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  • 1
    Electronic Resource
    Electronic Resource
    Human hair is a potential source of cat allergen contamination of ambient air (2005)
    Oxford, UK : Munksgaard International Publishers
    Allergy 60 (2005), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  We have previously shown that airborne cat allergen levels are significantly lower in school classes using special school clothing or in classes with no pet owners. However, cat allergen is present and the levels are in fact two- to threefold higher on cat owners’ than noncat owners’ school clothing which is used, washed and stored at school only. This suggests that allergen is transferred to schools by routes other than clothing.Aim:  To analyse levels of cat allergen (Fel d 1) in hair from cat owners and noncat owners among children and adults.Methods:  Samples of unwashed hair (≥1 day prior to sampling) from adults and children with (n = 22) or without (n = 22) cats at home were collected at a hairdresser. In addition, samples of newly washed hair (adults only, n = 11) were collected. The hair sample was extracted and analysed for Fel d 1 content with ELISA.Results:  The geometric mean levels were more than two orders of magnitude higher in unwashed hair from cat owners, compared with noncat owners (P 〈 0.0001) and more than 10-fold higher in newly washed hair from adults. The allergen contamination of unwashed hair among noncat owners appeared higher in children than in adults (P = 0.045).Conclusions:  Hair may be an important source for transfer and deposition of cat allergen in schools and may explain why cat allergen is found in environments with strict allergen avoidance measures. Although it may be unrealistic to apply allergen avoidance strategies against this allergen source, it is important to be aware of it.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.2005.00796.x
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  • 2
    Electronic Resource
    Electronic Resource
    Lack of correlation between NADPH-oxidase priming and elevated alkaline phosphatase activity in cord blood neutrophils (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Pediatric allergy and immunology 6 (1995), S. 0 
    Details
    ISSN: 1399-3038
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Human neutrophils were isolated from cord blood drawn after Caesarean section deliveries without labour and from peripheral blood from healthy adults. The alkaline phosphatase (ALP) activity in the cell populations was compared with the release of respiratory burst products after activation with the chemoattractant n-formyl-methionyl-leucyl-phenylalanine (fMLP). In contrast to cord blood neutrophils obtained from babies after normal vaginal deliveries, the Caesarean section neutrophils were not metabolically primed. However, like the neutrophils from vaginally delivered babies, the Caesarean section neutrophils showed an increased ALP activity compared to adult control neutrophils. These findings indicate that priming of cord blood neutrophils appears to be induced by labour and can be dissociated from increased ALP activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1399-3038.1995.tb00276.x
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  • 3
    Electronic Resource
    Electronic Resource
    On-Plant Test of TÜV HCM12 and ASME T23 Alloys for Use as Water Wall Materials (1999)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 171-174 (Oct. 1999), p. 169-178 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/45/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.171-174.169.pdf
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  • 4
    Electronic Resource
    Electronic Resource
    Estramustine-binding protein in meningioma (1999)
    Springer
    Acta neuropathologica 98 (1999), S. 135-140 
    Details
    ISSN: 1432-0533
    Keywords: Key words Prostatic binding protein ; Brain tumor ; Chemotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The presence of estramustine-binding protein has been suggested to positively correlate with the effect of the cytotoxic drug estramustine, a combination of estradiol and nornitrogen mustard used in the treatment of prostatic carcinoma. This study demonstrates expression of estramustine-binding protein in a series of meningioma using different ligand-based and immunological techniques. Scatchard plot analysis showed specific binding sites for [3H]estramustine in meningioma tissue with a dissociation constant of 22–26 nM. Immunohistochemistry revealed an immunoreactivity in meningioma comparable to that demonstrated in prostatic carcinoma. The mean concentration (n = 6) of estramustine-binding protein in meningioma, as determined by radioimmunoassay was 159 ng/g tissue (range 18–274 ng/g). Moreover, partial characterization using size exclusion chromatography of [3H]estramustine-labeled tumor extracts and Western blot analysis of immunoprecipitated samples indicated that the structure of the estramustine-binding protein in meningioma is similar to that in rat prostate, with three polypeptide components of 10, 14, and 16 kDa, as compared to 8, 10–11, and 12 kDa in rat prostate. In conclusion, the novel observation of estramustine-binding protein and specific binding of estramustine in meningioma justify further evaluation regarding the role of estramustine-binding protein in the growth behavior of meningioma and the potential for estramustine and similar hormone-related drugs in the treatment of relapsing meningioma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010051061
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  • 5
    Electronic Resource
    Electronic Resource
    A New Bone Dust Packer for Use in Neurosurgery (1999)
    Springer
    Acta neurochirurgica 141 (1999), S. 183-185 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: Bonedust; craniotomy; burrhole; skindent.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  A new tool for the packing of bone dust has been developed. The instrument compresses a mixture of bone dust and saline into suitable cylindrical plugs, fitting neatly into craniotomy burrholes. The skullbone at the craniotomy area will heal neatly also assuring the best healing possibilities for the overlying skin. The cosmetic results are excellent as no skin dents or cavities will be formed over the burrholes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010050284
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  • 6
    Electronic Resource
    Electronic Resource
    Anaerobic degradation of xenobiotics by organisms from municipal solid waste under landfilling conditions (1996)
    Springer
    Antonie van Leeuwenhoek 69 (1996), S. 67-74 
    Details
    ISSN: 1572-9699
    Keywords: biodegradation ; chlorinated compounds ; freons ; methane formation ; phthalic acid esters ; phenol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The potential for biological transformation of 23 xenobiotic compounds by microorganisms in municipal solid waste (MSW) samples from a laboratory scale landfill reactor was studied. In addition the influence of these xenobiotic compounds on methanogenesis was investigated. All R11, 1,1 dichloroethylene, 2,4,6 trichlorophenol, dimethyl phthalate, phenol, benzoate and phthalic acid added were completely transformed during the period of incubation (〉 100 days). Parts of the initially added perchloroethylene, trichloroethylene, R12, R114, diethyl phthalate, dibutyl phthalate and benzylbutyl phthalate were transformed. Methanogenesis from acetate was completely inhibited in the presence of 2,5 dichlorophenol, whereas 2,4,6 trichlorophenol and R11 showed an initial inhibition, whenafter methane formation recovered. No transformation or effect on the anaerobic microflora occurred for R13, R22, R114, 3 chlorobenzoate, 2,4,6 trichlorobenzoate, bis(2 ethyl)hexyl phthalate, diisodecyl phthalate and dinonyl phthalate. The results indicate a limited potential for degradation, of the compounds tested, by microorganisms developing in a methanogenic landfill environment as compared with other anaerobic habitats such as sewage digestor sludge and sediments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00641613
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  • 7
    Electronic Resource
    Electronic Resource
    Comparison of experimental, calculated and observed values for electrical and thermal conductivity of aluminium alloys (1997)
    Springer
    Journal of materials science 32 (1997), S. 4383-4390 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A model has been developed for calculating the electrical resistivity of commercial aluminium alloys from composition and heat treatments using the Matthiessen rule. The model is based on the approximation that the solubility of the alloying elements in heat treated alloys is equivalent to the equilibrium solubility at a higher temperature. These temperatures were determined from heat treatment data. The resistivity of a wide range of commercial alloys was calculated using the model, showing an agreement with most observed resistivity values of within 3 nΩm, except for alloys with special composition characteristics. According to the model, magnesium and manganese are important contributors to the resistivity for all main groups of alloys. In heat treated alloys the contribution of precipitates is 6–17% of the total resistivity. Thermal conductivity was calculated for alloys given in the literature using the Wiedeman–Franz law and the calculated resistivity. The calculated thermal conductivity agreed with the experimental values for the AlMg-alloys, but it was lower than the experimental values for pure aluminium and the AlCu-alloys in the annealed condition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018680024876
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  • 8
    Electronic Resource
    Electronic Resource
    Magnetic-field-induced semiconductor-semimetal transition in Bi-Sb alloys (1970)
    Springer
    Journal of low temperature physics 3 (1970), S. 147-174 
    Details
    ISSN: 1573-7357
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Accurate and detailed measurements of the temperature dependence of the longitudinal magnetoresistance of single-crystal Bi-Sb alloys have been made, with static magnetic fields in the range 0–100 kG oriented parallel to the trigonal axis. Alloy concentrations were in the range 8–12 at.% Sb, and temperatures in the range 1–35 K. At very high fields the resistance increases with increasing temperature in a metallic manner with “ideal” and “residual” components, in contrast to the semiconductor behavior observed at zero field or low fields. For the high-field semimetal regime the electrical resistance behaves in a simple manner similar to a metal in zero field, in contrast to the complicated magnetoresistance phenomena for metals in low fields. This behavior can be understood in terms of a simple quasi-one-dimensional extreme-quantum-limit regime. The magnetic-field-induced semiconductor-semimetal transition is associated with an energy gap and changes of the energy-band structure which are of order 1 meV. Thermal activation energies for electrical conduction manifest this gap only at temperatures below approximately 20 K. Activation energies an order of magnitude larger which have been measured at considerably higher temperatures are apparently the direct gap at theL-point in the Brillouin zone and are not directly connected with the semiconductor-semimetal transition. Our results indicate that the zero-field indirectL-T energy gap increases from zero somewhere near 7–8 at. % Sb to values only as large as approximately 1.5 meV at 12 at. % Sb. At the magnetic-field induced transition there occurs evidence of an intermediate “excitonic insulator” phase, a resistance minimum below 10 K reminiscent of the Kondo alloy behavior. This anomalous regime is a property of the semiconductor-to-semimetal transition and cannot be associated with the well-known temperature and magnetic-field “freeze-out” of charge carriers in extrinsic semiconductors, or with magnetic ordering of the Kondo type.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00628324
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  • 9
    Electronic Resource
    Electronic Resource
    The use of mobile phase pH and column temperature to reverse the retention order of enantiomers on chiral-AGP® (1998)
    Springer
    Chromatographia 47 (1998), S. 189-196 
    Details
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Experimental design ; Mosapride ; Reversal of retention order ; Effect of pH and column temperature
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Enantiomeric separation of mosapride and a structurally related compound was performed using chiral chromatography and experimental design. Unique effects of mobile phase pH and column temperature made it possible to control the elution order of the enantiomers when using Chiral-AGP as the solid phase. At a low mobile phase pH (〈6) the (R)-enantiomer of mosapride elutes before the (S)-form whereas the (S)-enantiomer elutes first at a high mobile phase pH (〉6). By using a mobile phase pH around 6, the column temperature could also be used to control the elution order of the enantiomers of mosapride. Similar effects of mobile phase pH and column temperature were obtained for the enantiomers of a structurally related compound, a metabolite (M1). Isocratic chromatographic systems made it possible to determine enantiomeric impurities less than 0.1% in the respective enantiomer of mosapride. The enantiomers of mosapride as well as the enantiomers of M1 could easily be separated simultaneously using Chiral-AGP and a simple gradient elution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02466580
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  • 10
    Electronic Resource
    Electronic Resource
    Optimisation of chiral separation of omeprazole and one of its metabolites on immobilized α1-acid glycoprotein using chemometricsglycoprotein using chemometrics (1997)
    Springer
    Chromatographia 44 (1997), S. 10-18 
    Details
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Experimental design ; Direct chiral resolution ; Omeprazole ; Hydroxy-omeprazole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A strategy for the optimisation of direct chiral separation of omeprazole and a metabolite, hydroxi-omeprazole, in reversed phase liquid chromatography is described. A factorial design was used, where mobile phase pH, concentration of a mobile phase modifier, ionic strength and column temperature were tested as the variables and enantioselective retention, column efficiency and asymmetry factor as the responses. The experimental results were evaluated with multivariate analyses, which demonstrated that the column temperature and content of mobile phase acetonitrile were by far the most important variables. The enantiomers of omeprazole and one of its metabolites were baseline resolved within 15 minutes. The optimised chromatographic system was used for a separation of the enantiomers of omeprazole and its main metabolite in a patient plasma sample.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02466509
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