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  • 1
    Electronic Resource
    Electronic Resource
    Chemistry of 9-diazoxanthene and 9-xanthylidene (1979)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 101 (1979), S. 3906-3916 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00508a031
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  • 2
    Electronic Resource
    Electronic Resource
    Reinvestigation and reevaluation of addition and insertion reactions of 9-diazoxanthene and 9-xanthylidene (1978)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 100 (1978), S. 2922-2923 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00477a074
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Book reviews (1996)
    Springer
    Mineralium deposita 31 (1996), S. 250-252 
    Details
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00204035
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  • 4
    Electronic Resource
    Electronic Resource
    Male and female meiosis in grasshoppers II. Chorthippus brunneus (1975)
    Springer
    Chromosoma 51 (1975), S. 381-389 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The frequencies and distribution patterns of chiasmata in the autosomal bivalents of Chorthippus brunneus are very similar in male and female meiosis. The mean cell chiasma frequency of oocytes is however significantly higher than that of spermatocytes, but this difference is almost certainly due to the incremental effect of the X bivalent on the chiasma frequencies of oocytes. The implications of these findings in terms of chiasma control are briefly discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326324
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  • 5
    Electronic Resource
    Electronic Resource
    Analysis of exchanges in differentially stained meiotic chromosomes of Locusta migratoria after BrdU-substitution and FPG staining (1978)
    Springer
    Chromosoma 69 (1978), S. 163-178 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Differential staining of the sister-chromatids of meiotic chromosomes of Locusta migratoria was achieved following abdominal implantation of BrdU tablets and fluorescent plus Giemsa (FPG) staining of fixed and squashed testicular follicles. This paper presents a detailed analysis of crossover exchanges between light and dark chromatids in monochiasmate bivalents. Approximately half the bivalents studied had visible exchanges of dark and light chromatids associated with the chiasmata, as expected if chiasmata originate by breakage and rejoining exchange events between randomly selected non-sister chromatids. In all the bivalents studied the visible crossover exchanges coincided exactly with chiasmata thus showing that chiasma movement (terminalisation) does not occur subsequent to crossing-over in Locusta migratoria, and that chiasmata are therefore accurate indicators of crossing over. It was noted that a proportion (9.5%) of chiasmata were associated with apparently anomalous exchanges of dark and light chromatids which could not be explained by conventional crossing-over. Various hypotheses for the origin of these anomalous exchanges are considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00329915
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  • 6
    Electronic Resource
    Electronic Resource
    Adaptive plasticity in the control of locomotor trajectory (1995)
    Springer
    Experimental brain research 102 (1995), S. 540-545 
    Details
    ISSN: 1432-1106
    Keywords: Adaptive plasticity ; Locomotor trajectory ; Foot nystagmus ; Somatosensory-vestibular interactions ; Rotating treadmill
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Eight human subjects were exposed to 2 h of walking on the perimeter of a horizontally rotating disc with the body remaining still in space. After adaptation to this experience subjects were blindfolded and asked to walk straight ahead on firm ground. When doing so all subjects generated curved walking trajectories of radii ranging from 65 to 200 inches and angular velocities from 7 to 20 deg/s. Subsequent trials over the next half hour revealed retained, but decreasing, trajectory curvature. Angular velocities associated with these trajectories were well above vestibular sensory threshold, yet all subjects consistently perceived themselves as walking straight ahead. The blindfolded subjects were also asked to propel themselves in a straight line in a wheel chair. Post-adaptation wheel chair trajectories showed no change from those before adaptation. Hence we infer that it was the relation between somatosensory/ motor elements of gait and the perception of trunk rotation that had been remodelled during walking on the turning disc. This novel form of adaptive plasticity presumably serves to maintain optimal values of central neural parameters that control the trajectory of locomotion. The findings may have significant implications for the diagnosis and rehabilitation of locomotor and vestibular disorders.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00230658
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  • 7
    Electronic Resource
    Electronic Resource
    Motor learning in the “podokinetic” system and its role in spatial orientation during locomotion (1998)
    Springer
    Experimental brain research 120 (1998), S. 377-385 
    Details
    ISSN: 1432-1106
    Keywords: Key words Spatial orientation ; Podokinetic system ; Vestibular system ; Self-motion perception ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The present study characterizes a previously reported adaptive phenomenon in a somatosensory-motor system involved in directional control of locomotor trajectory through foot contact with the floor. We call this the “podokinetic” (PK) system. Podokinetic adaptation was induced in six subjects by stepping in-place over the axis of a horizontally rotating disc over a range of disc angular velocities (11.25–90°/s) and durations (7.5–60 min). After adaptation, subjects were blindfolded and attempted to step in-place on the floor without turning. Instead they all rotated relative to space. The rate of the “podokinetic afterrotation” (PKAR) was linearly related to stimulus amplitude up to 45°/s, and the ratio of initial PKAR velocity to that of the adaptive stimulus was approximately 1:3. PKAR exhibited exponential decay, which was composed of “short-” and “long-term” components with “discharging” time constants on the order of 6–12 min and 1–2 h, respectively. The effect of stimulus duration on PKAR revealed a “charging” time constant that approximated that of the short-term component. A significant suppression of PKAR occurred during the 1st min of the postadaptive response, suggesting functional interaction between the PK and vestibular systems during the period of vestibular stimulation. During PKAR subjects perceived no self-rotation, indicating that perception as well as locomotor control of spatial orientation were remodeled by adaptation of the PK system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002210050411
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  • 8
    Electronic Resource
    Electronic Resource
    The pharmacokinetics of beta-methyl digoxin compared with digoxin tablets and capsules (1976)
    Springer
    European journal of clinical pharmacology 10 (1976), S. 231-236 
    Details
    ISSN: 1432-1041
    Keywords: Digoxin ; beta-methyl-digoxin ; capsules ; bioavailability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The intestinal absorption and urinary elimination rate of total cardioactive material was compared following digoxin and beta-methyldigoxin (BMD) administration to twelve healthy volunteers. Significantly more injected digoxin was recovered in urine. Urinary clearance was more rapid for digoxin, mean half-lives of elimination being 35 hours for digoxin and 40 hours for BMD. Calculated percentage intestinal absorption was lowest for digoxin tablets with a dissolution rate of 77% in one hour, intermediate for BMD tablets, and maximal for an experimental soft gelatin formulation of digoxin in solution. Respective mean values were 75%, 87% and 97%. Similar steady state plasma concentrations followed twice daily ingestion of the 0.25 mg digoxin tablets and 0.20 mg BMD tablets. Mean peak plasma concentration and percentage urinary recovery of ingested dose were higher during continued BMD administration. Between-subject variation in absorption was higher for the digoxin tablets. The comparative intestinal absorption of BMD and digoxin depends upon the formulation. Digoxin is virtually completely absorbed from a solution encapsulated in soft gelatin. Relatively more BMD is eliminated by nonrenal routes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00558334
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  • 9
    Electronic Resource
    Electronic Resource
    The BEAN experiment - An EISCAT study of ion temperature anisotropies (1995)
    Springer
    Annales geophysicae 13 (1995), S. 177-188 
    Details
    ISSN: 0992-7689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Results are presented from a novel EISCAT special programme, SP-UK-BEAN, intended for the direct measurement of the ion temperature anisotropy during ion frictional heating events in the high-latitude F-region. The experiment employs a geometry which provides three simultaneous estimates of the ion temperature in a single F-region observing volume at a range of aspect angles from 0° to 36°. In contrast to most previous EISCAT experiments to study ion temperature anisotropies, field-aligned observations are made using the Sodankylä radar, while the Kiruna radar measures at an aspect angle of the order of 30°. Anisotropic effects can thus be studied within a small common volume whose size and altitude range is limited by the radar beamwidth, rather than in volumes which overlap but cover different altitudes. The derivation of line-of-sight ion temperature is made more complex by the presence of an unknown percentage of atomic and molecular ions at the observing altitude and the possibility of non-Maxwellian distortion of the ion thermal velocity distribution. The first problem has been partly accounted for by insisting that a constant value of electron temperature be maintained. This enables an estimate of the ion composition to be made, and facilitates the derivation of more realistic line-of-sight ion temperatures and temperature anisotropies. The latter problem has been addressed by assuming that the thermal velocity distribution remains bi-Maxwellian. The limitations of these approaches are discussed. The ion temperature anisotropies and temperature partition coefficients during two ion heating events give values intermediate between those expected for atomic and for molecular species. This result is consistent with an analysis which indicates that significant proportions of molecular ions (up to 50%) were present at the times of greatest heating.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00585-995-0177-x
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  • 10
    Electronic Resource
    Electronic Resource
    A comparison of EISCAT and Dynasonde measurements of the auroral ionosphere (1997)
    Springer
    Annales geophysicae 14 (1997), S. 1403-1412 
    Details
    ISSN: 0992-7689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Incoherent-scatter radar and ionospheric sounding are powerful and complementary techniques in the study of the Earth’s ionosphere. The work presented here involves the use of the Tromsø Dynasonde as a correlative diagnostic with the EISCAT incoherent-scatter radar. A comparison of electron-density profiles shows how a Dynasonde can be used to calibrate an incoherent-scatter radar and to monitor changes in the system. Sky-maps of the direction of Dynasonde echoes are compared with EISCAT-derived density profiles to illustrate how a Dynasonde can be used to measure the drift velocity of auroral features. Vector velocities fitted to Dynasonde echoes are compared with EISCAT-derived plasma velocities. The results show good agreement when the data are taken during quiet to moderately active conditions and averaged over time scales of 30 min or more.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00585-996-1403-x
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