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  • 1
    Electronic Resource
    Electronic Resource
    A simple method for elution of IgA deposits from the skin of patients with dermatitis herpetiformis (1989)
    Springer
    Archives of dermatological research 281 (1989), S. 406-410 
    Details
    ISSN: 1432-069X
    Keywords: Dermatitis herpetiformis ; Immunoglobulins ; Complement components ; Elution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To better understand the role of autoimmunity in the pathogenesis of dermatitis herpetiformis, linear IgA bullous dermatosis or other skin disorders, the antigenic specificity of the immune reactants bound in vivo in the skin must be identified. In order to do so, one must first be able to elute these immune reactants from the skin. We describe here a simple method of eluting not only specifically bound IgG, but also IgA and other immunoglobulins and complement components from skin biopsy material. The method involves cutaneous washing of the entrapped serum proteins in PBS pH 7 and pH 5 buffers followed by specific immunoglobulin elutions at pH 3 and 2. The IgA deposits which could not be removed by this treatment were eluted by a combination of low pH (0.5 M citrate pH 2) and a chaotropic agent (2 M NaCl). The relative concentration of IgA in eluates when quantitated by fluoroimmunoassay were three-to five-fold higher in dermatitis herpetiformis skin biopsy specimens, than in eluates of bullous pemphigoid or normal skin biopsy specimens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00455326
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  • 2
    Electronic Resource
    Electronic Resource
    Non-tuberculous mycobacterial lymphadenitis in children (1989)
    Springer
    European journal of pediatrics 148 (1989), S. 751-754 
    Details
    ISSN: 1432-1076
    Keywords: Lymphadenopathy ; Atypical mycobacteria ; Non-tuberculous mycobacterial lymphadenitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Eighty-six children (44 males, 42 females) were identified as having non-tuberculous mycobacterial lymphadenitis. The diagnostic criteria were either culture of the organism from the affected lymph node (n=68), or, when culture was negative, a positive skin test with non-tuberculous mycobacterial antigens and negative skin test responses to tuberculin purified protein derivative (PPD) in association with typical histological features (n=18). All children had histopathological findings of granulomatous inflammation with caseation and/or acid-fast bacilli. Eighty-two percent of the children were under 5 years of age at presentation and 30% were less than 2 years old. Most (79%) were city dwellers. Lymph node enlargement had been present for less than 6 months in almost all children (97.5%) and was almost exclusively in the face and neck region (97%). Disease was confined to the involved lymph nodes in 56% but had extended beyond the confines of the infected node to form a collar stud abscess in 38% and 6% presented with a skin sinus. Extranodal extension did not show any statistically significant association with the duration of lymphadenopathy. The duration of lymphadenopathy had been greater in those children in whom an organism was not isolated on culture resected tissue χ2, P〈0.01). All children were treated surgically, and recurrence occurred in five patients. This study describes the clinical and demographic characteristics of non-tuberculous mycobacterial lymphadenopathy in children in a population in which tuberculous adenitis is rare. Recognition of these features may allow earlier diagnosis and appropriate surgical therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00443102
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  • 3
    Electronic Resource
    Electronic Resource
    Comment on: "The infrared spectrum of the ν3 band of TiF4'' (1989)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 90 (1989), S. 5209-5210 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.456542
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  • 4
    Electronic Resource
    Electronic Resource
    Investigation of the electrical degradation of silicon Schottky contacts due to mercury contamination (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 55 (1989), S. 2331-2332 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A micrographic investigation of the effect of mercury exposure on silicon substrates was conducted. Mercury was found to leave a residue on the silicon surface. A further study was conducted to determine the extent of electrical degradation of Si Schottky contacts due to the presence of a contaminant mercury residue between the metal and the semiconductor. It was concluded that such a layer caused uncertainties in subsequent resistivity measurements, higher capacitance-voltage (C-V) barrier heights, and observable leakage currents in current-voltage (I-V) plots taken from mercury-contaminated Si Schottky diodes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.102052
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  • 5
    Electronic Resource
    Electronic Resource
    Study of oxygen addition to CF3Br reactive ion etching plasmas: Effects on silicon surface chemistry and etching behavior (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 54 (1989), S. 2321-2323 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The etching of silicon in CF3Br/O2 plasmas has been examined. In situ x-ray photoelectron spectroscopy shows that silicon surfaces etched in CF3Br/O2 plasmas with a proportion of 30% O2 or less are covered with a reaction layer that is mainly due to bromine bonded to silicon. As the proportion of oxygen is increased above 30% the reaction layer becomes thicker and contains mainly fluorine and oxygen, and the silicon etch rate decreases simultaneously.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.101115
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  • 6
    Electronic Resource
    Electronic Resource
    RNA/cDNA hybridization studies of UK isolates of barley yellow mosaic virus (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Plant pathology 38 (1989), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The RNA components of two isolates of BaYMV from Streatley and Wiltshire were analysed by agarose gel electrophoresis. Northern blots of extracts of both isolates analysed with random-primed cDNA probes to RNA1 and 2 of the Streatley isolate showed little or no sequence homologies between the two isolates, confirming other evidence that they should be considered as different viruses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3059.1989.tb02137.x
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  • 7
    Electronic Resource
    Electronic Resource
    Iliad 24.649: Another Solution (1989)
    Cambridge : Cambridge University Press
    The @classical quarterly 39 (1989), S. 247-250 
    Details
    ISSN: 0009-8388
    Source: Cambridge Journals Digital Archives
    Topics: Classical Studies
    Notes: J. T. Hooker argues that at Il. 24.649 ⋯πικερτομ⋯ων must mean ‘taunting’ and, since ‘taunting’ makes no sense, that ⋯πικερτομ⋯ων must have entered our Iliad at this point from a version of the Iliad slightly different from ours in which it did make sense. I wish to argue that ⋯πικερτομ⋯ων has a meaning different from ‘taunting’, which makes good sense of this, and every other, context.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S0009838800040623
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  • 8
    Electronic Resource
    Electronic Resource
    Innovation: Adaptation and Growth. (1989)
    Oxford, UK : Blackwell Publishing Ltd
    R & D management 19 (1989), S. 0 
    Details
    ISSN: 1467-9310
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-9310.1989.tb00658.x
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  • 9
    Electronic Resource
    Electronic Resource
    Cost benefit and public policy issues (1989)
    Oxford, UK : Blackwell Publishing Ltd
    R & D management 19 (1989), S. 0 
    Details
    ISSN: 1467-9310
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: AbstractThe paper reviews the work done and conclusions reached on resource allocation to R&D in the public sector in the last twenty years, and examines what changes have been made in the field of R&D assessment. The paper is based mainly on the author's experience with the UK government's Programmes Analysis Unit (PAU) which was set up in the early 1960s.The Unit's main remit was to examine and disseminate techniques by the use of which the benefit to the nation from possible R&D strategies, programmes and projects might be calculated. It was also called in to help review policy and carry out long-range forecasting. In the course of its existence — it was wound up in 1977 — it analysed many new techniques of analysis which have now passed into common use and took part in studies to support decisions at all levels from the macro-economic sector down to the individual project.The author lists the benefits derivable from such analyses — helping to identify objectives, assemble total programmes, evaluate efficiency of technological transfer, carry out technology assessment and so on. But he warns of their limitations.As for the present day, the author is unhappy about the importance given by the UK Government to the market as a test of value in decision-making about R&D, in so far as it leads to neglect of long-term issues and relies on uncertain causal relationships among critical inputs. Cost-benefit is adequate for dealing with short-term, small-scale projects. For larger projects with controversial long-term implications he advocates broader-based techniques such as multi-attribute analysis, which bring the interests of many parties into the judgment and take into account considerations such as the environment, finite resources and social
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-9310.1989.tb00633.x
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  • 10
    Electronic Resource
    Electronic Resource
    The dmfs and dmft of young South African children (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Community dentistry and oral epidemiology 17 (1989), S. 0 
    Details
    ISSN: 1600-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract – As part of a series of frequent epidemiological field studies to determine caries prevalences in the primary dentition of young South African children, 1436 children of 1–4 yr of age from five ethnic groups were examined. Using WHO diagnostic criteria decayed, missing, and filled surfaces were determined with mirror and probe and caries free, dmfs, dfs, ds, mfs, and dmft scores were calculated. The investigation has shown that urban coloured and Indian children have the highest caries prevalences and urban white children have the lowest. It is suggested that the percentage of caries-free children should be used to set goals for reduction in caries.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0528.1989.tb01824.x
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