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  • 2000-2004  (4)
  • 1
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Laser ion source (LIS) is the most intense source of highly charged ions to fill the synchrotron rings in a single turn injection mode. For this reason LIS is used for ITEP TerraWatt Accumulator (TWAC) facility aiming at the production of TerraWatt power level (100 kJ/100 ns) of intense ion beams. Total current density, charge state distribution, and emittance of carbon ion beam generated by the 5 J/0.5 Hz rep-rate CO2 laser were measured at the exit of the source. A low energy beam transport line (LEBT) consisting of Einzel lenses and a buncher were used to match the source to 2 MV/2.5 MHz injector I-3. The C+4 ion beam with current up to 5 mA was accelerated by injector I–3 and about half of this amount have been injected into booster synchrotron. LIS was operated with rep-rate of 0.25 Hz during more than one year with few short breaks. Prolongation of intervention free period of LIS operation up to 3 months was achieved by using of CO2 laser gas mixture regeneration circuit. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Galectin-3 is a beta-galactoside binding protein involved in multiple biological processes through interactions with complementary glycoconjugates. We analysed the expression and coexpression of galectin-3 and carcinoembryonic antigen (CEA), one of the putative galectin-3 ligands, in medullary thyroid carcinoma (MTC).An immunohistochemical study using monoclonal antibodies was performed on paraffin sections of 20 cases of sporadic MTC comprising 10 cases without and 10 cases with lymph node metastases at the time of surgery. CEA expression was found in all tumours, distributed predominantly in the cytoplasm and occasionally at the cell surface. In the majority of cases (18/20) moderate to strong intensity of staining was found in most of the cells. Positive cytoplasmic staining for galectin-3 was found in 16/20 cases, but varied in intensity and distribution from weak/focal (7/16) to moderate (7/16) or strong (2/16). More intense staining for galectin-3 was mainly associated with MTC cases involving lymph node metastases. Eight out of these 10 cases showed moderate to strong galectin-3 expression concomitant with CEA expression throughout the tumour tissue.These findings suggest that galectin-3 might play a role in the pathobiology of MTC. Simultaneous expression of galectin-3 and CEA in the same tumour cells at an advanced stage of MTC indicates the possibility of their autocrine cooperation during tumour progression.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1063-7834
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Three experiments on the tellurium recrystallization by a modified Bridgman method were performed under microgravity conditions on board the Mir orbital space laboratory using a ChSK-1 Kristallizator furnace. The physical properties of samples were studied, including the final crystal structure, the distribution of impurities and defects, and the charge carrier concentration and mobility. The results were compared to the analogous parameters of crystals remelted using the same method under the normal gravity conditions. It is established that the samples recrystallized in a close volume under the on-board microgravity conditions “break off” from the container walls and touch the walls only in a few points. This circumstance gives rise to special effects, such as the growth of crystals with a free surface and deep supercooling. Study of the distribution of electrically active impurities over the length of ingots shows evidence of the presence of thermocapillary convective flows in the melt under the microgravity conditions. The flows tend to increase upon separation of the melt from the container walls. The contributions due to impurities and electrically active structural defects to the charge carrier distribution are taken into account. The single-crystal sample obtained upon the partial recrystallization of tellurium in a close container volume under the on-board microgravity conditions exhibits the electrical characteristics comparable to those of a crystal grown by the Czochralski technique under the normal gravity conditions.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Measurement techniques 43 (2000), S. 930-934 
    ISSN: 1573-8906
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract The reliability of predictive control of product parameters in the presence of additive and multiplicative measurement errors is evaluated.
    Type of Medium: Electronic Resource
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