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  • 2000-2004  (3)
  • 1980-1984  (3)
Materialart
Erscheinungszeitraum
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 143 (2000), S. 0 
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 150 (2004), S. 0 
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 145 (2001), S. 0 
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Background The blocking action of botulinum toxin type A (BTX-A) on cholinergically innervated sweat glands has been used successfully to treat patients with focal hyperhidrosis. Objectives To investigate the long-term efficacy and safety of intradermal injections of BTX-A. Methods We performed an open-label study in 61 patients treated over a period of 3 years for axillary or palmar hyperhidrosis. A total dose of 400 mU BTX-A (Dysport®) was injected into both axillae or 460 mU BTX-A (Dysport®) into both palms. The injections were repeated after relapse. Objective quantification of sweat production was performed using digitized ninhydrin-stained sheets. Results Four weeks after BTX-A treatment the median reduction in sweat production was 71% compared with baseline (P 〈 0·001) in the axillary group and 42% (P = 0·005) in the palmar group. Subjective assessment of sweat production by the patients using a visual analogue scale (0, no sweating; 100, the most severe sweating) showed a significant reduction in both the axillary (P 〈 0·001) and palmar groups (P 〈 0·001). Secondary disturbances due to focal hyperhidrosis interfering with daily activities were markedly improved in both groups. The median time interval between the sets of injections was 34 weeks for axillary hyperhidrosis and 25 weeks for palmar hyperhidrosis. The treatment of palmar hyperhidrosis was complicated by transient but not disabling weakness of the small hand muscles in nine of 21 patients. Conclusions Repeated intradermal injections of BTX-A in patients with axillary and palmar hyperhidrosis are as effective as first treatments.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Cellular and molecular life sciences 38 (1982), S. 898-899 
    ISSN: 1420-9071
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary For the first time we have isolated a major psychoactive cannabinoid, (3R, 4R)-Δ 1(6)-tetrahydrocannabinol3 from callus cultures ofCannabis sativa L.3 was obtained as an artefact of the actually formed (3R, 4R)-Δ 1-tetrahydrocannabinol-3′- and/or 5′-carboxylic acids1 and2 by subjecting the culture material to a decarboxylation step prior to extraction. No attempt was made to isolated acids1 and2. The identity of3 was confirmed by comparison with an authentic sample of (3R, 4R)-Δ 1-tetrahydrocannabinol. Culture conditions, isolation procedure and identification of the cannabinoid are described.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 5
    ISSN: 1432-1076
    Schlagwort(e): Pesticides ; Fat tissue ; Children ; Mothers' milk intake
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Chlorinated hydrocarbon and polychlorinated biphenyl (PCB) concentrations were determined in adipose tissue from 34 infants, 14 children in the 2nd year of life, and 2 older children. The highest mean concentration detected during the first 2 years of life was for PCBs (0.67 ppm), followed by DDT (0.57 ppm), HCB (0.23 ppm), and HCH (0.15 ppm). Concentrations of HCB and PCB, which are especially characteristic of highly industrialised countries, were considerably higher in children of German mothers than in those of Turkish mothers. All single investigated values were lower than the mean values for adults in the Federal Republic of Germany, but many were still higher than mean concentrations for adults in other parts of the world. A breakdown into children with high mothers' milk intake and those with low intake showed a highly significant association with the quantity of mothers' milk consumed: the concentration of organohalogens in adipose tissue of children with high intake was significantly higher than in those with low intake. Two tasks urgently demand our attention: the development of further ways to reduce environmental sources of organohalogen contamination and the study of the possible pathogenetic effect of these organohalogens on the health of our children.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 43 (1981), S. 186-192 
    ISSN: 1432-1106
    Schlagwort(e): Tendon organ ; Muscle receptor
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The model of tendon organ activation proposed by Houk and Henneman (1967) has been tested by considering two of its implicit predictions: (1) that only a select group of motor units within a muscle can provide an adequate stimulus to a given tendon organ; and (2) that due to the presence of motor units that can “unload” a given tendon organ, its response to whole muscle contraction can be less vigorous than that to contraction of just the excitatory motor units alone. Tendon organ afferents from the soleus muscle of the cat were functionally isolated from dorsal root filaments. The L7 and S1 ventral roots were split into 25 to 50 “natural” subdivisions, each of which was stimulated at 50 to 100 Hz for 1.5 s. The subdivided filaments were segregated into two groups; those which when stimulated elicited discharge from the Ib afferent (“excitatory” filaments) and those which did not (“non-excitatory” filaments). In ten of eleven experiments, it was found that when all the excitatory filaments were separated out, concurrent stimulation of all the non-excitatory filaments failed to excite the tendon organ, even when these filaments generated over 90% of the muscle's peak tetanic tension. The response of a tendon organ to stimulation of just its excitatory filaments often exceeded its response to whole muscle stimulation. However, several exceptions to this finding were observed, indicating that some tendon organs are affected by “off-line” forces. In general, the present results lend strong support to the Houk and Henneman model.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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