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  • 1
    Electronic Resource
    Electronic Resource
    Plagioclase replacement textures in partially eclogitised gabbros from the Sanddal mafic-ultramafic complex, Greenland Caledonides (2001)
    Oxford, UK : Blackwell Science Inc
    Journal of metamorphic geology 19 (2001), S. 0 
    Details
    ISSN: 1525-1314
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: The Sanddal mafic-ultramafic complex (SMUK) is a cluster of variably eclogitised mafic and ultramafic bodies that comprise the westernmost known eclogite facies locality in the North-East Greenland eclogite province (NEGEP). Although there are no true eclogites in the SMUK, we interpret three distinct textural types of plagioclase replacement to record sequential stages in adjustment of SMUK olivine gabbro-norites to eclogite facies conditions. The earliest stage, in which plagioclase was replaced by omphacite/spinel symplectite before nucleation of garnet (Type 1A & 1B) has not previously been described. Documentation of this texture provides clear evidence that, at least in some cases, garnet nucleation is delayed relative to nucleation of omphacite and is a rate-limiting step for eclogitisation. Type 1C domains were produced by scattered nucleation of garnet in the same sample. In Type 2 domains, plagioclase was replaced by a layered corona with an outer layer of garnet, an inner layer of omphacite and an interior of inclusion-rich plagioclase. In Type 3 domains, the omphacite layer was overgrown by the garnet rim, and omphacite is preserved only as inclusions in garnet. In more coarse grained leucogabbros, recrystallization was more complete, plagioclase replacement textures were less localised, and could not be divided into distinct stages. Plagioclase replacement in SMUK samples was not isochemical, and required diffusion of at least Mg and Fe from replacement of mafic phases in the surroundings. Strong compositional gradients in garnet reflect disequilibrium and were controlled by the different diffusion rates of Mg/Fe and Ca, different local chemical environments, and progress of the plagioclase breakdown reaction. The presence of small amounts of hydrous minerals (amphibole, phlogopite and clinozoisite) in local equilibrium in plagioclase domains of most SMUK samples indicates that a small amount of H2O was present during high pressure metamorphism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.0263-4929.2001.00325.x
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  • 2
    Electronic Resource
    Electronic Resource
    Current patterns of irritable bowel syndrome in Taiwan: the Rome II questionnaire on a Chinese population (2003)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 18 (2003), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : Irritable bowel syndrome is a common condition seen in Western countries. In Asia, however, it is less known and even less studied.Aim : To determine the prevalence and social impact of irritable bowel syndrome as well as the health-seeking behaviour of irritable bowel syndrome patients in TaiwanMethods : Using the modified Rome II questionnaire, a survey was carried out in a population receiving physical check-up (n = 2865).Results : The prevalence of irritable bowel syndrome in Taiwan was 22.1% and 17.5% (κ = 0.73) according to the Rome II and I criteria, respectively. No gender difference was found between subjects with and without irritable bowel syndrome symptoms. Irritable bowel syndrome subjects were likely to undertake an excessive number of physician-visits (P 〈 0.01). Such subjects were often absent from work/school, with more days of absenteeism than irritable bowel syndrome-free subjects (P 〈 0.01). They also suffered obvious sleep disturbance (P 〈 0.01). Nearly half of the irritable bowel syndrome subjects were ‘consulters’, and they were more likely to have frequent physician-visits, suffer from work/school absenteeism, and endure sleep disturbance and bowel symptoms than irritable bowel syndrome nonconsulters (P 〈 0.05).Conclusions : Irritable bowel syndrome is common in a Chinese population of Taiwan. Similar to irritable bowel syndrome in the West, it also involves significant social and medical burdens. However, in the irritable bowel syndrome subjects of Taiwan there is no gender difference, and more irritable bowel syndrome subjects will seek physician consultations, which may be due to Taiwan's easily accessible and affordable heath care facilities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2003.01711.x
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  • 3
    Electronic Resource
    Electronic Resource
    Leberresektion und Lebertransplantation als Therapie primärer Lebertumoren (2000)
    Springer
    Der Onkologe 6 (2000), S. 311-317 
    Details
    ISSN: 1433-0415
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Die Leberchirurgie hat in den letzten 15 Jahren wesentliche Fortschritte erzielen können. Ursächlich hierfür sind nicht zuletzt operationstechnische Verbesserungen, wie beispielsweise die Anwendung der bei einer Lebertransplantation erforderlichen organprotektiven Maßnahmen auch in der Resektionschirurgie. Weiterhin trugen ebenso Fortschritte in der perioperativen Intensivtherapie entscheidend zur Entwicklung der Leberchirurgie bei. Eine zentrale Rolle kommt den diagnostischen Verfahren beim präoperativen Tumorstaging sowie bei der Differentialdiagnose solider primärer Lebertumoren zu. Durch die moderne bildgebende Technik kann in aller Regel zwischen benignen und malignen Lebertumoren unterschieden und darüber hinaus in Kombination mit dem klinischen Erscheinungsbild auch eine weitere Unterteilung der häufigsten benignen Lebertumoren erfolgen. Die Bestimmung von Tumormarkern läßt zudem nicht selten auch einen Rückschluss auf die Histologie primärer maligner Lebertumoren zu. Eine Biopsie sollte immer dann vermieden werden, wenn durch die bildgebende Diagnostik in Verbindung mit den Tumormarkern eine sichere Diagnostik möglich ist. Malignitätsverdächtige Tumore erfordern ohnehin eine Operation, sofern dies der Zustand des Patienten und das weitere Staging erlauben. Lediglich bei inoperablen Tumoren unklarer Histologie ist zur Planung der weiteren nichtoperativen Therapie die Klärung der Dignität mittels Biopsie unbedingt anzustreben. Die vorliegende Arbeit gibt einen Überblick über den gegenwärtigen Stand der chirurgischen Therapie für die wichtigsten benignen Leberveränderungen sowie für das hepatozelluläre und cholangiozelluläre Karzinom.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007610050509
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  • 4
    Electronic Resource
    Electronic Resource
    Ex-vivo resection techniques in tissue-preserving surgery for liver malignancies (2000)
    Springer
    Langenbeck's archives of surgery 385 (2000), S. 179-184 
    Details
    ISSN: 1435-2451
    Keywords: Key words Resection techniques ; Tissue-preserving surgery ; Liver malignancies ; Ex-vivo ; Ex situ
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Some primary and secondary liver tumours are not absolutely irresectable, but cannot be resected using a conventional approach because of the limited warm ischaemia tolerance of the liver or poor accessibility of the tumour region. In such situations, the techniques of ex vivo liver surgery, pioneered by Rudolf Pichlmayr some 10 years ago, offer new chances for R0 resection. All the three different approaches, namely ”in situ”-, ”ante situm”-, and ”ex situ” resection, require the use of measures originally developed for transplantation, such as hypothermic liver perfusion and veno-venous bypass. They differ mainly in the extent to which major vessels are divided in order to achieve optimal mobility of the organ. The results show that radical resection can be achieved accomplished in many cases. If necessary, complex vascular reconstructions can be performed. Although perioperative morbidity and mortality are high, there are a number of long-term survivors. Tumour recurrence, however, remains the main problem over the long term. In conclusion, ex vivo liver surgery is an important extension of surgical treatment possibilities. However, the procedure is suitable only for a small number of carefully selected patients and should be reserved for use in specialised centres. Furthermore, in view of the fact that the results are not yet optimal, additive and adjuvant treatment modalities are needed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004230050262
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