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  • 2005-2009  (2)
  • 1985-1989  (3)
  • 1980-1984  (2)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Journal of molecular medicine 67 (1989), S. 583-587 
    ISSN: 1432-1440
    Schlagwort(e): Insulin infusion pump ; Implantation ; CSII ; Intravenous, intraperitoneal insulin infusion
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Five type I diabetic patients were followed prospectively during treatment with continuous subcutaneous insulin infusion by externally worn pumps and during the first 12 months after implantation of a remote-controlled insulin infusion device (ID1, Siemens AG). Stabilized insulin (Hoe 21 GH, Hoechst AG) was infused intravenously in two and intraperitoneally in three patients. Total observation time was 47.2 patient-months after implantation. Two devices had to be explanted prematurely, one because of a technical failure after 101 days, one due to a skin necrosis over the implant after 236 days. HbA1, frequency of hypoglycemia, total insulin dose, and basal rate infusion did not change after implantation. There was a reduction in the insulin antibodies 6 months after start of intravenous or intraperitoneal insulin delivery. Fasting plasma free insulin levels could be normalized only by intraperitoneal insulin infusion. Although a technical and a surgical problem was observed, our data show the successful implantation and clinical use of programmable dosing devices and stabilized insulin.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Cancer chemotherapy and pharmacology 18 (1986), S. 83-85 
    ISSN: 1432-0843
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Adriamycin-resistant cell lines of the sarcoma 180 of mouse reveal, besides the known resistance mechanism, a decrease in cellular autolysis compared with the original line. This decrease has been demonstrated by comparative analysis of cell-free supernatants isolated from 7-day-old sensitive and resistant ascites tumors in mice. In order to demonstrate these changes we isolated and quantified the DNA, detecting higher amounts within the supernatants of resistant lines. Furthermore, unspecific DNA-cleaving activity within raw homogenates of the cells is substantially lower in the resistant lines. Residual parts of chromatin may trap the drug and in this way lower its effective concentration. However, the results may also reflect changes in enzymatic complement playing a hitherto unknown role within living cells.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 524-525 (Sept. 2006), p. 211-216 
    ISSN: 1662-9752
    Quelle: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Thema: Maschinenbau
    Notizen: In response to the development of new materials and the application of materials andcomponents in new technologies the direct measurement, calculation and evaluation of textures andresidual stresses has gained worldwide significance in recent years. Non-destructive analysis forphase specific residual stresses and textures is only possible by means of diffraction methods. Inorder to cater for the development of these analytical techniques the new Materials ScienceDiffractometer STRESS-SPEC at FRM-II is designed to be equally applied to texture and residualstress analyses by virtue of its flexible configuration. The system compromises a highly flexiblemonochromator setup using three different monochromators: Ge (511), bent silicon (400) andpyrolitic graphite (PG). This range of monochromators and the possibility to vary the take-off anglesfrom 2θM = 35º to 110º allows wavelength adjustment such that measurements can be performedaround a scattering angle of 2θS ~ 90º. This is important in order to optimise neutron flux andresolution, especially for stress analysis on components, since the gauge volume element in that caseis cubic and large vertical divergences due to focusing monochromators do not affect the spatialresolution.The instrument is now available for routine operation and here we will present details of recentexperiments and instrument performance
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 571-572 (Mar. 2008), p. 421-425 
    ISSN: 1662-9752
    Quelle: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Thema: Maschinenbau
    Notizen: Alumina-zirconia multilayered ceramics have been proposed as an alternative for thedesign of structural ceramics with improved fracture toughness and strength reliability. During theprocessing of these laminates, significant residual stresses may arise due to the thermal expansionmismatch between adjacent layers. The correct evaluation of such stress distribution in the laminatemay determine its range of application. In this work, the residual stress state in a layered materialdesigned with five thick alumina layers of approximately 650 microns alternated with four thinalumina-zirconia layers of approximately 140 microns was estimated using different methods. Afinite element analysis (FEM) was performed for stress evaluation in the bulk and an indentationmethod and X-Ray diffraction to account for stresses at the surface. Experimental findings show aconstant stress distribution within the bulk for each layer, while at the surface stress positiondependence is observed in the alumina layers, being the maximum tensile stresses near the layerinterface. The accuracy of the results provided by each technique is discussed
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Naturwissenschaften 67 (1980), S. 216-226 
    ISSN: 1432-1904
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Allgemeine Naturwissenschaft
    Notizen: Abstract Only relatively few laboratories are actively engaged in thermoluminescence-dating of rocks and artifacts. Nearly all these laboratories combine the practical application with methodical developments, because thermoluminescence-dating is too complex in order to become a routine method in the near future. This article reviews the principles and new developments and the archaeological and geological applications of thermoluminescence-dating.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    ISSN: 1573-0662
    Schlagwort(e): Biogenic sulfur ; biogenic emissions ; enclosure methods ; soils ; crops ; trees ; vegetation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Geologie und Paläontologie
    Notizen: Abstract Emission rates of reduced sulfur gases from vegetation and soils were measured in various regions of the United States during the summer of 1985. The predominant sulfur gases emitted were hydrogen sulfide, carbonyl sulfide and dimethylsulfide. Typically, vegetative (forests, crops, etc.) emission fluxes varied between approximately 10 and 60 ng S m-2 min-1. Biogenic sulfur fluxes from mollisol and histisol soils averaged 15 and 217 ng S m-2 min-1, respectively. Salt water marsh fluxes with a geometric mean of 293 ng S m-2 min-1 were the highest measured. These biogenic sulfur fluxes are somewhat lower than those measured during the SURE study at some of the same sites. The natural sulfur emission fluxes reported herein together with those data included in the two accompanying manuscripts provide the basis for developing a national inventory of reduced sulfur emissions from soils, crops and trees. When combined these data also will provide a foundation for deriving uncertainty limits associated with these flux estimates.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 7
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 16 (1982), S. 46-56 
    ISSN: 0009-2851
    Schlagwort(e): Chemistry ; Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 15 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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