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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of nonlinear science 10 (2000), S. 661-685 
    ISSN: 1432-1467
    Keywords: Key words. thin film elasticity, blistering, von Kármán theory of plates, optimal scaling laws
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Summary. We study the Föppl—von Kármán theory for isotropically compressed thin plates in a geometrically linear setting, which is commonly used to model weak buckling of thin films. We consider generic smooth domains with clamped boundary conditions, and obtain rigorous upper and lower bounds on the minimum energy linear in the plate thickness σ . This energy is much lower than previous estimates based on certain dimensional reductions of the problem, which had lead to energies of order 1+σ (scalar approximation) or σ 2/3 (two-component approximation).
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 12 (2000), S. 0 
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Individuals suffering from classical migraine report an astonishing diversity of migraine auras. A frequently reported symptom is a visual hallucination known as fortification illusion (FI). Here we demonstrate that the typical zig-zag pattern of the FI can be reproduced using experimental data of orientation maps of the primary visual cortex (V1) assuming that a continuous excitation front propagates across V1. We put forward a model in which the cortical neurons within this excitation wave are activated sufficiently to contribute to conscious perception. It is shown that the discontinuous repetitive nature of the zig-zag pattern of the FI can reflect the specific layout of visual cortical orientation maps. Additionally, dynamic features of the FI are predicted based on our model.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: DivIVA from Bacillus subtilis is a bifunctional protein with distinct roles in cell division and sporulation. During vegetative growth, DivIVA regulates the activity of the MinCD complex, thus helping to direct cell division to the correct mid-cell position. DivIVA fulfils a quite different role during sporulation in B. subtilis when it directs the oriC region of the chromosome to the cell pole before asymmetric cell division. DivIVA is a 19.5 kDa protein with a large part of its structure predicted to form a tropomyosin-like α-helical coiled-coil. Here, we present a model for the quaternary structure of DivIVA, based on cryonegative stain transmission electron microscopy images. The purified protein appears as an elongated particle with lateral expansions at both ends producing a form that resembles a ‘doggy-bone’. The particle mass estimated from these images agrees with the value of 145 kDa measured by analytical ultracentrifugation suggesting 6- to 8-mers. These DivIVA oligomers serve as building blocks in the formation of higher order assemblies giving rise to strings, wires and, finally, two-dimensional lattices in a time-dependent manner.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 264-268 (May 2004), p. 1383-1386 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1433-0415
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: In den letzten Jahrzehnten hat sich der Stellenwert der Strahlentherapie bei der Behandlung pädiatrischer Tumoren gewandelt. Fortschritte auf dem Gebiet strahlentherapeutischer Techniken und Kenntnisse über notwendige Dosierungen für eine maximale Tumorkontrolle bei minimaler Nebenwirkungsrate (Dosis-Wirkungs-Beziehungen) erlauben eine effiziente und schonende Bestrahlung mit Anhebung der Überlebenszeiten bei gleichzeitiger Reduktion von Therapiefolgen, ohne jedoch die Metastasierungstendenz wesentlich zu beeinflussen. Die Einführung von Chemotherapien erreichte eine zusätzliche systemische Tumorkontrolle, sodass heute bei der überwiegenden Mehrheit der Erkrankungen Heilungsraten erzielt werden, die 70% übersteigen (Tabelle 1). Während im Erwachsenenalter vorwiegend Tumoren epithelialen Ursprungs im Vordergrund stehen, werden Tumoren im Kindesalter vorwiegend durch Neoplasien embryonaler Genese gebildet. Diese zeigen eine erhöhte Empfindlichkeit gegenüber ionisierender Strahlung und chemotherapeutischen Substanzen. Hierdurch werden die im Vergleich zum Erwachsenenalter deutlich erhöhten Heilungsraten erklärt. Gleichzeitig reagiert aber der wachsende Organismus sensibler auf zytotoxische Agenzien. Einige chemotherapeutische Substanzen können zwar durch einen strahlensensibilisierenden Effekt die Tumorkontrolle verbessern, erhöhen jedoch gleichzeitig das Risiko für akute, maximale Nebenwirkungen und Spätfolgen (Tabelle 2). Hierdurch können nicht nur einzelne Organfunktionen beeinträchtigt werden, sondern auch die gesamte Entwicklung des betroffenen Kindes. Die Dosisschwelle für die Toleranz des kindlichen Gewebes v. a. der sich entwickelnden Organe liegt häufig unter den Dosierungen, die für die lokale Tumorkontrolle notwendig sind, und ändern sich durch eine zusätzliche Chemotherapie. Daher werden spezielle Anforderungen an die Strahlentherapie gestellt, um Normalgewebe und v. a. Risikoorgane zu schonen.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    HNO 48 (2000), S. 477-480 
    ISSN: 1433-0458
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Im letzten Teil unserer Notfallmanagement-Reihe wird nochmal praxisbezogen und für den notfallmedizinisch ungeübten Arzt auf relevante Notfallsituationen in der HNO-Praxis eingegangen. Dargestellt werden in dieser Ausgabe die folgenden Notfallsituationen in alphabetischer Reihenfolge: ·Herzinfarkt ·Hyperventilationstetanie ·Hypoglykämie ·Krampfanfall ·Lungenödem ·Schlaganfall ·Vasovagale Synkope
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    HNO 48 (2000), S. 323-329 
    ISSN: 1433-0458
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Notfallsituationen in der HNO-ärztlichen Praxis sind zwar selten, dann aber stellen sie den Arzt und seine Mitarbeiter vor eine Situation, auf die er in der Regel nicht ausreichend vorbereitet ist. Organisatorisches Chaos und teilweise Hilflosigkeit sind die Folgen, die unter medizinischen, aber auch unter juristischen Aspekten zu fatalen Konsequenzen führen können. Ein richtiges Handeln in Notfallsituationen ist dabei nicht schwer, wenige grundlegende Maßnahmen können Ihren Patienten und Sie absichern.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    HNO 48 (2000), S. 401-404 
    ISSN: 1433-0458
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Im Folgenden werden einige für die HNO-Praxis relevante Notfallsituationen und ihre Behandlungsmöglichkeiten in Kurzform dargestellt. Die Therapieschemata wurden dabei bewusst so gewählt, dass diejenigen Maßnahmen, die auch vom notfallmedizinisch ungeübten Arzt oder seinen Mitarbeitern ohne aufwendige invasive Methoden durchgeführt werden können, im Vordergrund stehen. Dargestellt werden in dieser Ausgabe der “HNO” die folgenden Notfallsituationen in alphabetischer Reihenfolge: · Anaphylaktischer Schock · Angina pectoris · Akuter Asthmaanfall · Bluthochdruck mit Hypertensiver Krise · Blutungen · Bolusgeschehen
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 34 (2003), S. 305-319 
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We reason in support of the universality of quantum spectral fluctuations in chaotic systems, starting from the pioneering work of Sieber and Richter who expressed the spectral form factor in terms of pairs of periodic orbits with self-crossings and avoided crossings. Dropping the restriction to uniformly hyperbolic dynamics, we show that for general hyperbolic two-freedom systems with time-reversal invariance the spectral form factor is faithful to random-matrix theory, up to quadratic order in time. We re late the action difference within the contributing pairs of orbits to properties of stable and unstable manifolds. In studying the effects of conjugate points, we show that almost self-retracing orbit loops do not contribute to the form factor. Our findings are substantiated by numerical evidence for the concrete example of two billiard systems.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 34 (2003), S. 285-292 
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. One- and two-component bistable reaction-diffusion systems under external force are considered. The simplest case of a periodic forcing of cosine type is chosen. Exact analytical solutions for the traveling fronts are obtained for a piecewise linear approximation of the non-linear reaction term. Velocity equations are derived from the matching conditions. It is found that in the presence of forcing there exists a set of front solutions with different phases (matching point coordinates $\xi_0$ ) leading to velocity dependencies on the wavenumber that are either monotonic or oscillating. The general characteristic feature is that the nonmoving front becomes movable under forcing. However, for a specific choice of wavenumber and phase, there is a nonmoving front at any value of the forcing amplitude. When the forcing amplitude is large enough, the velocity bifurcates to form two counterpropagating fronts. The phase portraits of specific types of solutions are shown and briefly discussed.
    Type of Medium: Electronic Resource
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