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  • 1
    ISSN: 1432-0533
    Keywords: Nerve growth factor receptor ; S-100β protein ; Neurofibroma ; Schwannoma ; Von Recklinghausen disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In situ expression of nerve growth factor (NGF) receptors in human dermal and plexiform neurofibroma, schwannoma and traumatic neuroma was examined by an immunohistochemical method using a monoclonal anti-human NGF receptor antibody. Immunoreactivity for the NGF receptor was observed on the principal cells of both neurofibroma and schwannoma. Immunostaining by the anti-S-100β protein antibody in adjacent sections suggested that the vast majority of NGF receptor-positive cells were also positive for S-100β protein. In traumatic neuroma, staining for the NGF receptor was more intense in the perineurium than in the endoneurial cells.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 235 (1988), S. 428-431 
    ISSN: 1432-1459
    Keywords: Anhidrosis ; Hypohidrosis ; Sweat gland ; Ventilated capsular method ; IgE
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The present study concerns a 28-year-old Japanese man with acquired generalized anhidrosis. The patient's ability to perspire was investigated in an artificial climate room maintained at 40°C and 40% humidity. Although the body temperature rose to 38°C, the patient did not sweat. Neither did sweating occur when the patient was given an intradermal injection of pilocarpine or nicotine. The serum IgE level was elevated. Atrophy and degeneration of the sweat glands, as well as infiltration by lymphocytes and mast cells around the sweat glands, were observed in skin biopsies. Anhidrosis in this patient was suggested to be the result of reduced function of the sweat glands themselves with possible underlying immunemediated basis.
    Type of Medium: Electronic Resource
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