokarditis beitragen könnte, sind Dextranbildung durch Streptokokken, Aktivierung des Gerinnungssystems durch Gewebethromboplastin der Monozyten und die Phagozytose von Bakterien von der Oberfläche der Vegetationen durch Granulozyten und Monozyten.
    Notes: Summary Bacterial adherence as a result of specific surface properties may be a contributory factor in the pathogenesis of bacterial endocarditis giving certain types of bacteria a selective advantage to cause this disease. Adherence could interact with other pathogenetic mechanisms, and this interaction could promote or hamper the development of endocarditis. Dextran production by streptococci, the activation of the clotting system by monocyte tissue thromboplastin, and phagocytic removal of bacteria from the vegetational surface by granulocytes and monocytes are examples of interacting mechanisms that could contribute to the pathogenesis of bacterial endocarditis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...