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  • 1985-1989  (3)
  • 1
    Electronic Resource
    Electronic Resource
    AbsoluteL-subshell ionization cross-sections ofZ∼50 targets by4He ion impact (1987)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 9 (1987), S. 71-85 
    Details
    ISSN: 0392-6737
    Keywords: Atomic photon processes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si sono effettuate misure di fluorescenza X indotta da bombardamento di ioni4He di energia compresa tra 0.6 e 5.0 MeV sugli elementi Ag, Cd, In, Sn, Sb, Te e I. Utilizzando un metodo di normalizzazione interna fondato su contemporanee misure di retrodiffusione Rutherford, si sono ottenute le sezioni d’urto assolute per un certo numero di righe X. Da quelle relative alle righeL α ,L γ1,5 eL γ2,3 si sono poi ricavate le sezioni d’urto di ionizzazione per i diversi sottostratiL. Il confronto con le teorie disponibili ha evidenziato la presenza di sensibili disaccordi per tutti i bersagli al di sotto dell’energia incidente di 2.0 MeV e, per Ag, Cd ed In, anche per energie piú elevate, che sono stati attribuiti in parte ai parametri atomici disponibili per i calcoli delle sezioni d’urto ed in parte all’inadeguatezza delle teorie che descrivono il processo di ionizzazione.
    Notes: Summary The X-radiation induced by4He ion impact on Ag, Cd, In, Sn, Sb, Te and I has been investigated for incident energies ranging from 0.6 to 0.5 MeV. Production cross-sections for various X-ray lines have been obtained by an internal normalization method, by means of simultaneous backscattering measurements. From the intensities on theL α ,L γ1,5 andL γ2,3 lines theL-subshell ionization cross-sections have been extracted. Comparison with current theories shows systematic discrepancies for all the targets at incident energy below 2.0 MeV and, for Ag, Cd and In, even in the higher-energy region. These are attributed to deviations in the atomic parameters used in the data analysis as well as to a failure of the ionization theories employed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02453276
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Coronary vasomotor and clinical effects of nifedipine in effort, mixed and Prinzmetal angina (1988)
    Springer
    The international journal of cardiovascular imaging 3 (1988), S. 99-109 
    Details
    ISSN: 1573-0743
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Changes induced by nifedipine (10 mg s.l.) in the residual lumen diameter of significant (〉50%) coronary lesions were assessed angiographically in 69 patients with effort angina (Group 1), in 22 patients with mixed angina (Group 2), and in 14 patients with Prinzmetal angina (Group 3). These changes were related to the clinical response to treatment with the same drug (diary records, exercise testing, Holter monitoring). In Groups 1 and 2 segments of stenotic vessels showed either increase, decrease or no change in diameter with the calcium antagonist; in Group 3 the majority of the vessels showed compliant portions which invariably responded with dilatation. Nifedipine failed to improve cases with exertional (21% unchanged, 19% worsened) and mixed (41% exacerbated) forms; all patients with the Prinzmetal form had relief of the anginal episodes. In Group 1, the response to exercise tests were dissociated from the acute vasomotor pattern and the pressure-rate product failed to explain the clinical results. Fifty-two percent of the patients in Group 2 showed significant acute widening of critical stenoses as well as obvious improvement; patients in this group who did worse with treatment had reacted to nifedipine with narrowing of their critical stenoses. These data suggest that: the response to nifedipine of classic effort angina is probably the net result of an interaction of changes in myocardial oxygen consumption and supply; coronary vasomotion has a role in mixed angina and influences of nifedipine may be either favorable or unfavorable; stenotic lesions in the Prinzmetal form are quite sensitive to the relaxant action of calcium blockade and this probably represents a background to the highly positive clinical response to treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01814882
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Experimental allergic encephalomyelitis in guinea pig: variability of response to intradermal emulsion injection (1989)
    Springer
    Neurological sciences 10 (1989), S. 33-41 
    Details
    ISSN: 1590-3478
    Keywords: Fresh isologous spinal cord ; perivenous cuffs ; demyelination ; fibrillary gliosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Differenti forme di encefalomielite allergica sperimentale sono state realizzate in quattro gruppi di cavie con iniezione di emulsioni: il primo gruppo era di 7 cavie di tipo Hartley, il secondo era formato da 12 adulti dello stesso ceppo, il terzo da 6 soggetti di ceppo giovanile 2 e il quarto da 6 animali del ceppo giovanile 13. I gruppi 1 e 2 ricevettero emulsioni contenenti rispettivamente 250 e 500 mg. di tessuto midollare isolago fresco con composto di Freund e soluzione salina mentre i grouppi 3 e 4 ricevettero un'emulsione con 120 mg. di midollo e gli altri componenti e in più 15 mg. di mycobacterium tubercolosis. Nel gruppo 1 e 2 si sviluppò una forma morbosa con ritardato avvio e un decorso prolungato e progressivo, benché 8 animali non abbiano presentato sintomi di malattia: si riscontrava nelle cavie malate la presenza di placche vaste di demielinizzazione con fibrosi perivenosa ed area estesa di infiltrazione. In 2 animali asintomatici si è constatata un'area di demielinizzazione nella sostanza bianca del midollo. La stessa forma a lento avvio e a decorso prolungato e progressivo si è verificata in 4 animali del ceppo 2. Risultò cosi che l'aumento degli antigeni ha prodotto importanti lesioni negli animali tipo Hartley anche se non tutti gli animali presentarono sintomi di malattia e lo stesso tipo di malattia è stato indotto anche in ceppi di cavie di tipo non Hartley. Queste reattività differenziate possono essere il risultato di una parziale o completa inattivazione della risposta mediata delle cellule agli antigeni inoculati.
    Notes: Abstract Different forms of experimental allergic encephalomyelitis were obtained in 4 groups of guinea pigs: 7 adult Hartley guinea pigs (Group I), 12 adults of the same strain (Group II), 6 juvenile strain 2 guinea pigs (Group III) and 6 juvenile strain 13 animals (Group IV), by the injection of emulsions. Groups I and II received emulsions containing 250 mg and 500 mg respectively of fresh isologous spinal cord tissue, complete Freund adjuvant (CFA) and saline solution while Groups III and IV received an emulsion containing 120 mg of isologous spinal cord, CFA, saline solution and 15 mg of Mycobacterium tuberculosis. The increased antigen load induced a disease with delayed onset and prolonged progressive course (C-P-EAE) in Groups I and II, although 8 animals showed no symptoms of illness. The findings in C-P-EAE were large demyelinated plaques, perivenous fibrosis and large areas of infiltration. Demyelinated areas occurred within the spinal cord white matter only in two asymptomatic animals. C-P-EAE was obtained in 4 of the Strain 2 animals. In conclusion, the increased antigen load induced a range of lesions in Hartley guinea pigs, although not all animals were affected. C-P-EAE was induced also in strains of guinea pig other than the Heartley strain. These different reactions may have been the outcome of partial or complete inactivation of the cell-mediated response to the inoculated antigens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02333870
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    Paper (German National Licenses)
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