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  • 1
    Electronic Resource
    Electronic Resource
    Differential ontogenic pattern of metabotropic [3H]-l-glutamate receptors in normal and granule cell-deficient mouse cerebellum (1996)
    Springer
    Experimental brain research 107 (1996), S. 361-366 
    Details
    ISSN: 1432-1106
    Keywords: Metabotropic glutamate receptors ; Cerebellar ontogeny ; Methylazoxymethanol ; Mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract [3H]-l-glutamate binding site distribution corresponding to metabotropic receptors was studied by autoradiography during normal and altered cerebellar ontogeny in mice treated on postnatal days (PND) 5 and 6 with the antimitotic methylazoxy-methanol (MAM). Quisqualate (QA)-induced and (2S, 3S, 4S)-α-(carboxycyclopropyl)-glycine (L-CCG-I)-induced [3H]-l-glutamate binding inhibition allowed us to distinguish between group I and group II metabotropic receptor binding sites. In control cerebellar cortex, the QA-sensitive binding site density increases during development, while the L-CCG-I-sensitive binding site density decreases. In the deep cerebellar nuclei (DCN), both populations of binding sites decrease during ontogeny. The antimitotic treatment induces: (1) a slight but significant increase in the QA-sensitive binding sites in the DCN at PND 10 and in the cerebellar cortex beginning from PND 20; (2) a retarded decrease in the L-CCG-I-sensitive metabotropic receptor binding site density. These differences could be due to a retarded cell maturation and/or an over-expression of some postsynaptic receptors in the adult cerebellum in response to the afference deficiency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00230418
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  • 2
    Electronic Resource
    Electronic Resource
    Negative remanence in exchange coupled Co/Rh/Co sandwich structures: Experiment and model (abstract) : The 41st annual conference on magnetism and magnetic materials (1997)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 81 (1997), S. 3914-3914 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: It is shown within a simple micromagnetic model calculation that novel magnetic hysteresis behavior including the unusual phenomenon of negative remanence can occur in asymmetric exchange coupled bi- and multilayer films. The latter denotes a magnetization state opposite to the field direction in which the sample was premagnetized. We have observed such effects in polar Kerr hysteresis measurements from perpendicularly oriented sandwich structures grown on Pt(111) buffers, e.g., Co(0.8 nm)/Rh(0.9 nm)/Co(0.8 nm). The model minimizes the total magnetic energy as function of the applied field and angles phi1 and phi2 of the two layers with respect to the film normal (easy) direction. The energy includes besides external field energy, a demagnetization term and interlayer exchange and anisotropy contributions. The general shape of the experimentally observed hysteresis loops can be reproduced, if one assumes slight asymmetries in the magnetic properties of the ferromagnetic layers. These could be caused by unequal thicknesses and/or local roughnesses which would alter the interfacial anisotropy contributions. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.365069
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  • 3
    Electronic Resource
    Electronic Resource
    Investigation of silicon field-effect transistors in cryogenic amplifiers for radio frequency superconducting quantum interference devices (1995)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 3296-3299 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We have prepared n-channel silicon field-effect transistors, which are capable of working at liquid helium temperatures (4.2 K) and used them in cooled preamplifiers for rf superconducting quantum interference device (SQUID) readout electronics. All metallizations of these transistors were made of niobium, to study the possibility of a further integration of a SQUID and FET on the same chip. Using the FETs in a cooled preamplifier together with a rf SQUID gradiometer, the flux noise of the system could be reduced by a factor of 3 compared to a room temperature low noise preamplifier. We have also performed calculations of a possible increase of the substrate temperature due to the power dissipation of the FET and have measured the cross talk between FET and SQUID. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1145497
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  • 4
    Electronic Resource
    Electronic Resource
    One-week triple therapy with omeprazole, amoxycillin and either clarithromycin or metronidazole for cure of Helicobacter pylori infection (1996)
    Oxford BSL : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 10 (1996), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aim: The present study was designed to evaluate the efficacy and tolerability of 1-week triple therapy regimens for Helicobacter pylori. Methods: In two consecutive series, 120 patients with proven H. pylori infection and peptic ulcer disease or functional dyspepsia were treated with either omeprazole 20 mg b.d., amoxycillin 1 g b.d. and clarithromycin 250 mg b.d. (OAC; n=60) or with omeprazole 20 mg b.d., amoxycillin 1 g b.d. and metronidazole 400 mg b.d. over 1 week (OAM; n=60). H. pylori infection was assessed by rapid urease test, culture and histology before and 4 weeks after cessation of the eradication therapy. Results: H. pylori eradication succeeded in 53 out of 60 patients by omeprazole–amoxycillin–clarithromycin (OAC) (88%; 95% CI 77–95%) and in 47 out of 60 patients by omeprazole–amoxycillin–metronidazole (OAM) (78%; 95% CI 66–88%) (P=0.22). Nine patients of each group available for follow-up reported adverse events (15.0 and 15.5%, respectively) without necessity of discontinuation of the study medications. Serious adverse events were not observed. Conclusions: Simple and convenient 1-week triple therapies consisting of omeprazole, amoxycillin and either clarithromycin or metronidazole are sufficiently effective in eradicating H. pylori infection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.1996.727119000.x
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  • 5
    Electronic Resource
    Electronic Resource
    fac-Aqua[1,2-bis(diphenylphosphino)ethane-P,P']tricarbonylmanganese tetrafluoroborate (monoclinic form) (1999)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 55 (1999), S. 0-0 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S010827019909856X
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  • 6
    Electronic Resource
    Electronic Resource
    Some methodological issues in neuroradiological research in psychiatry (1995)
    Springer
    Journal of neural transmission 99 (1995), S. 7-54 
    Details
    ISSN: 1435-1463
    Keywords: Computed tomography (CT) ; functional magnetic resonance imaging (fMRI) ; late-onset depression ; late-onset paranoid disorder ; magnetic resonance imaging (MRI) ; magnetic resonance spectroscopy (MRS) ; normal pressure hydrocephalus (NPH) ; primary degenerative dementia ; psychiatry ; ultrasound ; vascular dementia ; white matter hyperintensities
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An outline is given of some of the methodological issues discussed in neuroradiological research on psychiatric illness. Strengths and shortcomings of magnetic resonance imaging (MRI) in depicting and quantifying brain structures are described. Temporal lobe anatomy and pathology are easily accessible to MRI, whereas limits on anatomical delineation hamper approaches to frontal lobe study. White matter hyperintense lesions are sensitively depicted by MRI, but specificity is limited. Distinction of vascular and primary degenerative dementia is considerably improved by CT and MRI analysis. Computed tomography (CT) and MRI have enhanced the understanding of treatable organic psychiatric disorders, e.g., normal pressure hydrocephalus. Subcortical and white matter pathology has been replicated in CT and MRI studies of late-onset psychiatric disorders, clinical overlap with cerebrovascular disease or neurodegeneration may be of import. Transcranial sonography findings of brainstem structural change specific to unipolar depression may contribute to the understanding of affective psychoses. Magnetic resonance spectroscopy and functional MRI are likely to stimulate psychiatric research in the future.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01271468
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  • 7
    Electronic Resource
    Electronic Resource
    Disturbances of cerebrospinal fluid (CSF) circulation—neuropsychiatrie symptoms and neuroradiological contribution (1995)
    Springer
    Journal of neural transmission 99 (1995), S. 79-88 
    Details
    ISSN: 1435-1463
    Keywords: Communicating hydrocephalus ; aqueductal stenosis ; normal-pressure hydrocephalus ; corpus callosum ; third ventricle ; dementia ; organic brain syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The present study aimed at relating dementia, pseudo-neurasthenic and affective organic brain syndromes to underlying type of CSF flow disorder and to subsequent alteration of anatomy. T2*-weighted magnetic resonance imaging (MRI) in the midsagittal plane permitted an analysis of aqueductal CSF flow phenomena and hydrocephalus-induced elevation, thinning and dorsal impingement of the corpus callosum. Furthermore, the width of the third ventricle was measured on the transverse scout images. 72 patients with communicating hydrocephalus (increased aqueductal CSF pulsations) and 26 patients with aqueductal stenosis (absence of aqueductal flow phenomena) were compared with 22 controls. Dementia and affective disorders were distributed equally among both CSF flow subgroups whereas pseudo-neurasthenic syndromes were observed more frequently in non-communicating hydrocephalus (p 〈 0.03). Alzheimer-type and multiinfarct dementia syndromes were found more frequently in communicating hydrocephalus whereas non-classifiable dementia showed some predilection for non-communicating hydrocephalus. Callosal height, area and third ventricular width did not predict affective or pseudoneurasthenic disorder whereas third ventricular width (p 〈 0.01) and callosal area (p 〈 0.05) discriminated between demented and non-demented patients. Dorsal impingement of the corpus callosum by the falx was a non-specific finding.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01271471
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  • 8
    Electronic Resource
    Electronic Resource
    Ventricular abnormality in patients with postpartum psychoses (1998)
    Springer
    Archives of women's mental health 1 (1998), S. 45-47 
    Details
    ISSN: 1435-1102
    Keywords: Keywords: Postpartum psychoses; cycloid psychoses; cerebral computered tomography; ventricular abnormalities.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Ventricular and cisternal CSF spaces were quantified in 14 women 12 of whom had cycloid psychoses with postpartum onset. When compared to age-matched female patients with cycloid psychoses or bipolar affective disorders outside the puerperium and neurological controls left ventricular area, planimetric VBR, and superior cerebellar cistern volume were significantly larger in the postpartum psychosis group. This finding could reflect an unspecific brain structural vulnerability marker in some patients with psychoses of the puerperium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007370050005
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  • 9
    Electronic Resource
    Electronic Resource
    Dynamics of a stochastically driven running sandpile (1995)
    Springer
    Journal of nonlinear science 5 (1995), S. 167-188 
    Details
    ISSN: 1432-1467
    Keywords: self-organized criticality ; stochastic processes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Summary We analyze in detail a one-dimensional sandpile with spatially stochastic driving at a finite rate. The dynamics shows three different phases, depending on the on-site relaxation rate and the stochastic driving rate. Two phases are characterized by the presence of traveling waves. The third phase shows algebraic relaxation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01208378
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  • 10
    Electronic Resource
    Electronic Resource
    The corpus callosum in communicating and noncommunicating hydrocephalus (1995)
    Springer
    Neuroradiology 37 (1995), S. 212-218 
    Details
    ISSN: 1432-1920
    Keywords: Key words Corpus callosum ; Hydrocephalus ; Dementia ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To investigate morphological changes in the corpus callosum in hydrocephalus and to correlate them with clinical findings we studied sagittal T2*-weighted cine MR images of 163 patients with hydrocephalus. The height, length and cross-sectional area of the corpus callosum were measured and related to the type of cerebrospinal fluid flow anomaly and to clinical features, especially dementia. With expansion of the lateral ventricles the corpus callosum showed mainly elevation of its body and, to a lesser degree, increase in length. Upward bowing was more pronounced in noncommunicating than in communicating hydrocephalus. Dorsal impingement on the corpus callosum by the free edge of the falx correlated with the height of the corpus callosum. Cross-sectional area did not correlate with either height, length or impingement; it was, however, the strongest anatomical discriminator between demented and nondemented patients. The area of the corpus callosum was significantly smaller in patients with white matter disease. Our findings suggest that, due to its plasticity, the corpus callosum can to some degree resist distortion in hydrocephalus. Dementia, although statistically related to atrophy of the corpus callosum, is possibly more directly related to white matter disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01578260
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