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  • 1
    Electronic Resource
    Electronic Resource
    Cytokinetic behavior of Ehrlich ascites tumor after in vivo treatment with cis-diamminedichloroplatinum(II) and metallocene dichlorides (1981)
    Springer
    Journal of cancer research and clinical oncology 102 (1981), S. 21-30 
    Details
    ISSN: 1432-1335
    Keywords: cis-Diamminedichloroplatinum(II) ; Titanocene dichloride ; Vanadocene dichloride ; Ehrlich ascites tumor ; Pulse-cytophotometry ; cis-Diammindichloroplatin(II) ; Titanocen-dichlorid ; Vanadocen-dichlorid ; Ehrlich-Aszites-Tumor ; Impulscytophotometrie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Gegenstand der Untersuchungen ist der Einfluß einer in-vivo-Behandlung mit optimal tumorhemmenden Dosen von cis-Diammindichloroplatin(II) (DDP), Titanocen-dichlorid (TDC) und Vanadocen-dichlorid (VDC) auf das impulscytophotometrisch bestimmte DNA-Verteilungsmuster und die Mitoseaktivität von EAT-Zellen. Während DDP eine sofortige und langandauernde Unterdrückung der Zellteilungen, jedoch keine Veränderung des zellkinetischen Verhaltens von EAT-Zellen bewirkt, verursacht TDC die Ausbildung eines deutlichen,: 10–12 h nach Behandlung maximalen G2-Blocks. Im Falle von DDP und TDC werden die Tumorzellen einige Tage nach Behandlung durch Zellen des wirtstiereigenen Abwehrsystems beseitig. VDC hingegen ruft die Entstehung teilsynchroner Wellen nach einer vorübergehenden Mitosehemmung und einer reversiblen Zellakkumulation in der späten S-und der G2-Phase hervor. Darüber hinaus werden 5–16% der Zellen nach VDC-Behandlung polyploid.
    Notes: Summary The influence of an in vivo treatment with optimally tumor-inhibiting doses of cis-diamminedichloroplatinum(II) (DDP), titanocene dichloride (TDC), and vanadocene dichloride (VDC) on the DNA distribution pattern, determined by pulse-cytophotometry, and on the, mitotic activity of EAT cells is investigated. Whereas DDP causes an immediate and, long-lasting decrease of mitoses but no disturbances of the EAT cell kinetics, a marked G2 block with a maximum at 10–12 h a. t. and an irreversible and extensive mitotic depression is evoked by TDC. In the case of DDP and TDC, the tumor cells are removed several days a. t. by cells belonging to the defensive system of the host animals. In contrast, VDC induces partially synchronized waves after a transient suppression of mitoses and reversible cell accumulation in the late S and in the G2 phases. Additionally, 5–16% of the cells become polyploid after VDC treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00410531
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Different inhibition pattern of the nucleic acid metabolism (1981)
    Springer
    Naturwissenschaften 68 (1981), S. 272-273 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01047337
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  • 3
    Electronic Resource
    Electronic Resource
    Experimental test of electroweak effects at PETRA energies (1981)
    Springer
    The European physical journal 7 (1981), S. 289-293 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The differential cross sections for Bhabha scattering and μ pair production, and the total τ pair cross section as measured by the PLUTO detector at PETRA, have been analyzed to extract information on the weak interaction of leptons. The data are compared with unified gauge theories. Since the observed electroweak effects are still consistent with zero (within errors) we can set experimental limits on neutral current parameters atQ 2 values of 950 GeV2. In the framework of the standard SU(2)×U(1) model we find sin2 Θ w 〈0.52(95% c.l.). In the context of general singleZ o models we can excludeZ o masses of less than 40 GeV.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01431561
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  • 4
    Electronic Resource
    Electronic Resource
    Topology of the Υ-decay (1981)
    Springer
    The European physical journal 8 (1981), S. 101-114 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Multihadron events resulting frome + e − annihilation at the Υ-resonance are analysed with respect to lowest order QCD which predicts a dominant Υ decay into three vector gluons. Smearing effects due to the gluon fragmentation are so large, however, that no clear 3-jet structure or flatness is expected in the hadron final state. Instead, Monte Carlo simulations predict event structures with thrust and triplicity distributions distinctly different from those of two quark-jet and of phase space like decay mechanisms. The data are in perfect agreement with the 3-vector gluon decay as predicted by QCD and exclude dominantly phase space like or 2-quark jet decays. Also, the decay into scalar gluons is excluded by the data. An upper limit for the Υ-decay into one photon and two gluons is obtained.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01547873
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  • 5
    Electronic Resource
    Electronic Resource
    269. Ergebnisse von 178 Splenektomien (1981)
    Springer
    Langenbeck's archives of surgery 355 (1981), S. 630-630 
    Details
    ISSN: 1435-2451
    Keywords: Splenectomy ; Hodgkin's disease ; Werlhofs disease ; Ruptures ; Splenektomie ; M. Hodgkin ; M. Werlhof ; Rupturen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Lymphogranulomatose (n = 58): 25 Milzen befallen; 19 Patienten präop. falschem Stadium zugeordnet; von 45 Scintigraphien 10 falsch-positiv und 5 falsch-negativ befundet; von 42 Lymphographien 10 falsch-positiv und 6 falsch-negativ befundet; 2 Patienten verstorben. Rupturen (n = 39): 38 traumatisch, 1 spontan; 10 Patienten verstorben (alle mehrfachverletzt). M. Werlhof (n = 33): postop. Thrombocytenanstieg. Splenomegalie (n = 18): postop. Ery-, Leuko- und Thrombocytenanstieg; 1 Patient verstorben. Anämien (n = 16): Erythrocyten- und Hdmoglobinanstieg. Technische Gründe (n = 14).
    Notes: Summary Hodgkin's disease (n = 58): 25 spleens involved; in 19 patients the stage differed postoperatively; of 45 scintigrams, 10 false-positive and 5 false-negative; of 42 lymphangiograms, 10 false-positive and 6 falsenegative; 2 patients died. Ruptures (n = 39): 38 traumatic, 1 spontaneous; 10 patients died (all polytraumatized). Werlhofs disease (n = 33): increase of thrombocytes. Splenomegaly (n = 18): increase of erythrocytes, leucocytes and thrombocytes. Anaemia (n = 16): increase of erythrocytes and haemoglobin. 'latrogenic' reasons (n = 14).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01287102
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