Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1995-1999  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 44 (1995), S. 222-226 
    ISSN: 1420-908X
    Keywords: Immunity ; Type II collagen ; Proteoglycan ; Osteoarthritis ; Mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We measured immunity to type II collagen and proteoglycans in osteoarthritic C57BL mice to determine whether it is related to osteoarthritis pathogenesis. Histological examination revealed articular cartilage lesions in all mice and synovitis in only a few mice. Immunological responses to type II collagen were found in collagen arthritic mice, but not in C57BL mice. Furthermore, immunological responses to proteoglycans were observed in proteoglycan-immunized mice, but not in C57BL mice. Therefore, articular cartilage degeneration may not result in autoimmunity to type II collagen and proteoglycans in osteoarthritis of C57BL mice, and immune responses to these components may not be a primary etiology of osteoarthritis in this model.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 44 (1995), S. 79-82 
    ISSN: 1420-908X
    Keywords: Collagen ; Arthritis ; Cyclosporin and hyaluronan
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Serum hyaluronan (HA) levels were measured in a rat model of collagen arthritis using a sandwich enzyme-linked immunosorbent assay. Values became elevated as the arthritis developed, correlating with its severity. Daily subcutaneous treatment with cyclosporin at the dose of 25 mg/kg per day for fourteen days completely prevented anti-type II collagen antibody production and the serum HA increase as well as development of collagen arthritis. HA in the blood may thus provide a good quantitative marker for joint disease in rat collagen arthritis with potential as a tool for evaluation of drug efficacy in this experimental model.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International orthopaedics 20 (1997), S. 346-349 
    ISSN: 1432-5195
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé. Dix patients avec un cal vicieux en rotation du fémur ou du tibia ont fait l’objet d’une correction par une ostéotomie intramédullaire à foyer fermé. Il y avait 9 hommes et une femme. L’âge moyen est compris entre 18 et 56 ans. Huit patients présentaient un cal en rotation externe du fémur et les deux autres avaient un tibia déformé. Le cal vicieux en rotation variait de 30 à 60 degrés et était associéà un raccourcissement de 15 à 30 mm dans 6 cas. Toutes les ostéotomies de dérotation ont été réalisées par section intramédullaire et fixées par clou verrouillé. Le raccourcissement a été corrigé dans le même temps opératoire. Le plus récent contrôle des patients montre que la déformation résiduelle est moins que 5 degrés et le raccourcissement de moins de 15 mm. Tous les patients étaient satisfaits de la longueur et la mobilité du membre inférieur opéré. Il n’y eut aucune complication per- ou postopératoire sauf un retard de consolidation. Dans ce dernier cas, la consolidation fut obtenue à 2 ans sans intervention supplémentaire. L’ostéotomie intramédullaire est la fa*on la plus sûre d’obtenir la correction d’un cal vicieux rotatoire d’un os long, avec un taux de complication minimal.
    Notes: Summary. Ten patients with rotational deformities after fractures of the femur or tibia were treated by closed intramedullary osteotomy. Eight had an external rotation deformity of the femur and 2 had deformities of the tibia. The rotational deformity varied from 30° to 60° and 6 patients had shortening of 15 mm to 30 mm. The osteotomies were carried out with an intramedullary saw and were fixed by an interlocking nailing. Shortening was corrected at the same time. At follow up the average rotational deformity was less than 5° and shortening less than 15 mm. All the patients felt that they had a normal range of movement and equal length. There were no complications, except for one case of delayed union in which consolidation occurred at 24 months without any further procedures.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...