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  • 1
    ISSN: 1432-0568
    Keywords: Neuropeptide Y ; Substance P ; Immunocytochemistry ; C-fibers ; Dura mater ; Dural sinus ; Meningeal arteries ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Density and pattern of nerve fibers with neuropeptide Y-like immunoreactivity (NPY-LI) and substance P-like immunoreactivity (SP-LI) in the rat dura mater encephali were investigated by light and electron microscopy using whole-mount preparations. NPY-LI fibers are observed throughout the encephalic dura mater. A remarkable net of NPY-LI nerve fibers is located in the walls of the sagittal and transverse sinuses. Beyond that NPY-LI network, distinct NPY-LI nerve fibers or plexus occur in the rostral falx, parietal dura mater of the olfactory bulb, supratentorial dura mater, parietal dura mater of the cerebellum, tentorium cerebelli and the ventral dura mater. Electron microscopic studies reveal that NPY-LI is exclusively located in unmyelinated axons of small and large nerve fiber bundles, with or without a perineural sheath. Immunopositive C-fibers are predominantly associated with the vascular bed. SP-LI nerve fibers have a moderate and more uniform distribution in the encephalic dura mater. A distinct plexus of SP-LI fibers follows the branches of the middle meningeal artery and the adjacent dura mater. SP-LI fibers are most prominent in the parietal dura mater of the cerebellum. Fine beaded SP-LI fibers, arising from larger SP-LI fiber bundles, are observed in close association to the capillary bed. SP-LI axons are all unmyelinated. They are found in larger nerve fiber bundles with a perineural sheath or in Schwann cells lacking any perineural sheath. The function of NPY-LI and SP-LI nerve fibers in the rat dura mater is discussed in relation to their topography, density and termination.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0568
    Keywords: Tachyglossus aculeatus (echidna) ; Echidna bill ; Sensory receptors ; Electroreceptor ; Mechanoreceptor ; Trigeminal nerve ; Monotreme ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The gross anatomy and nerve supply of the bill of echidna (Tachyglossus aculeatus) is described in relation to its function as an outstanding sensory organ. The sensory innervation of the skin of the echidna snout was investigated by means of frontal serial sections, after decalcification of the specimens. A comprehensive light and electron microscopic description of the location and fine structure of cutaneous sensory receptors of the trigeminal system was made by this means. The encapsulated and non-encapsulated Ruffini receptors, the types of other free receptors in the connective tissue and the Merkel cell receptor do not differ morphologically from those of higher mammals, whereas the pacinian-like corpuscle shows a unique organization of its outer core. This is composed of large perineural cells containing a unique reticulum of parallel-orientated endoplasmic membranes. Lamellated corpuscles, seen in isolation or in association with push rods, are numerous in the snout and in the tip of the tongue of echidna. Push rod receptor organs occur in the hairless skin of the bill with a very dense array at its rostral end and in the pseudopalatal ridges. Gland duct receptors are restricted to the skin adjacent to the nostrils and the mouth opening, including the pseudopalatal plates. Only about one quarter of the total number of 400 seromucous glands receive a sensory innervation of their intraepidermal duct segment. Within each innervated gland two types of receptor terminals are identified. The distributions of the different receptor types are mapped for different regions of the skin, the mucous membrane of the nasal and oral vestibule and the tip of the tongue. The fine structure of nerve terminals is discussed from a comparative anatomical point of view, and some speculations are made about possible transduction processes that underlie the known electrophysiological properties. The sensory organs such as the “push rod” and “gland duct receptor”, and most of their sensory terminals, are less differentiated in echidna snout than in the platypus (Ornithorhynchus anatinus) bill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Journal of metastable and nanocrystalline materials Vol. 15-16 (Apr. 2003), p. 279-282 
    ISSN: 1422-6375
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1090-6509
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Quantum oscillations of de Haas-van Alphen and Shubnikov-de Haas and semiclassical angular oscillations of the magnetoresistance have been observed in the quasi-two-dimensional organic metal α-(BETS)2TlHg(SeCN)4. The quantum oscillations are connected with the cylindrical part of the Fermi surface. The angular oscillations are associated with the carrier motion on both the cylindrical part and quasi-planar sheets of the Fermi surface. The values of the Dingle temperature, T D ≈ 2–3 K, and the effective mass, m* ≈ 1.03m 0, have been defined. The possibility of the weakening of multibody interactions has been shown in this compound.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Background  Imiquimod 5% cream has been investigated for non-surgical treatment of superficial and nodular basal cell carcinoma (BCC) tumours. Objectives  Two studies were conducted to examine the effect of occlusion at low dosing frequencies on the safety and efficacy of topical imiquimod 5% cream for the treatment of superficial and nodular BCC. Patients and methods  Both open-label studies were conducted in Europe. Patients diagnosed with BCC were enrolled into either the superficial (93 patients) or nodular (90 patients) study, depending on the histological confirmation of the patient's tumour subtype. Patients were randomized to one of four groups to apply imiquimod 5% cream 2 or 3 days per week either with or without occlusion. Six weeks following a 6-week treatment period, the entire target tumour area was excised and histologically examined for evidence of residual tumour. Results  In both studies, the highest histologically complete response rate was seen in the 3 days per week with occlusion groups, with complete response rates of 87% and 65% for the superficial and nodular studies, respectively. Occlusion did not have a statistically significant effect on response rate at either dosing frequency. Response rates for superficial and nodular BCC tumours treated 3 days per week without occlusion were 76% and 50%, respectively. Conclusions  In the superficial study, the complete response rate of 87% in the 3 days per week with occlusion group was similar to that of daily and 5 days per week dosing without occlusion in a previous 12-week study and one study of daily dosing without occlusion for 6 weeks. All treatment groups had acceptable safety profiles in both studies. Occlusion did not have a statistically significant effect on efficacy for either superficial or nodular BCC tumours.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 82 (1991), S. 243-255 
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We present results of a series of high resolution, low fielddc-magnetization measurements on the heavy fermion superconductors UPt3, UBe13, U1−x Th X Be13 and CeCu2Si2, from which values of the magnetic penetration depth λ can be extracted. A study of the temperature variation reveals aT 2 power law in all cases. This can not be reconciled with a BCS-like isotropic energy gap but may be explained by the presence of low energy quasiparticle states inside the gap. In the case of very pure superconductors, one such possibility is the assumption of point-nodes in the gap function. We argue, however, that an interpretation in terms of resonant impurity scattering in various anisotropic superconducting states is more likely to explain a broad range of experimental data. The results on differently oriented single crystals of UBe13 and UPt3 reveal no pronounced anisotropy related to the crystal lattice. Absolute values of λ atT=0 are deduced by a novel method in which the field is first screened out from the sample by means of an evaporated superconducting film (of lowerT c ). Above this lowerT c the sudden penetration of field into the sample can then be measured absolutely.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1572-9605
    Keywords: Organic superconductor ; reentrant superconductivity ; temperature-pressure phase diagram ; magnetic-field-induced phase transition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Abstract Systematic experimental study of the electrical transport and static magnetization reveals a direct and delicate interplay between magnetism and superconductivity in the organic materialκ-(BEDT-TTF)2Cu[N(CN)2]Cl, displayed through the specific temperature-pressure phase diagram, and such new effects for organic solids as the reentrant superconductivity in zero applied magnetic field and high-field-induced interchange between superconductivity and the nonmetallic resistive phase in the high-pressure region.
    Type of Medium: Electronic Resource
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