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  • Articles: DFG German National Licenses  (25)
  • 1985-1989  (25)
  • 1
    ISSN: 0942-0940
    Keywords: Glucocorticoid receptor ; brain tumour ; malignant astrocytomas ; steroid treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Glucocorticoid receptors were measured in tissue samples from 12 patients with glioblastoma multiforme. The receptor was found in all patients. The concentration of glucocorticoid receptor was found to be high in the periphery of the tumour, low in the surrounding brain tissue and low in the central part of the tumour in 6 of the patients. The possible role of the glucocorticoid receptor distribution in relation to growth regulation is discussed. A decreasing receptor concentration found at reoperation in two patients indicates a possible antineoplastic effect of high dose methylprednisolone pulse therapy on glucocorticoid receptor positive glioblastomas.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0942-0940
    Keywords: Epidural pressure ; intraventricular pressure ; pressure monitoring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The Plastimed® epidural pressure sensor was evaluated in 35 patients, twenty-eight of whom were suffering from head injury. In seven patients simultaneous intraventricular pressure measurements were obtained. The epidural pressure sensor was only functioning satisfactorily in approximately 2/3 of the patients, while it was malfunctioning or not functioning in the remainder. In seven comparable IVP/EDP studies significant differences up to 25 mm Hg were noted. In three patients IVP was greater than EDP. In two patients the opposite was true. No significant complications were observed. These unsatisfactory results have made us abandon the technique and resort to intraventricular or subarachnoidal pressure measurements.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 15 (1988), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The single case experimental design was used to study day-to-day variations in the onset (PL), tolerance (PT), and intensity (VAS) of masseter muscle pain. Pain was induced by maximum voluntary teeth clenching, with no artificial feedback-control of the level of isometric activity, and static work efforts were quantified by cumulative electromyography. A continual effort to produce maximum static work, about 40% increase from baseline work, elicited in 30–40s an initial sensation of muscular pain that had an intensity of about 25% of maximum possible score. A further increase in maximum static work effort, about 60% increase from baseline work, caused in about 2min an intolerable increase in the intensity of muscular pain, about 50% of maximum possible score. Whereas PL showed day-to-day variation, PT and the ratio PL:PT did not. Intensity (VAS) scores and maximum static work efforts showed no day-to-day variations. Onset (PL) and tolerance (PT) showed no linear associations with VAS scores, and VAS scores showed no linear associations with maximum static work efforts; if anything, the latter associations tended to resemble a cubic parabola. Two different central neural processes, not associated with maximum static work efforts in a simple linear manner, might have been instrumental in: (i) the establishment of criteria for onset and tolerance of pain, and (ii) the discrimination of variable levels of pain intensity.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 15 (1988), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Fifty dentate maxillary casts, obtained from thirty-four males and sixteen females, were mounted in the three-dimensional co-ordinate system of a contour meter. A transverse line of reference (x-axis) was drawn through the distal contact points of the maxillary canines, at a right angle to the y-axis which passed through the contact points of the maxillary central incisors. Relative to the canine-to-canine baseline, the locations of the lateral borders of the right and left first primary rugae were determined. The rugae were distributed on both the anterior and posterior sides of the baseline, and the anterior and posterior distances from the baseline were on the average about 1 mm. The age of the subjects, ranging from 12 to 52 years, appeared to be unrelated to the frequencies of anteriorly and posteriorly positioned rugae. Right and left first primary rugae, located on the anterior side of the baseline, showed a minute asymmetry in their topography. By contrast, there was topographical symmetry when the rugae were located on the posterior side of the baseline.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 12 (1985), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Ten subjects performed deliberate right and left-sided chewing of gum, each exercise with a duration of 60 s, followed by maximum voluntary teeth clenching (MVC) until onset of pains in the masseter muscles (pain threshold). Contractile activities of the right and left masseter muscles were assessed by integrated and cumulative surface electromyography (EMG). When the right and left muscles functioned as chewing side muscles only, they generated practically identical levels of chewing force; the same applied when they functioned as non-chewing side muscles only. During identical functions, EMGs suggested identical motor unit recruitment and firing patterns in the two paired muscles; i.e., units producing relatively high tensions for chewing side activity, and other units producing relatively low tensions for non-chewing side activity. During isometric MVC activity, until onset of pains, the right and left muscles generated practically identical levels of bite force, but right and left motor unit activity patterns seemed to differ. Right and left motor units might have fired at different rates or begun to drop out at different times. In the latter case, rapidly before slowly fatigued units. There was a tendency for a low pain threshold with high chewing side activity in both masseter muscles. Motor units producing high levels of tension, but easily fatigued, might have caused early onset of muscle pains. No relationships could be established between preferred chewing side and side of initial muscle pains, nor between MVC activity and side of pain onset and preferred chewing side.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 13 (1986), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An overview is presented of the physiology and so-called pathophysiology of static muscle contractions in the intact living organism. Static muscle activity produces no external mechanophysical work, but is used for fixation. Contingent upon the levels of the generated forces, and the duration of the isometric contractions, static activities give rise to fatigue and pains. The discomforts are viewed as somatic responses that are normally within physiological limits. That is, upon cessation of isometric contractions there is usually rapid recovery from the discomforts, and they do not normally induce chronic lesions.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 12 (1985), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Three human subjects performed teeth clenching at maximum voluntary contraction strength (MVC) of the mandibular elevator muscles. At intervals of 10 s, ten successive bouts of MVC clenching were exercised until total exhaustion of the contracting muscles (isometric endurance). Isometric endurance time decreased exponentially from 59 to 12 s. The curve of the decrease showed a monotone power function (y=x−1). Electromyographic recordings from masseter muscles suggested that fatigable motor units, possibly fast glycolytic units, dropped out during the initial stages of maintained MVC isometric activity. The silent period of the monosynaptic jaw jerk reflex was increased by about 35% following exhaustion of the masseter muscle.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 12 (1985), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To study lateral bolus placement during mastication, referred to as masticatory lateral preference, fifteen males and ten females chewed sugarless gum for 15, 20 and 25 s, and visual inspections were done of either right or left side bolus placements. In each of three series of observations, there were no significant differences between right or left side bolus placements. Three consecutive spot checks, in single subjects, showed that lateral preference occurred at random. However, information on a favoured chewing side predicted fairly reliably the side of observed masticatory lateral preference. Observed lateral preference could not be predicted from hand laterality. Consistent and predominant right or left lateral preference was, presumably, an expression of mainly motivational chewing behaviour.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 13 (1986), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An overview is presented of the physiology and pathophysiology of dynamic skeletal muscle contractions in the intact living organism. Dynamic muscle activities are divided into concentric contractions with shortening of muscle fibres and the production of positive work, and eccentric contractions with lengthening of muscle fibres and the production of negative work. In positive work, muscle tension overcomes external forces. In negative work, external forces overcome muscle tension. The latter phenomenon, with relatively few active motor units, explains the injuries induced by eccentric contractions. Both the contractile and non-contractile elements are involved in the muscle injuries and, clinically, they are referred to as myofibrositis.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 12 (1985), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To study concurrence of specific electromyographic chewing patterns and the side of mastication, twelve subjects chewed gum for 15, 20 and 25 s. Gum bolus placement on the right or left side of the dentition was estimated by three series of visual inspections. Contraction patterns of the chewing and non-chewing side masseter muscles were appraised by integrated and cumulative surface electromy-ography. Consistent and predominant gum bolus placement on the right side of the dentition could be predicted fairly reliably from comparative electromyographic observations. This was also the case in instances of consistent left-sided gum bolus placement, but not in predominant left-sided bolus placement. The latter phenomenon was explained by deviant observations made in two subjects only. Agreement between a presumed chewing side and a predictive contractility pattern was established in 78% of observations (P〉0-001).
    Type of Medium: Electronic Resource
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