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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 145 (1986), S. 46-50 
    ISSN: 1432-1076
    Keywords: Phosphoenolpyruvate carboxykinase ; Hypoglycaemia ; Giant cell hepatitis ; Fanconi syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 3-month-old girl presented with anorexia, failure to thrive and drowsiness. She was mildly icteric with hepatomegaly and peripheral oedema. Disordered liver function tests were associated with the biopsy appearances of a giant cell hepatitis and with a Fanconi syndrome. At the age of 16 weeks she collapsed with profound hypoglycaemia. Fasting also provoked hypoglycaemia with lactic acidaemia. She became increasingly irritable and hypotonic and, although initially liver and renal function improved, she deteriorated and died of hepatocellular failure and septicaemia. A post-mortem revealed massive fatty degeneration of the liver. The activity of phosphoenolpyruvate carboxykinase in her cultured skin fibroblasts was 16% of controls. Her brother died at the age of 4 weeks of sudden infant death syndrome.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    The @photogrammetric record 12 (1987), S. 0 
    ISSN: 1477-9730
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying
    Notes: Since 1960, photogrammetry has played a leading role in the acquisition of survey data within the Ordnance Survey of Northern Ireland. The decision to create a digital topographic database for Northern Ireland has changed the philosophy and practice of photogrammetry within the organisation and these changes are discussed in this paper.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    The @photogrammetric record 12 (1988), S. 0 
    ISSN: 1477-9730
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying
    Notes: The paper reviews technological developments since the Second World War and their impact as catalysts in developing the concept of digital information systems. The case for, and progress towards, the establishment of a Geographic Information System for Northern Ireland is discussed together with consideration of the possible implications elsewhere based on the experience gained in Northern Ireland.“There is a tide in the affairs of men which, taken at the flood, leads on to fortune.”Brutus in Julius Caesar, Act IV Scene iii (William Shakespeare)
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 238 (1985), S. 263-270 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Risikofaktoren für eine IVH sind: Der Transport des Frühgeborenen, schwere fetale Depressionszustände, schwere fetale Azidosen und in besonderem Maße ein mechanisch traumatisierter Geburtsmodus. Hierbei ist nicht die Traumatisierung des Kopfes, sondern die des gesamten Organismus ausschlaggebend. Es konnte nachgewiesen werden, daß sich durch Vermeiden einer traumatisierenden Entbindung die Inzidenz der IVH entscheidend senken läßt. Gleiches gilt für die Vermeidung des Transportes eines eben geborenen Frühgeborenen. Die Konsequenz aus diesen Ergebnissen muß eine möglichst lückenlose Regionalisierung aller Fälle von noch rechtzeitig erkannter drohender Frühgeburten Ze Zentren sein, in denen Geburtshilfe und neonatologische Intensivmedizin funktionell verzahnt und räumlich eng benachbart gemeinsam um das ungeschädigte Aufwachsen gefährdeter Kinder bemüht sind.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1238
    Keywords: ARDS ; Alveolar cells ; Bronchoalveolar lavage ; Lung contusion ; Polytrauma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To determine whether alveolar cells are involved in the pathogenesis of adult respiratory distress syndrome (ARDS), we assessed the distribution and function of alveolar cells from 30 polytraumatized patients with trauma-induced respiratory failure, 5 of whom also had lung contusion. Cells were obtained by bronchoalveolar lavage performed daily begining on the day of trauma and continuing for 14 days. Neutrophils constituted about 60% of lavage cells in ARDS patients with lung contusion 0–2 days after polytrauma and about 50% in ARDS patients without lung contusion. In ARDS patients with lung contusion the neutrophil fraction decreased to 52% 3–6 days after trauma and to 40% 7–14 days after trauma. In patients without lung contusion the neutrophil fraction increased to 77% and then decreased to 60% at these times. Total cell counts in ARDS patients with lung contusion were more than twice as high as in patients without lung contusion 0–2 days after trauma. The difference in total cell counts decreased during days 3–6 and disappeared by day 7. In all patients morphologically altered alveolar cells were observed 4 days and more after trauma. In non-survivors significantly more altered cells were found. The chemiluminescence-response pattern of the alveolar cells was enhanced throughout the study and correlated with the neutrophil fraction (r=0.6). The neutrophil fraction also correlated with the pulmonary vascular resistance during the first two days after trauma (r=0.53). We conclude that alveolar cells are involved in the pathogenesis of trauma-induced ARDS and that the alveolar cell distribution is different in patients with and without lung contusion during the development of posttraumatic respiratory failure.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 372 (1987), S. 833-833 
    ISSN: 1435-2451
    Keywords: Sepsis syndrome ; Immunology ; Polytrauma organ failure ; Bronchoalveolar lavage ; Polytrauma ; Immunologie ; BAL ; Organversagen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Prospektive immunologische Untersuchungen in der bronchoalveolären Lavage, im Blut und im Urin bei Polytraumatisierten sollten Marker zur Erkennung der Frühphase der Sepsis aufdecken. Die Sepsis begann bei 7 Patienten initial mit einer alveolären Zellaktivierung (Veränderung der Zellzahl und -funktion) durch Mediatorsubstanzen (Elastase, Komplementspaltprodukte, Àrachidonsäuremetabolite). Die Organschäden von Lunge, Niere, Leber und Herz-Kreislauf entwikkelten sich im Sinne von sekundären Funktionsstörungen erst 4 Tage später. Durch die Frühdiagnostik solcher Veränderungen konnten frühe therapeutische Konsequenzen eingeleitet werden.
    Notes: Summary Prospective immunological monitoring using bronchoalveolar lavage, as well as urine and blood tests in patients with multiple injuries, revealed early signs of sepsis development. Sepsis initially began in 7 patients with alveolar cell activation and capillary leakage. Lung, kidney, liver, and heart failure occurred 4 days later in the form of secondary functional disturbances. These early diagnostic signs made appropriate therapy possible.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1573-0743
    Keywords: recurrent stenosis ; quantitative coronary angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Current evidence with regard to the possible association between clinical expression of coronary disease prior to the time of angioplasty, and the subsequent risk of restenosis following successful dilatation, remains inconclusive. To prospectively compare the incidence of restenosis in stable versus unstable angina pectoris patients, follow-up angiography was performed in 85 percent of patients from a consecutive series with a successful PTCA, irrespective of presence or absence of recurrent ischemic symptoms. Furthermore, changes in lesion severity were assessed quantitatively by an automated edge-detection technique rather than visual analysis. Employing such a study design and follow-up protocol, it was found that the incidence of restenosis in patients with stable coronary artery disease was similar to that of patients with unstable rest angina, irrespective of the type of angiographic definition used.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of inherited metabolic disease 9 (1986), S. 29-30 
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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