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  • 1
    Electronic Resource
    Electronic Resource
    The volume of Purkinje cells decreases in the cerebellum of acrylamide – intoxicated rats, but no cells are lost (1994)
    Springer
    Acta neuropathologica 88 (1994), S. 307-312 
    Details
    ISSN: 1432-0533
    Keywords: Key words Acrylamide ; Cerebellum ; Neuronal volume ; Neuronal number ; Stereology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of acrylamide intoxication on the numbers of granule and Purkinje cells and the volume of Purkinje cell perikarya have been evaluated with stereological methods. The analysis was carried out in the cerebella of rats that had received a dose of 33.3 mg/kg acrylamide, twice a week, for 7.5 weeks. The total numbers of cerebellar granule and Purkinje cells were estimated using the optical fractionator and the mean volume of the Purkinje cell perikarya was estimated with the vertical rotator technique. The volumes of the molecular layer, the granular cell layer and the white matter were estimated using the Cavalieri principle. The mean weight of the cerebellum of the intoxicated rats was 7   % lower than that of the controls rats (2P = 0.001). The numbers of the Purkinje cells and granule cells were the same in both groups, but the mean volume of the perikarya of the Purkinje cells in the intoxicated rats was 10.5   % less than that of the control group (2P = 0.004). The volume of the granular cell layer was reduced by 15   % (2P = 0.006) but there were no differences in the volumes of the molecular layer and the white matter in the intoxicated and control animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00310374
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  • 2
    Electronic Resource
    Electronic Resource
    Demineralization effects on the EPR properties of Argonne premium coals (1991)
    s.l. : American Chemical Society
    Energy & fuels 5 (1991), S. 561-568 
    Details
    ISSN: 1520-5029
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ef00028a006
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  • 3
    Electronic Resource
    Electronic Resource
    Moisture determination and structure investigation of native and dried Argonne premium coals. A hydrogen-1 solid-state NMR relaxation study (1992)
    s.l. : American Chemical Society
    Energy & fuels 6 (1992), S. 651-655 
    Details
    ISSN: 1520-5029
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ef00035a017
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  • 4
    Electronic Resource
    Electronic Resource
    Evidence for the formation of stable coal-N-methylpyrrolidinone and coal-pyridine gels (1993)
    s.l. : American Chemical Society
    Energy & fuels 7 (1993), S. 47-51 
    Details
    ISSN: 1520-5029
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ef00037a009
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  • 5
    Electronic Resource
    Electronic Resource
    Copepod nutritional condition and pelagic production during autumn in Kosterfjorden, western Sweden (1990)
    Springer
    Marine biology 104 (1990), S. 197-208 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The in situ grazing rate and nutritional condition of copepods were studied during October/November 1985, by analyzing gut fluorescence (feeding), body size and lipid composition (nutritional state), and electron transport system (ETS) activity (respiration rate) of copepods from surface-and deep-water in Kosterfjorden on the Swedish west coast. These parameters were related to the physical and biological environment, as defined by light, hydrography, autotrophic and bacterial production and seston in the water column. The results show a gradual build-up of the autumn phytoplankton bloom in the uppermost meters, with a peak in total autotrophic production in mid October of ca 550 mg C m−2 d−1, and a bacterial net production corresponding to 15% of this. Phytoplankton exudates made up, on average, 47% of the primary production and more than 50% of this was utilized by the bacteria. Copepods occurring in the surface-water exhibited grazing rates corresponding to between 11 and 18% of their body C d−1 and potential growth rates of 0 to 9% d−1. Copepod populations in the surface water were composed of individuals with higher average body-weight and lower lipid-proportion than those from the deep-water.Calanus finmarchicus in the deep-water showed characters indicating diapause condition, while this was not observed forAcartia clausi. Differences in lipid content and composition indicate thatC. finmarchicus, Pseudocalanus sp. andA. clausi represent three successive points on a scale of tolerance for fluctuations in the food environment. Adult femaleMetridia longa was the only one among seven species/stages of copepods in the deep-water (≥ 50 m depth) that contained phytoplankton pigments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01313259
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  • 6
    Electronic Resource
    Electronic Resource
    Cystic fibrosis screening in neonates – measurement of immunoreactive trypsin and direct genotype analysis for ΔF508 mutation (1994)
    Springer
    European journal of pediatrics 153 (1994), S. 569-573 
    Details
    ISSN: 1432-1076
    Keywords: Key words     Cystic fibrosis ; Screening ; Infant ; Trypsin ; Mutation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract      This study investigated the clinical usefulness of screening for cystic fibrosis (CF) in 19992 newborns, over 39 months, in an Austrian population. Immunoreactive serum trypsin (IRT) determination was followed by sweat chloride analysis (sweat test) to establish diagnosis. In a retrospective analy- sis covering 6 months of the study period, individuals who were con- sidered to be at risk after IRT estimation (n = 22) were analysed for DF508 mutation, using a new method of DNA extraction from the initial dried blood specimens. A total of 119 infants (0.6%) had values greater than 750 ng trypsin/ml whole blood. In 88 babies sweat tests were performed, leading to the diagnosis of CF in 11 cases. One patient was not initially identified by screening but was later discovered due to his clinical status. Three infants were noted to carry the ΔF508 mutation (1 homozygous, 2 heterozygous). Two of these babies already had CF. The second heterozygote was a carrier. A highly efficient three tier screening strategy is presented in which IRT estimation, determination of ΔF508 status and sweat chloride testing could lead to a high sensitiv- ity analysis of this population.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050192
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  • 7
    Electronic Resource
    Electronic Resource
    Cystic fibrosis screening in neonates — measurement of immunoreactive trypsin and direct genotype analysis for ΔF508 mutation (1994)
    Springer
    European journal of pediatrics 153 (1994), S. 569-573 
    Details
    ISSN: 1432-1076
    Keywords: Cystic fibrosis Screening ; Infant ; Trypsin Mutation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study investigated the clinical usefulness of screening for cystic fibrosis (CF) in 19992 newborns, over 39 months, in an Austrian population. Immunoreactive serum trypsin (IRT) determination was followed by sweat chloride analysis (sweat test) to establish diagnosis. In a retrospective analysis covering 6 months of the study period, individuals who were considered to be at risk after IRT estimation (n = 22) were analysed for ΔF508 mutation, using a new method of DNA extraction from the initial dried blood specimens. A total of 119 infants (0.6%) had values greater than 750mg trypsin/ml whole blood. In 88 babies sweat tests were performed, leading to the diagnosis of CF in 11 cases. One patient was not initially identified by screening but was later discovered due to his clinical status. Three infants were noted to carry the ΔF508 mutation (1 homozygous, 2 heterozygous). Two of these babies already had CF. The second heterozygote was a carrier. A highly efficient three tier screening strategy is presented in which IRT estimation, determination of ΔF508 status and sweat chloride testing could lead to a high sensitivity analysis of this population.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02190660
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  • 8
    Electronic Resource
    Electronic Resource
    Dynamic aspects of expanding cava septi pellucidi et Vergae (1990)
    Springer
    Acta neurochirurgica 104 (1990), S. 147-150 
    Details
    ISSN: 0942-0940
    Keywords: Cavum Vergae ; cavum septi pellucidi ; cerebral cysts ; cerebral ventricles ; hydrocephalus ; shunt ; stereotactic techniques
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two paediatric patients with expanding cysts of the cava Vergae et septi pellucidi are presented. In the first patient, consecutive CT scans showed agrowing cavum thought to be responsible for his dramatic increase in head circumference. In the other patient, the expanding cavum was discovered because a routine skull X-ray after minor head trauma revealed marked impressiones digitatae. Both patients were successfully treated with stereotactically placed internal shunts from the cysts via the lateral ventricle to the subarachnoid space. During this procedure, contrast medium was instilled, and the cysts were visualized on postoperative CT scans. Some dynamic aspects of such expanding cava are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01842833
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  • 9
    Electronic Resource
    Electronic Resource
    On the electrical conductivity of the mid-mantle: II. Delineation of heterogeneity by application of extremal inverse solutions (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 101 (1990), S. 0 
    Details
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Long-period equivalent scalar magnetotelluric impedance functions from 22 magnetic observatories distributed over the Earth's surface are inverted to test the hypothesis that there exists significant lateral heterogeneity in the electrical conductivity structure of the mid-mantle. Limited spaces of extremal models are examined, and strict bounds are placed on the range of permissible models. Joint D+ inversion of combined response functions from observatory pairs proves the requirement for global heterogeneity, while exploration of H+ layered-earth model space suggests systematic regional heterogeneity, indicating that enhanced upper mantle conductivity is found within the Pacific basin and Baikal Rift zone and is absent elsewhere. The results of these extremal inverse solutions are compared with the Backus–Gilbert-like Schmucker inversion and a heuristic inversion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-246X.1990.tb05571.x
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  • 10
    Electronic Resource
    Electronic Resource
    Aeromonas salmonicida subsp. salmonicida: correlation of protein patterns, antibiotic resistance, exoprotease activity, haemolysis and pathological lesions produced in vivo (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 17 (1994), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. A collection of 130 strains of the bacterial fish pathogen Aeromonas salmonicida subsp. salmonicida isolated from diseased salmonids in Denmark, Norway, North America and Scotland has been characterized with regard to protein patterns, antibiotic resistance and exoprotease activity. Whole cell and outer membrane protein profiling could distinguish three different profiles in A. salmonicida. Eight outer membrane proteins were demonstrated (49, 40, 38, 37, 33, 31, 30 and 29 kDa). One protein profile was deficient in a 38 kDa outer membrane protein and instead contained an outer membrane protein of 37 kDa which was not detectable among the other protein profiles. Strains with the 37 kDa outer membrane protein showed multiple low-level antibiotic resistance towards cephalothin, penicillin, chloramp-henicol, tetracycline and quinolones. In addition, these strains were exoprotease deficient. Strains with the 37 kDa protein were unable to degrade cattle and trout serum proteins and displayed a delayed degradation of casein. Haemolysis on cattle blood agar plates was similarly delayed. In vivo examination of extracellular products from a normal protein profile strain and one with the 37 kDa outer membrane protein demonstrated major differences in pathological effects in rainbow trout. The strain possessing the 37 kDa outer membrane protein produced almost no pathological effects while the normal protein profile strain produced typical furuncles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1994.tb00234.x
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