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  • Artikel: DFG Deutsche Nationallizenzen  (17)
  • 1985-1989  (11)
  • 1980-1984  (6)
Datenquelle
  • Artikel: DFG Deutsche Nationallizenzen  (17)
Materialart
Erscheinungszeitraum
Jahr
Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    The effects of forsterite film on total loss of grain-oriented 3% silicon iron (1985)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 57 (1985), S. 4214-4216 
    Details
    ISSN: 1089-7550
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Two types of mill glass, one of which is conventional and the other is characterized by its irregular surface morphology and stronger tension, were prepared on the surface of high permeability 3%Si-Fe sheets in order to clarify the effects of the mill glass on core loss and domain structure. The results are twofold. Firstly, the mill glass of the latter type was, by itself, found to reduce the total loss in the induction range of 1.7 T. Secondly, considerable change in magnetization, characterized by its heavily constricted curve occurred, and corresponding change in the domain structure was observed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1063/1.334617
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  • 2
    Digitale Medien
    Digitale Medien
    Epstein-Barr Virus-induced Lymphoblastoid Cell Lines from Patients with Primary Immunodeficiency Diseases (1980)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 11 (1980), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Peripheral lymphocytes from eight patients with congenital immunodeficiency diseases were infected with Epstein-Barr virus (EBV) in an attempt to establish B lymphoblastoid cell lines (LCL). These patients included three boys with congenital agammaglobulinaemia, two girls with hypogammaglobulinaemia, one boy with common variable immunodeficiency, one boy with severe combined immunodeficiency with adenosine deaminase deficiency, and one boy with DiGeorge syndrome. Five of the patients bore no surface immunoglobulins (slg) on their peripheral lymphocytes. LCL were established from seven of the eight patients. All the LCL established formed rosettes with EAC3 and had the ability to produce cytoplasmic immunoglobulins (clg) of various classes. Culture supernatants concentrated up to 100-fold developed precipitin bands by Ouchterlony's method with antisera to human Ig in all the established LCL. These results suggested that both slg-, clg- and C3+ cells and slg+, clg- and C3+ cells might be the target cells for EBV and that slg-, clg- and C3+ cells might be the precursor cells of B lymphocytes.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3083.1980.tb00221.x
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  • 3
    Digitale Medien
    Digitale Medien
    Effect of trypsin and chymotrypsin on polypeptides of human rotavirus KUN strain (1987)
    Springer
    Medical microbiology and immunology 176 (1987), S. 65-73 
    Details
    ISSN: 1432-1831
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract In view of the fact that trypsin enhances the infectivity of human rotavirus and decreases its hemagglutination, the trypsin-mediated structural modification of the viral polypeptides was analysed, using the KUN strain, a cultivable human rotavirus isolate, grown in the absence of trypsin. A major polypeptide sensitive to trypsin treatment was Vp4 with a molecular weight of 80,000, being cleaved into three polypeptides with molecular weights of 54,000 (P54), 30,000 (P30), and 24, 000 (P24). Vp4 was also sensitive to chymotrypsin treatment, generating cleavage products different from those obtained with trypsin.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00200676
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  • 4
    Digitale Medien
    Digitale Medien
    Further observations on the morphogenesis of human rotavirus in MA 104 cells (1984)
    Springer
    Archives of virology 79 (1984), S. 147-159 
    Details
    ISSN: 1432-8798
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Human rotavirus “KUN” strain was cultivated in a fetal rhesus monkey kidney cell line, MA 104 cells. Four types of virus particles in cells infected with KUN strain were clearly identified: nucleoid cores, single-shelled particles, double-shelled particles, and membrane band, “enveloped” particles. “Enveloped” particles were found only in the thin sections of infected cells. When first visible, the virus precursors appeared at the ribosome free membrane of rough endoplasmic reticulum (RER), increasing in size while simultaneously being coated with nucleocapsid, inner shell. Single-shelled particles were also synthesized within bundles of filaments of viroplasm in the cytoplasma. During subsequent virus maturation two types of “budding” processes were observed. Double-shelled particles arising at the RER membrane entered the cisternae of the RER through an exocytosis-like process. In contrast, the “enveloped” particles developed in the cisternae by being completely enclosed with RER membrane, and later during cytolysis released the single-shelled particles. These “enveloped” virus particles appeared to be the result of inefficient virus maturation at the last stage of outer capsid formation.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01310808
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  • 5
    Digitale Medien
    Digitale Medien
    Serum bile acids and their conjugates in breast-fed infants with prolonged jaundice (1985)
    Springer
    European journal of pediatrics 144 (1985), S. 37-40 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Serum bile acid ; Breast milk jaundice
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Serum bile acids and their conjugates were analysed in 20 breast-fed infants with prolonged jaundice. The mean total bile acid levels in serum were increased in the breast-fed infants with jaundice, as compared with those in either breastor bottle-fed infants without jaundice. However, there were no significant differences between the groups. All the breast-fed infants examined, regardless of association with jaundice, had a bile acid pattern dominated by taurine conjugates (the ratio of glycine- to taurine-conjugated bile acid, G/T ratio, less than 1.00). In contrast, the bottle-fed infants without jaundice had a pattern dominated by glycine conjugates (G/T ratio, more than 1.00). Among the breast-fed infants with jaundice, the mean G/T ratio in those who had serum bilirubin levels over 10 mg/100 ml was significantly lower than that in those who had serum bilirubin levels of less than 10 mg/100 ml. The altered bile acid metabolism might be associated with the pathology of breast milk jaundice.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00491922
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  • 6
    Digitale Medien
    Digitale Medien
    Successful transplantation of soy bean agglutinin-fractionated, histoincompatible, maternal marrow in a patient with severe combined immunodeficiency and BCG infection (1985)
    Springer
    European journal of pediatrics 143 (1985), S. 291-294 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Severe combined immunodeficiency ; HLA-haplotype mismatched bone marrow transplantation ; Soy bean agglutinin ; BCG infection
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract A successful transplantation of soybean agglutinin (SBA) and sheep red blood cell (SRBC)-fractionated, maternal marrow in a patient with severe combined immunodeficiency (SCID) is reported. The engraftment of HLA-haplotype mismatched marrow cells was obtained without apparent graft versus host disease (GVHD). With immunological reconstituion the patient recovered from a BCG infection, which might have been caused by a BCG inoculation before his bone marrow transplantation.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00442303
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  • 7
    Digitale Medien
    Digitale Medien
    Significance of serum lipoprotein-X and gammaglutamyltranspeptidase in the diagnosis of biliary atresia. A preliminary study in 27 cholestatic young infants (1986)
    Springer
    European journal of pediatrics 145 (1986), S. 54-57 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Lipoprotein-X ; γ-Glutamyltranspeptidase ; Biliary atresia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract As simple and nonsurgical means of differentiating biliary atresia (BA) from intrahepatic cholestasis of unknown origin (IC), liver function tests including serum lipoprotein-X (LP-X) and γ-glutamyltranspeptidase (GGTP) were done and evaluated for their usefulness in the diagnosis of 27 cholestatic Japanese young infants. Except for LP-X and GGTP levels (P〈0.01, P〈0.001), there were no significant differences between the BA (n=11) and IC (n=13) groups. When values of mean plus 4 standard deviations were used to differentiate BA from IC (89 mg/100 ml for LP-X and 194 IU/l for GGTP), all BA patients gave positive results for either the crtical LP-X of GGTP values. On the other hand, all IC patients gave negative results for both levels, although patients with a paucity of intrahepatic biliary ducts (n=3) were also positive for either the critical LP-X or GGTP values. The combination test with serum LP-X and GGTP is recommended for helping to differntiate BA from IC in cholestatic young infants.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00441853
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  • 8
    Digitale Medien
    Digitale Medien
    d-lactic acidosis in two patients with short bowel syndrome: Bacteriological analyses of the fecal flora (1982)
    Springer
    European journal of pediatrics 138 (1982), S. 324-326 
    Details
    ISSN: 1432-1076
    Schlagwort(e): d-lactic acidosis ; Short bowel syndrome ; Lactobacillus ; Kanamycin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Two cases of d-lactic acidosis associated with short bowel syndrome are described. The administration of kanamycin to the patients showed a decrease in d-lactate in blood and urine in parallel with disappearance of metabolic acidosis. Bacteriological analyses of the fecal flora showed an increase in Lactobacillus buchneri in the first patient and Lactobacillus fermenti IVa in the second; both bacteria were sensitive to kanamycin. Quantification of in vitro production of d-lactate by each species of bacteria isolated from the feces revealed that Lactobacillus produced more d-lactate than other species of bacteria. These observations indicate that Lactobacillus may play an important role in the induction of d-lactic acidosis in patients with short bowel syndrome.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00442509
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  • 9
    Digitale Medien
    Digitale Medien
    Prevention of rotavirus infection by oral administration of cow colostrum containing antihumanrotavirus antibody (1985)
    Springer
    Medical microbiology and immunology 174 (1985), S. 177-185 
    Details
    ISSN: 1432-1831
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract After immunizing 8-month pregnant Holstein cows with human rotavirus, Wa strain, cow colostrum containing neutralizing antibody to human rotavirus, designated as Rota colostrum, was obtained. After randomly grouping 13 infants from a single orphanage, 6 infants received 20 ml of Rota colostrum every morning and 7 control infants received 20 ml of market milk. One month later, rotavirus associated diarrhea was observed in 6 of the 7 infants given milk and 1 out of the 6 infants given Rota colostrum. Orally administered Rota colostrum significantly protected infants from diarrhea caused by rotavirus (P 〈 0.05). Two out of 5 Rota colostrum recipients who were free from diarrhea showed rises in complement fixation (CF) antibody titer after the rotavirus infection epidemic. Thus, Rota colostrum prevented the outbreak of diarrhea but did not prevent immunological responses to natural rotavirus infection. In the therapeutic trial Rota colostrum had no effect on duration of diarrhea, bowel movements or virus shedding in stool. However, there were no side-effects of Rota colostrum.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02123694
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  • 10
    Digitale Medien
    Digitale Medien
    Effect of hypertonic conditions on protein synthesis in MA104 cells infected with human rotavirus (1985)
    Springer
    Medical microbiology and immunology 174 (1985), S. 211-220 
    Details
    ISSN: 1432-1831
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract When a high NaCl concentration was used to decrease selectively the synthesis of cell proteins, the synthesis of most cellular polypeptides was greatly diminished relative to human rotavirus proteins. Thus, in the presence of 150 mM excess NaCl, 11 viral polypeptides were clearly identified. However, hypertonic conditions also reduced viral protein synthesis to a different extent with individual proteins. No significant changes in viral protein synthesis occurred during incubation under the hypertonic condition for up to 6 h, and infectious virus yields of MA104 cells incubated in the hypertonic medium did not differ from the yields of untreated MA 104 cells. These results indicate that hypertonic conditions provide a useful tool for qualitative studies of viral protein synthesis in human rotavirus infected cells.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02123698
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