ISSN:
1432-0533
Keywords:
Nerve growth factor receptor
;
S-100β protein
;
Neurofibroma
;
Schwannoma
;
Von Recklinghausen disease
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In situ expression of nerve growth factor (NGF) receptors in human dermal and plexiform neurofibroma, schwannoma and traumatic neuroma was examined by an immunohistochemical method using a monoclonal anti-human NGF receptor antibody. Immunoreactivity for the NGF receptor was observed on the principal cells of both neurofibroma and schwannoma. Immunostaining by the anti-S-100β protein antibody in adjacent sections suggested that the vast majority of NGF receptor-positive cells were also positive for S-100β protein. In traumatic neuroma, staining for the NGF receptor was more intense in the perineurium than in the endoneurial cells.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00687886
